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Moringa oleifera Seeds can clean water
Dr. Stephanie Velegol and colleagues recently published their work on explaining how a protein from the seeds of the Moringa oleifera tree can kill bacteria. It was known for some time that women in Egypt would use the seeds to clean dirty water. Since modern filtration systems are expensive and difficult to get to rural areas, understanding how the Moringa oleifera seeds work is important. Using cryo-TEM and simulations (among other techniques), they were able to demonstrate how the Moringa oleifera cationic protein (MOCP) kills bacteria. It fuses the inner and outer bacteria membranes.

☼ cryogenic electron microscopy (cryo-EM)
Cryo-EM (transmission EM in this case) is a technique where the sample is cryogenically frozen and then sliced for the EM scope. There are two main types of EM: transmission and scanning. In transmission EM, the electrons go through the sample. In scanning EM the electrons go over the sample. Unlike optical (common) microscopes, EM, as you probably guessed, use electrons instead of light. You can read more here:

☼ Simulations
Using data from multiple techniques, the researchers simulated what was going on with the MOCP and a test bacteria, E. coli. The data suggest that the MOCP cause flocculation and fusion of the inner and outer membranes.  Within 50 seconds the MOCP cause flocculation (like aggregation) of the bacteria. The simulations also suggest how the structure of the MOCP functions during the fusion process.

You can read the news blurb from Penn State here:

The full article is here (behind a paywall).
The Flocculating Cationic Polypetide from Moringa oleifera Seeds Damages Bacterial Cell Membranes by Causing Membrane Fusion.
Shebek K, Schantz AB, Sines I, Lauser K, Velegol S, Kumar M.
Langmuir. 2015 Apr 21;31(15):4496-502. doi: 10.1021/acs.langmuir.5b00015. Epub 2015 Apr 10.

h/t +Gnotic Pasta and +rasha kamel 
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Guess what I'm doing. 

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Here's some fantastic research we collaborated on. I'll write a little bit more about it when I have time.
Our collaborators, Dr. Stupp and Dr. Erin Hsu just published a paper about their research using a nanomaterial to promote bone growth. We did some of the microCT imaging and helped them with analysis. Congratulations to them.

Sulfated glycopeptide nanostructures for multipotent protein activation
S. Lee et al
Nature Nanotechnology (2017) doi:10.1038/nnano.2017.109
Accepted 28 April 2017 Published online 19 June 2017

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That's the pits
Did you know cherry pits are poisonous?

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Crazy on you
I think it's interesting that the prelude to this study was the finding that dogs that raise their eyebrows get adopted more than dogs that don't. Heck yeah, I want a doggo that makes facial expressions with their eyebrows. Cats, not so much. However, the more they rub on furniture or toys was more likely to get a cat adopted.

That means that, compared with dogs, cats haven’t faced as much evolutionary pressure to appeal to humans, the researchers say. In other words, cats are jerks. I keep trying to tell that to my cat friends. :)

As usual, ignore the title from Science Mag. The correct title is Crazy-faced cats don’t win the adoption game.

Here's your earworm.
Crazy on You by Heart.

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DNA research of dog breeds
It makes sense that a lot of small dogs share DNA with pugs. Pugs were often bred with larger dogs to produce smaller versions. When they get more breeds into this research, it might be worth getting my dog tested to see what the heck she is.

Ignore the incorrect title to the link

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Check out the #BIllMeetScienceTwitter hashtag on Twitter. Unfortunately I don't know the story behind the hashtag but I like seeing so many scientist on Twitter. It's also reassuring to see high visibility of female scientists.

Here's the story behind the hashtag.
This is a better link for background

The headline for the Forbes article is misleading.
A few scientists on Twitter decided Bill wasn't letting enough experts talk about science on his new Netflix show.

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This is really awesome and the photos are spectacular. I look forward to reading more about this nodosaur.
How about a dinosaur that is so well preserved that it “might have been walking around a couple of weeks ago,” as revealed in this spectacular find in Canada. Skin, scales and yes a face. “As it lumbered across the landscape between 110 million and 112 million years ago, almost midway through the Cretaceous period, the 18-foot-long, nearly 3,000-pound behemoth was the rhinoceros of its day.”

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Facts aren't optional.
It's one reason among many that I marched for science.

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Hey that's me in the red shirt (same shirt in my profile pic).

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