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About us
Creative Proteomics is the proteomics division of Creative Dynamics Inc, an integrated CRO company that provides a full range of drug development services, including Molecular Biology, Biochemistry, Systems Biology, Organic Chemistry, Genomics, Bioinformatics, Structural Biology, Preclinical and Clinical studies.

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Who’s Who: Threonine Versus Isothreonine
Combining retention models for peptide pairs with the relative peak intensity of the b-product ion in the HCD spectra unambiguously sorts peptide pairs containing threonine isoforms.

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A Novel Multiplex-Based, Nested Data-Independent Acquisition Method
Compared to conventional DIA, nested DIA used half the number of scans with shorter cycle times to achieve narrower mass isolation windows and product cleaner product ion spectra.
https://www.thermofisher.com/blog/proteomics/a-novel-multiplex-based-nested-data-independent-acquisition-method/
Instrumentation includes a Q Exactive Plus mass spectrometer.

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International Journal of Genomics, Proteomics, Metabolomics & Bioinformatics

For more detals : goo.gl/1J5SEp

#SciDocPublishers #SciDocPublishers_IJGPMB #Genomics #Proteomics #Metabolomics #Bioinformatics #Transcriptomics #MetabolomeResearch 
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Help for the lab computer ...

Crunch Next-Generation Mass Spectrometric Proteomic Data without Running out of Memory
Modifications to the OpenMS tool library including configuring random read access to the data disk and improved parsing speed to avoid constraints such as system memory result in faster proteomics data processing without heavy memory requirements.

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PREGO—A Tool for Building Better SRM Assays
PREGO, a software tool for predicting high-responding peptides, enables targeted SRM proteomics assay improvements of between 40% and 85% over previous approaches.
http://acceleratingscience.com/proteomics/prego-a-tool-for-building-better-srm-assays/

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Isoelectric Point Estimation, Amino Acid Sequence and Algorithms
Benchmarking algorithms for determining isoelectric points of peptides and proteins shows ideal conditions under which predictive tools work well for proteomics research.
http://acceleratingscience.com/proteomics/isoelectric-point-estimation-amino-acid-sequence-and-algorithms/

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Optimizing Search Engines and Post-Processing Approaches
Assessing post-processing methods highlights best search engine/filtering combinations for analyzing mass spectrometric proteomics data with highest accuracy.
http://acceleratingscience.com/proteomics/optimizing-search-engines-and-post-processing-approaches/

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Indigestion Relief with DIGESTIF
DIGESTIF, a soluble recombinant protein scaffold holding 11 artificial peptides, that gives researchers a way to monitor overall digestion during sample preparation for bottom-up proteomics studies.
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