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Laurence A. “Larry” Moran
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1,281 followers
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Who wants "A Sad Case: Owen vs Huxley" pamphlet and a possible Darwin letter?
A friend has a neighbor who's in possession of a pamphlet from 1868 on the Owen vs Huxley debate. The text of the pamphlet is here: A Report of A SAD CASE, Recently tried before the Lord Mayor, OWEN versus HUXLEY, In which will be found fully given the Meri...
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How many protein-coding genes in the human genome?
The three main human databases (GENCODE/Ensembl, RefSeq, UniProtKB) contain a total of 22,210 protein-coding genes but only 19,446 of these genes are found in all three databases. That leaves 2764 potential genes that may or may not be real. A recent public...
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Nature falls (again) for gene hype
Nature is arguably the most prestigious science journal. Articles published in Nature are widely perceived to be correct, unbiased, and factual. This perception is certainly true of articles that appear in the News section of the journal since these article...
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Disappearing genes: a paper is refuted before it is even published
Several readers alerted me to a paper that was posted on bioRxiv a few weeks ago (May 28, 2018). The paper claimed that the human genome contains 43,162 genes consisting of 21,306 protein-coding genes and 21,856 noncoding genes. The authors reported that th...
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Press release from the Francis Crick Institute misrepresents junk DNA
Press releases have become a serious problem. I'm frequently upset whenever I read a press release covering a field I'm familiar with. They rarely do a good job of explaining what's actually in the paper and putting it into the proper context. The people wh...
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Another contribution of philosophy: Bernard Lonergan
The discussion about philosophy continues on Facebook. One of my long-time Facebook friends, Jonathan Bernier, took up the challenge. Bernier is a professor of religious studies at St. Francis Xavier University in Nova Scotia, Canada. He is a card-carrying ...
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Another contribution of philosphy: Bernard Lonergan
The discussion about philosophy continues on Facebook. One of my long-time Facebook friends, Jonathan Bernier, took up the challenge. Bernier is a professor of religious studies at St. Francis Xavier University in Nova Scotia, Canada. He is a card-carrying ...
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Contributions of philosophy
I've been discussing the contributions of philosophy on Facebook. Somebody linked to a a post on the topic: What has philosophy contributed to society in the past 50 years? . Here's one of contributions ... do you agree? Philosophers, historians, and sociol...
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Confusion about the number of genes
My last post was about confusion over the sizes of the human and mouse genomes based on a recent paper by Breschi et al. (2017). Their statements about the number of genes in those species are also confusing. Here's what they say about the human genome. [Ac...
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Genome size confusion
The July 2017 issue of Nature Reviews: Genetics contains an interesting review of a topic that greatly interest me. Breschi, A., Gingeras, T. R., and Guigó, R. (2017). Comparative transcriptomics in human and mouse. Nature Reviews Genetics [ doi: 10.1038/nr...
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