5 Photos - Feb 19, 2015
Photo: PDB: 1w1c CYTOPLASMICPhoto: PDB: 1w1e MITOCHONDRIALPhoto: PDB: 3QFB the TR1 structure PDB: 3QFB) are the mechanism(s) for the incorporation of Se into TrxRs as the amino acid selenocysteine (Sec) as well as for delivery to a variety of secondary substrates or TRX PDB: 1TRS (Lower Right) PMID:20536427, GLUTAREDOXIN PDB: 1JHB (lower Left) PMID:11259642.Photo: the enzyme Gly-499 of the subunits active Cys-497-498-TRXR1 (PDB: 3QFB) in nuclei provide means to quantify glutathione (GSH) (PDB: 3H8Q) conditions of the active GRX functonally and structurally analogus to TGR (selenodiglutathione) reductase.Photo: Reactome
Event Hierarchy:   
Cellular responses to stress
 
Detoxification of Reactive Oxygen Species

TXNRD2 catalyzes the reduction of TXN2 by NADPH
       [Mitochondrial Matrix]
Taken from: The download options for the selected pathway [PDF]
http://www.reactome.org/PathwayBrowser/#DIAGRAM=3299685&ID=3323050&PATH=2262752&DTAB=DT