(A new research file citation dump: #longevity #cancer #diet #caloric #restriction #mortality
L Yan, R. F. Lamb. Amino acid sensing and regulation of mTORC1. Semin Cell Dev Biol. 2012 23(6):621 - 625.
X Wang, C G Proud. Nutrient control of TORC1, a cell-cycle regulator. Trends Cell Biol. 2009 19(6):260 - 267.
SH Lee, KJ Min. Caloric restriction and its mimetics. BMB Rep. 2013 46(4):181-187.
K Morris, American Nursing Association. Live long and prosper. Ohio Nurses Rev. 2013 88(4):10-11, 13.
SC Johnson, PS Rabinovitch, M Kaeberlein. mTOR is a key modulator of ageing and age-related disease. Nature. 2013 493(7432):338 - 345.
S Davinelli, DC Willcox, G. Scapagnini. Extending healthy ageing: nutrient sensitive pathway and centenarian population. Immun. Ageing. 2012 9:9.
SJ Simpson, D Raubenheimer. Macronutrient balance and lifespan. Aging (Albany NY). 2009 1(10):875 - 880.
J Gallinetti, E Harputlugil, JR Mitchell. Amino acid sensing in dietary-restriction-mediated longevity: Roles of signal-transducing kinases GCN2 and TOR. Biochem J. 2013 449(1):1 - 10.
S Nakagawa, M Lagisz, KL Hector, HG Spencer. Comparative and meta-analytic insights into life extension via dietary restriction. Aging Cell. 2012 11(3):401 - 409.
UN Das. When less is adequate: Protein and calorie restriction boosts immunity and possibly, longevity--but how and why? Nutrition. 2009 25(9):892 - 895.
L Fontana, L Partridge, VD Longo. Extending healthy life span--from yeast to humans. Science. 2010 328(5976):321 - 326.
DC Willcox, BJ Willcox, H Todoriki, M Suzuki. The Okinawan diet: health implications of a low-calorie, nutrient-dense, antioxidant-rich dietary pattern low in glycemic load. J Am Coll Nutr. 2009 28 (Suppl 500S - 516S).
B J Willcox, D C Willcox, H Todoriki, A Fujiyoshi, K Yano, Q He, J D Curb, M Suzuki. Caloric restriction, the traditional Okinawan diet, and healthy aging: the diet of the world's longest-lived people and its potential impact on morbidity and life span. Ann. NY Acad Sci. 2007 1114(1):434 - 455.
R Pallavi, M Giorgio, P G Pelicci. Insights into the beneficial effect of caloric/ dietary restriction for a healthy and prolonged life. Front Physiol. 2012 3:318.
A J Dirks, C Leeuwenburgh. Caloric restriction in humans: potential pitfalls and health concerns. Mech. Ageing Dev. 2006 127(1):1 - 7.
B C Melnik. Leucine signalling in the pathogenesis of type 2 diabetes and obesity. World J Diabetes. 2012 3(3):38 - 53.
M F McCarty. mTORC1 activity as a determinant of cancer risk--rationalizing the cancer-preventive effects of adiponectin, metformin, rapamycin, and low-protein vegan diets. Med Hypotheses 2011 77(4):642 - 648.
G E Fraser, D J Shavlik. Ten years of life: Is it a matter of choice? Arch Intern Med. 2001 161(13):1645 - 1652.
V. Agrawal, S. E. J. Alpini, E. M. Stone, E. P. Frenkel, A. E. Frankel. Targeting methionine auxotrophy in cancer: discovery & exploration. Expert Opin Biol Ther 2012 12(1):53 - 61.
M. F. McCarty, J. Barroso-Aranda, F. Contreras. The low-methionine content of vegan diets may make methionine restriction feasible as a life extension strategy. Med. Hypotheses 2009 72(2):125 - 128.
M. C. Ruiz, V. Ayala, M. Portero-Otín, J. R. Requena, G. Barja, R. Pamplona. Protein methionine content and MDA-lysine adducts are inversely related to maximum life span in the heart of mammals. Mech. Ageing Dev. 2005 126(10):1106 - 1114.
M. López-Torres, G. Barja. Lowered methionine ingestion as responsible for the decrease in rodent mitochondrial oxidative stress in protein and dietary restriction possible implications for humans. Biochim. Biophys. Acta 2008 1780(11):1337 - 1347.
E. Cohen. Chitin synthesis and degradation as targets for pesticide action. Arch. Insect Biochem. Physiol. 1993 22(1 - 2):245 - 261.
P. Cavuoto, M. F. Fenech. A review of methionine dependency and the role of methionine restriction in cancer growth control and life-span extension. Cancer Treat. Rev. 2012 38(6):726 - 736.
E. Boedeker, G. Friedel, T. Walles. Sniffer dogs as part of a bimodal bionic research approach to develop a lung cancer screening. Interact Cardiovasc Thorac Surg 2012 14(5):511 - 515.
H. Sonoda, S. Kohnoe, T. Yamazato, Y. Satoh, G. Morizono, K. Shikata, M. Morita, A. Watanabe, M. Morita, Y. Kakeji, F. Inoue, Y. Maehara. Colorectal cancer screening with odour material by canine scent detection. Gut 2011 60(6):814 - 819.
K. Yamagishi, K. Onuma, Y. Chiba, S. Yagi, S. Aoki, T. Sato, Y. Sugawara, N. Hosoya, Y. Saeki, M. Takahashi, M. Fuji, T. Ohsaka, T. Okajima, K. Akita, T. Suzuki, P. Senawongse, A. Urushiyama, K. Kawai, H. Shoun, Y. Ishii, H. Ishikawa, S. Sugiyama, M. Nakajima, M. Tsuboi, T. Yamanaka. Generation of gaseous sulfur-containing compounds in tumour tissue and suppression of gas diffusion as an antitumour treatment. Gut 2012 61(4):554 - 561.
H. Y. Guo, H. Herrera, A. Groce, R. M. Hoffman. Expression of the biochemical defect of methionine dependence in fresh patient tumors in primary histoculture. Cancer Res. 1993 53(11):2479 - 2483.
D. E. Epner. Can dietary methionine restriction increase the effectiveness of chemotherapy in treatment of advanced cancer? J Am Coll Nutr 2001 20(Suppl 5):443S-449S; discussion 473S-475S.
E. Cellarier, X. Durando, M. P. Vasson, M. C. Farges, A. Demiden, J. C. Maurizis, J. C. Madelmont, P. Chollet. Methionine dependency and cancer treatment. Cancer Treat. Rev. 2003 29(6):489 - 499.
B. C. Halpern, B. R. Clark, D. N. Hardy, R. M. Halpern, R. A. Smith. The effect of replacement of methionine by homocystine on survival of malignant and normal adult mammalian cells in culture. Proc. Natl. Acad. Sci. USA 1974 71(4):1133 - 1136.
C. M. Willis, S. M. Church, C. M. Guest, W. A. Cook, N. McCarthy, A. J. Bransbury, M. R. T. Church, J. C. T. Church. Olfactory detection of human bladder cancer by dogs: Proof of principle study. BMJ 2004 329(7468):712.
D. Pickel, G. P. Manucy, D. B. Walker, S. B. Hall, J. C. Walker. Evidence for canine olfactory detection of melanoma. App Anim Behav Sci 2004 89(1):107-116. #cancer #caloric #restriction #fasting #methionine