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Neurons involved in learning, memory preservation less stable, more flexible than once thought
The human brain has a region of cells responsible for linking sensory cues to actions and behaviors and cataloging the link as a memory. Cells that form these links have been deemed highly stable and fixed. Now, the findings of a Harvard Medical School study conducted in mice challenge that model, revealing that the neurons responsible for such tasks may be less stable, yet more flexible than previously believed. The results, published Aug. 17 in the journal Cell, cast doubt on the traditional notion that memory formation involves hardwiring information into the brain in a fixed and highly stable pattern. The researchers say their results point to a critical plasticity in neuronal networks that ensures easier integration of new information. Such plasticity, the researchers said, allows neuronal networks to more easily incorporate new learning, eliminating the need to form new links to separate neurons every time. Furthermore, they said, once a memory is no longer needed, neurons can be more easily reassigned to other important tasks. "Our experiments point to far less stability in neurons that link sensory cues to action than we would have expected and suggest the presence of much more flexibility, and indeed a sort of neuronal efficiency," said study senior author Chris Harvey, an assistant professor of neurobiology at Harvard Medical School. "We believe this trade-off ensures the delicate balance between the ability to incorporate new information while preserving old memories."
The human brain has a region of cells responsible for linking sensory cues to actions and behaviors and cataloging the link as a memory. Cells that form these links have been deemed highly stable and fixed. Now, the findings of a Harvard Medical School study conducted in mice challenge that model, revealing that the neurons responsible for such tasks may be less stable, yet more flexible than previously believed. The results, published Aug. 17 in the journal Cell, cast doubt on the traditional notion that memory formation involves hardwiring information into the brain in a fixed and highly stable pattern. The researchers say their results point to a critical plasticity in neuronal networks that ensures easier integration of new information. Such plasticity, the researchers said, allows neuronal networks to more easily incorporate new learning, eliminating the need to form new links to separate neurons every time. Furthermore, they said, once a memory is no longer needed, neurons can be more easily reassigned to other important tasks. "Our experiments point to far less stability in neurons that link sensory cues to action than we would have expected and suggest the presence of much more flexibility, and indeed a sort of neuronal efficiency," said study senior author Chris Harvey, an assistant professor of neurobiology at Harvard Medical School. "We believe this trade-off ensures the delicate balance between the ability to incorporate new information while preserving old memories."
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![[Update: Name likely Oreo] Google has an Android O event on August 21st to coincide with the eclipse](http://lh3.googleusercontent.com/proxy/Vs7VdrgOPgP4oIgoMcGULv8SkdCM0BHMAEP_mC_V2wCFvvhiDcPIJK6aBaOyBSDVW6qkpkHsm-E8Xv3IjRDRd7h3Mpc922oDsyJwpoeI_xtzUt7EiQcCpLD24PifYit875WU7tZTI3PZXMQyGQm2mDuinqU=w265-h120-p)
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#NASCAR Dale Earnhardt Jr. - "What in the hell is going on in this world?" https://www.motorsport.com/nascar-cup/news/nascar-dale-earnhardt-jr-charlottesville-942364/ via @Motorsport_Oz
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Advocacy groups push Portugal to use open source to stop losing control over its digital assets
To stop losing control over its digital assets, the Portuguese government should make a sincere move to free and open source software, the country’s open source trade group ESOP says. The business association is not convinced that Portugal’s new ICT strategy, published in July, will help.
Increasing the use of open source software solutions in public administration is one of the many measures set out in Portugal’s new ICT strategy. The aim is similar to those of other EU Member States, ESOP told Open Source Observatory (OSOR) by email: “Portugal is aligned with the majority of the EU by stating that it needs to expand its use of open source.”
However, public administrations in Portugal and elsewhere are doing the opposite, ESOP told OSOR: “European governments are less and less in control of their digital assets, as they continue to use proprietary ICT, including cloud solutions.” The lack of commitment to open source is hampering the growth of an independent European software industry, the trade group says.
See https://joinup.ec.europa.eu/community/osor/news/advocacy-groups-push-portugal-use-open-source
To stop losing control over its digital assets, the Portuguese government should make a sincere move to free and open source software, the country’s open source trade group ESOP says. The business association is not convinced that Portugal’s new ICT strategy, published in July, will help.
Increasing the use of open source software solutions in public administration is one of the many measures set out in Portugal’s new ICT strategy. The aim is similar to those of other EU Member States, ESOP told Open Source Observatory (OSOR) by email: “Portugal is aligned with the majority of the EU by stating that it needs to expand its use of open source.”
However, public administrations in Portugal and elsewhere are doing the opposite, ESOP told OSOR: “European governments are less and less in control of their digital assets, as they continue to use proprietary ICT, including cloud solutions.” The lack of commitment to open source is hampering the growth of an independent European software industry, the trade group says.
See https://joinup.ec.europa.eu/community/osor/news/advocacy-groups-push-portugal-use-open-source
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NBA Draft Prospects - Michael Porter Jr.
Preseason Breakdown
NBA Comparison: Kevin Durant
With Brandon Ingram, Johnathan Isaac, Kevin Knox coming along in very recent draft classes, I personally stayed away from the Kevin Durant comparisons as they were either not at that level or missing a significant skill/ability that makes Kevin Durant the player he is. However, watching Michael Porter, this all changes. Porter is the definition of a transcendent, generational talent. He is the best scorer to come out of high school since Durant, and has the potential to become just as versatile in that aspect. One of Porter's strongest assets in his game is his pull-up jumper, which he uses very similarly to how Durant utilizes it. He looks to come into the league and immediately become an impactful scorer with the potential to become a solid defender due to his length. The taller ball handling wings are almost always compared to Durant eventually, but Porter is the one truly deserving of the comparison.
Strengths:
Averaging 37 PPG on 50% in high school, Porter Jr. is one of the best scoring prospects of the decade. His 6'10" frame and 7' wingspan allow him to finish easily at the rim, and his evasive/acrobatic finishes allow him to be highly efficient at the rim. The same size advantage allows Porter's jumpshot to prosper, as he can simply shoot over the majority of his defenders, a skill he has seemingly mastered at the high school level. The jumpshot itself is elite, with a lethal pull up game that will translate to all levels. Porter shot 69.7% from the 3PT line during his senior season at Nathan Hale, which is absolutely insane efficiency. His ball handling is also improving, as Porter has gone through more point guard-style training recently. This has allowed him to have a low amount of turnovers, averaging only 0.7 turnovers per game on a relatively high usage during his high school season. Defensively, Porter projects to be a very great help defender, with potential to be a decent rim protector. This, along with his dominant rebounding will give Porter the ability to consistently play the Power Forward. This rebounding wasn't only great at the high school level, (14.3 RPG in HS) but also against national competition, (14.0 RPG per 40 minutes at Nike EYBL), and internationally (10.6 RPG per 40 minutes at 2016 FIBA Chile Tournament).
Weaknesses:
Porter's ability as a complete player limits his weaknesses, as he has nothing that truly stands out as problematic, but there a only a few low points in his game. Porter's off ball play on the perimeter and as a cutter could improve due to how good he is as a lob target. Porter's handles are improving as already stated, but they still could be worked on if he wants to become the dominant scoring wing he is projected to be. And lastly, Porter looks to be a fairly mediocre on-ball defender, which is still something that he could improve over time.
Preseason Breakdown
NBA Comparison: Kevin Durant
With Brandon Ingram, Johnathan Isaac, Kevin Knox coming along in very recent draft classes, I personally stayed away from the Kevin Durant comparisons as they were either not at that level or missing a significant skill/ability that makes Kevin Durant the player he is. However, watching Michael Porter, this all changes. Porter is the definition of a transcendent, generational talent. He is the best scorer to come out of high school since Durant, and has the potential to become just as versatile in that aspect. One of Porter's strongest assets in his game is his pull-up jumper, which he uses very similarly to how Durant utilizes it. He looks to come into the league and immediately become an impactful scorer with the potential to become a solid defender due to his length. The taller ball handling wings are almost always compared to Durant eventually, but Porter is the one truly deserving of the comparison.
Strengths:
Averaging 37 PPG on 50% in high school, Porter Jr. is one of the best scoring prospects of the decade. His 6'10" frame and 7' wingspan allow him to finish easily at the rim, and his evasive/acrobatic finishes allow him to be highly efficient at the rim. The same size advantage allows Porter's jumpshot to prosper, as he can simply shoot over the majority of his defenders, a skill he has seemingly mastered at the high school level. The jumpshot itself is elite, with a lethal pull up game that will translate to all levels. Porter shot 69.7% from the 3PT line during his senior season at Nathan Hale, which is absolutely insane efficiency. His ball handling is also improving, as Porter has gone through more point guard-style training recently. This has allowed him to have a low amount of turnovers, averaging only 0.7 turnovers per game on a relatively high usage during his high school season. Defensively, Porter projects to be a very great help defender, with potential to be a decent rim protector. This, along with his dominant rebounding will give Porter the ability to consistently play the Power Forward. This rebounding wasn't only great at the high school level, (14.3 RPG in HS) but also against national competition, (14.0 RPG per 40 minutes at Nike EYBL), and internationally (10.6 RPG per 40 minutes at 2016 FIBA Chile Tournament).
Weaknesses:
Porter's ability as a complete player limits his weaknesses, as he has nothing that truly stands out as problematic, but there a only a few low points in his game. Porter's off ball play on the perimeter and as a cutter could improve due to how good he is as a lob target. Porter's handles are improving as already stated, but they still could be worked on if he wants to become the dominant scoring wing he is projected to be. And lastly, Porter looks to be a fairly mediocre on-ball defender, which is still something that he could improve over time.
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Steve Bannon Takes His Street Fight Outside - Steve Bannon told allies he didn’t expect to remain in the Trump White House longer than eight to 12 months – and he was right. The president’s most controversial aide, who was dismissed by White House chief of staff John Kelly, was brought down by the same qualities that endeared him to Trump and made him a valued confidant on the campaign trail: his sharp elbows and his intuitive understanding of the populist voters that helped boost Trump to ...
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Eye Test Could Predict Alzheimer's Years Before Symptoms Appear
Cedars-Sinai neuroscience investigators have found that Alzheimer's disease affects the retina -- the back of the eye -- similarly to the way it affects the brain. The study also revealed that an investigational, noninvasive eye scan could detect the key signs of Alzheimer's disease years before patients experience symptoms.
The research is in JCI Insight. (full open access)
Cedars-Sinai neuroscience investigators have found that Alzheimer's disease affects the retina -- the back of the eye -- similarly to the way it affects the brain. The study also revealed that an investigational, noninvasive eye scan could detect the key signs of Alzheimer's disease years before patients experience symptoms.
The research is in JCI Insight. (full open access)
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Seattle 2017
© Karolina Trapp
#BreakfastArtClub #HQSPUrbanStreetPhotos +HQSP Street & Documentary
#BTPStreetPro – +BTP Street PRO . founded by +Rinus Bakker , owned by +Nancy Dempsey ,curated by +Hans-Juergen Werner
© Karolina Trapp
#BreakfastArtClub #HQSPUrbanStreetPhotos +HQSP Street & Documentary
#BTPStreetPro – +BTP Street PRO . founded by +Rinus Bakker , owned by +Nancy Dempsey ,curated by +Hans-Juergen Werner
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"Another night in BC"
By Vince Constantine www.vinceconstantine.com Tucked away in a mossy forest for the night. Fell asleep to the smell of camp fire and the soft white noise of rain. - Vince Constantine
#photography #landscape #britishcolumbia #forest
By Vince Constantine www.vinceconstantine.com Tucked away in a mossy forest for the night. Fell asleep to the smell of camp fire and the soft white noise of rain. - Vince Constantine
#photography #landscape #britishcolumbia #forest
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Rattle And Hum -- Fort Collins, Colorado
This is the rattle of a two-foot-long Prairie Rattlesnake ( Crotalus viridis ) that showed up next to the sidewalk of my office building yesterday. He had gotten caught in some plastic landscape netting (dastardly stuff that should be completely banned, BTW) and couldn't escape. With the help of another guy holding the snake's head with a pair of snake tongs, I was able to cut away the netting with a pair of scissors. The snake was understandably agitated, but all things considered was remarkably calm. The liberated rattler was then relocated further into the Rocky Mountain foothills nearby. :)
If you're a landscaper or similar, please do not use plastic (or any other) landscape netting, ever - it's a death trap for small creatures of all kinds, especially snakes, lizards, and birds.
For #hqspanimals for +HQSP Animals, and #hqspmacro for +HQSP Macro, and #macromaniacs for +MacroManiacs and +Sandra Deichmann, and #Macro4All by +Bill Urwin, +Thomas Kirchen, +Walter Soestbergen (+Macro4All ), and #ReptileMonday +Reptile Monday curated by +Nicole Best...
This is the rattle of a two-foot-long Prairie Rattlesnake ( Crotalus viridis ) that showed up next to the sidewalk of my office building yesterday. He had gotten caught in some plastic landscape netting (dastardly stuff that should be completely banned, BTW) and couldn't escape. With the help of another guy holding the snake's head with a pair of snake tongs, I was able to cut away the netting with a pair of scissors. The snake was understandably agitated, but all things considered was remarkably calm. The liberated rattler was then relocated further into the Rocky Mountain foothills nearby. :)
If you're a landscaper or similar, please do not use plastic (or any other) landscape netting, ever - it's a death trap for small creatures of all kinds, especially snakes, lizards, and birds.
For #hqspanimals for +HQSP Animals, and #hqspmacro for +HQSP Macro, and #macromaniacs for +MacroManiacs and +Sandra Deichmann, and #Macro4All by +Bill Urwin, +Thomas Kirchen, +Walter Soestbergen (+Macro4All ), and #ReptileMonday +Reptile Monday curated by +Nicole Best...
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Raspberry Pi Radio @Raspberry_Pi #PiDay #RaspberryPi
https://blog.adafruit.com/2017/08/18/raspberry-pi-radio-raspberry_pi-piday-raspberrypi/
Beautiful build and tutorial from instructables user Marcel.
This retro looking radio was made from an old radio. Inside a Raspberry Pi and some other components were placed to make it work via the internet. It uses radio streams from the internet.
Read more
https://blog.adafruit.com/2017/08/18/raspberry-pi-radio-raspberry_pi-piday-raspberrypi/
https://blog.adafruit.com/2017/08/18/raspberry-pi-radio-raspberry_pi-piday-raspberrypi/
Beautiful build and tutorial from instructables user Marcel.
This retro looking radio was made from an old radio. Inside a Raspberry Pi and some other components were placed to make it work via the internet. It uses radio streams from the internet.
Read more
https://blog.adafruit.com/2017/08/18/raspberry-pi-radio-raspberry_pi-piday-raspberrypi/
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The 2017 Houston Texans Cheerleaders - NFL a mi modo. - bit.ly/2fRYtOi
Take a look at who made this year's Houston Texans Cheerleaders team!
Registration is Now Open for Houston Texans Jr. Cheerleaders!Has your little cheerleader always wanted to perform in front of thousands?Now's their chance! Houston Texans Jr. Cheerleaders presented by Texas Children's Hospital Performance:Texans vs New England PatriotsDuring pregame ceremoniesSaturday, August 19, 20177:00 PM Kickoff Mandatory Rehearsal:Sunday, August 13, 20171:00 PM -...
#Sports #NFL #Cheerleaders
(Credit: NFL a mi modo.)
Take a look at who made this year's Houston Texans Cheerleaders team!
Registration is Now Open for Houston Texans Jr. Cheerleaders!Has your little cheerleader always wanted to perform in front of thousands?Now's their chance! Houston Texans Jr. Cheerleaders presented by Texas Children's Hospital Performance:Texans vs New England PatriotsDuring pregame ceremoniesSaturday, August 19, 20177:00 PM Kickoff Mandatory Rehearsal:Sunday, August 13, 20171:00 PM -...
#Sports #NFL #Cheerleaders
(Credit: NFL a mi modo.)
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August 19/2017 will have the waning Moon and Venus in close proximity (2Dimension), and on 21st there will be our Moon, Sun and Venus close to conjunction- so that risk of a Killer > 6.4M will be Large! Further- the path of the Eclipse will pass over junction of Mississippi and Ohio Rivers- incr. Chance of a smaller New Madrid IL 1811-12 quake via microcracks at the Conjunction! Watch at 12:30 pm sky and earthquake-report.com
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Prem Watsa's Fairfax Financial Holdings is in advance negotiations with Infibeam Incorporation Limited, India's only listed and profitable ecommerce company, to pick up a minority 10-12 per cent stake for around Rs 1,200-1,500 crore, said three people with direct knowledge of the development.
The move is aimed at creating the war chest to fund the expansion plan of the e-retailer through the inorganic route.
ounded by former Amazon employee Vishal Mehta a decade ago, Infibeam is the only listed and profitable ecommerce company in the country. The company offers a platfor m to vendors through its BuildaBazaar offering.
The move is aimed at creating the war chest to fund the expansion plan of the e-retailer through the inorganic route.
ounded by former Amazon employee Vishal Mehta a decade ago, Infibeam is the only listed and profitable ecommerce company in the country. The company offers a platfor m to vendors through its BuildaBazaar offering.
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Facebook Cracks Down on Static Images as Video and Fake Video Play Buttons with New Algorithm Update http://ow.ly/22Tm30euJdc #socialmedia
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