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Sherman Silber
Works at Infertility Center of Saint Louis
Attended Stanford University School of Medicine
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Sherman Silber

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Sherman Silber

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The Y chromosome contains 60 multicopy genes composed of nine different gene families concentrated in regions of multiple repeat sequences called amplicons arranged in mirror images called palindromes. This pattern is susceptible to deletions caused by homologous recombination with itself, and can explain the presence of small numbers of sperm in otherwise azoospermic men. [more]
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Sherman Silber

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Over the last 32 years, Sherman J Silber, M.D. has pioneered most of the "miracle" infertility treatments now accepted around the work for male and female infertility.
224 S. Woods Mill Road # 730S, St. Louis, MO 63017, USA
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Sherman Silber

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European researchers have linked strong ovarian stimulation in women aged over 35 to increased chromosomal abnormalities.

Genetic screening shows that the production of good quality oocytes in older women is disrupted during fertility treatment involving conventional ovarian stimulation. This process uses hormones to promote the release of a greater number of oocytes than normal and, in general, larger doses are given to women over 35, who need more help producing eggs.
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People
Have him in circles
96 people
Tuhin Adhikary's profile photo
kim jensen's profile photo
Liliya Tyndyk's profile photo
Work
Occupation
Renowned pioneer in microsurgery and infertility
Employment
  • Infertility Center of Saint Louis
    present
Basic Information
Gender
Male
Other names
Dr. Sherman J. Silber, Sherman Silber, Dr. Silber
Story
Tagline
Over the last 35 years, Sherman J. Silber, M.D., has pioneered most of the “miracle” infertility treatments now accepted around the world for male as well as female infertility. These breakthroughs include microscopic vasectomy reversal, tubal ligation reversal, ICSI (intra-cytoplasmic sperm injection), male infertility and improving success rates with IVF (in vitro fertilization), reducing IVF costs and eliminating complications. Other areas include: egg freezing to preserve fertility, ovary transplantation and preserving fertility in cancer patients.
Introduction

Dr. Sherman Silber, a renowned pioneer in microsurgery and infertility, is considered one of the world’s leading authorities on IVF, mini-IVF,sperm retrieval , ICSI, vasectomy reversal, male infertility, tubal ligation reversal, egg and embryo freezing, ovary transplantation, and thereproductive biological clock. He performed the world’s first microsurgical vasectomy reversal, as well as the first testicle transplant, in the 70’s and now in the current century, the world’s first ovary transplant. He was the first to develop the TESE and MESA techniques for retrieving testicular and epididymal sperm in azoospermic men. He headed the clinical MIT team that first mapped and sequenced the Y chromosome in infertile men and discovered the now famous DAZ gene for male fertility. His research includes also the study of reproduction and fertility in zoo animals and endangered species. Most recently he has perfected the preservation of fertility for cancer patients with ovarian freezing and transplantation and thereby figured out how to extend the reproductive biological clock of women. He has helped pioneer minimal ovarian stimulation to reduce IVF Costs. He has even recently answered the age-old question of why the dinosaurs went extinct by extending his research on male infertility and the Y chromosome, discovering that the change in earth temperature 65,000,000 years ago led to the birth of a skewed male/female sex ratio.

Dr. Silber has treated many thousands of infertile couples who travel to St. Louis daily from all over the world. His patients come from every state in the U.S.A., all over Europe, South America, the Middle East, Asia, and Africa. His patients include doctors, teachers, rock stars, secretaries, politicians, astronauts, movie stars, scientists, truck drivers, lawyers, migrant fruit pickers, CEO’s, princes and kings.
Bragging rights
He is the author of three medical textbooks, five best-selling books for the layman and more than 200 scientific papers on human infertility and reproduction. His most recent book, “How to Get Pregnant”, published by Little, Brown and Company in 2007, is a completely revised and updated edition of his classic series of “How To Get Pregnant” books, which have been major bestsellers in the United States. Dr. Silber’s books have been published in English, Spanish, German, and Russian. He has appeared on the Donahue Show, Gary Collins, Peter Jennings ABC Nightly News, Oprah, Charlie Rose and Ted Koppel Nightline. He has been a consultant numerous times on the Joan River Show and ABC News, and has been a regular contributor many times on CNN, KMOX, WOR, and NPR radio.
Education
  • Stanford University School of Medicine
  • University of Michigan
Contact Information
Work
Phone
314-576-1400
Email