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Aaron Wood
Partagé en mode public -A single-application bioengineered gel, squirted in the ear canal, could deliver a full course of antibiotic therapy for middle ear infections, making treatment of this common childhood illness much easier and potentially safer, finds a preclinical study led by Boston Children’s Hospital in collaboration with investigators at Boston Medical Center and Massachusetts Eye and Ear. The findings were published September 14 by the journal Science Translational Medicine.
Squirted into the ear canal, the gel quickly hardens and stays in place, gradually dispensing antibiotics across the eardrum into the middle ear. Previously, the eardrum (also called the tympanic membrane) was an impenetrable barrier. The bioengineered gel gets drugs past it with the help of chemical permeation enhancers (CPEs), compounds FDA-approved for other uses that are structurally similar to the lipids in the stratum corneum, the eardrum’s outermost layer. The CPEs insert themselves into the membrane, opening up molecular pores that allow the antibiotics to seep through.
Paper:
http://stm.sciencemag.org/content/8/356/356ra120
PR:
http://www.childrenshospital.org/news-and-events/2016/september-2016/antibiotic-gel-squirted-into-the-ear-could-provide-a-one-dose-cure-for-ear-infections
#research #tympanicmembrane #earinfection #science
Aaron Wood
Partagé en mode public -I think that for me, the show manages to distill so many movies all at once, without ever becoming a cliche or copy of any other them. At one point I expected to an E.T. bicycle moment, and instead got treated to some much more modern-inflected (and cool) effects instead.
The movie just nails my childhood. I keep coming back to the Trapper Keepers and other details of day-to-day life, the interior decoration, and the vehicles. It's just uncannily spot-on. They did incredible amounts of research and effort into the reconstruction of my youth.
And then the setting. Late fall in the Midwest is bleak and barren, and is exactly the right time of year for this sort of story. Walking in the woods leaves nearly no trace when the wind is blowing the leaves around. It's easy to vanish. I don't think any other season would have worked nearly so well.
Aaron Wood
Partagé en mode public -Gibbon Falls
Yellowstone National Park
Aaron Wood
Partagé en mode public -"I'm a guy who loves photography and adventure! In fact I've been taking and developing my photos for over 25 years! Recently I've decided to travel around America in my truck and capture its beauty with my camera. I'd love it if you would follow along on my journey! Even better would be to meet you along the way and go shooting together!"
Check out our favorite Collections by John: Photoshop fun (https://plus.google.com/collection/4-nyPB) and Portraits (https://plus.google.com/collection/s7yxPB).
Aaron Wood
Partagé en mode public -#craftbeer #monkeypaw
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Aaron Wood
Partagé en mode public -
Aaron Wood
Partagé en mode public -/pulls hair out
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Texas Truck of Terror reason.com How an American plumber's truck wound up in the hands of Syrian rebels. |
2015 Tesla Model S P85D First Test - Motor Trend www.motortrend.com An exclusive from Motor Trend: We track-test the incredible new 2015 Tesla Model S P85D. Get the full story, with plenty of unique Model S P |
The never-advertised, always coveted headphones built and sold in Brooklyn arstechnica.com Ars presents a mini-documentary on the low-profile, highly regarded Grado Labs. |
Biggest “patent troll” slapped down hard by appeals court arstechnica.com Dozens of companies were sued over an old Polaroid digital imaging patent. |
California police use of body cameras cuts violence and complaints www.theguardian.com Body cameras worn by police in Rialto, California have resulted in better policing – and now other forces may follow suit |
At Le Mans, the Michelin tent is more interesting than you'd think www.roadandtrack.com At the most famous endurance race in the world, it's easy to focus on the drivers and team strategies, but what's happening where the car me |
Good Badlands: Dry Terrain of the American West Captured in a Brief Mome... www.thisiscolossal.com The Badlands are a type of parched, sunbaked terrain characterized by jagged rock, cracked earth and, of course, minimal vegetation. It’s a |
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lines and colors :: a blog about drawing, painting, illustration, comics... linesandcolors.com A blog about drawing, painting, illustration, comics, webcomics, cartoons, concept art and other visual arts. |
Netflix et Comcast ont-ils cassé l'Internet? www.zdnet.fr L'annonce la semaine dernière du deal entre Netflix et Comcast concernant les flux du premier sur le réseau du dernier a fait beaucoup de br |
Very early warning of next El Niño www.pnas.org Abstract The most important driver of climate variability is the El Niño Southern Oscillation, which can trigger disasters in various parts |
Schneier on Security: Breaking Up the NSA www.schneier.com Jon • February 25, 2014 6:55 AM. There were some comments on Slashdot stating that the FBI is not meant to intelligence but more for investi |
'Eye of the Tiger' Played on a Dot Matrix Printer laughingsquid.com "Eye of the Tiger" by Survivor is recreated with surprising accuracy by a dot matrix printer in this 2013 video by MIDIDesaster. To create t |
Inflation-Adjusted S&P500 Chart - All Star Charts with JC Parets allstarcharts.com As market participants we look at charts every day for a variety of reasons. But whether we’re doing so for idea generation, risk management |
15 Rare Photos of New York’s Graffiti-Covered Subway in the 1980s | Ligh... lightbox.time.com TIME contract photographer Christopher Morris' previously unpublished images of New York's subway in the 1980s show us a world long gone. |
Should You Remove the Green Germ from Garlic? | David Lebovitz www.davidlebovitz.com Should you or shouldn't you remove the green germ from garlic? |
