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Laurence A. “Larry” Moran
1,274 followers
1,274 followers
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Laurence A. “Larry” Moran's posts

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Another contribution of philosophy: Bernard Lonergan
The discussion about philosophy continues on Facebook. One of my long-time Facebook friends, Jonathan Bernier, took up the challenge. Bernier is a professor of religious studies at St. Francis Xavier University in Nova Scotia, Canada. He is a card-carrying ...

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Another contribution of philosphy: Bernard Lonergan
The discussion about philosophy continues on Facebook. One of my long-time Facebook friends, Jonathan Bernier, took up the challenge. Bernier is a professor of religious studies at St. Francis Xavier University in Nova Scotia, Canada. He is a card-carrying ...

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Contributions of philosophy
I've been discussing the contributions of philosophy on Facebook. Somebody linked to a a post on the topic: What has philosophy contributed to society in the past 50 years? . Here's one of contributions ... do you agree? Philosophers, historians, and sociol...

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Confusion about the number of genes
My last post was about confusion over the sizes of the human and mouse genomes based on a recent paper by Breschi et al. (2017). Their statements about the number of genes in those species are also confusing. Here's what they say about the human genome. [Ac...

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Genome size confusion
The July 2017 issue of Nature Reviews: Genetics contains an interesting review of a topic that greatly interest me. Breschi, A., Gingeras, T. R., and Guigó, R. (2017). Comparative transcriptomics in human and mouse. Nature Reviews Genetics [ doi: 10.1038/nr...

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Debating alternative splicing (Part IV)
In Debating alternative splicing (Part III) I discussed a review published in the February 2017 issue of Trends in Biochemical Sciences . The review examined the data on detecting predicted protein isoforms and concluded that there was little evidence they ...

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Dedbating alternative splicing (Part IV)
In Debating alternative splicing (Part III) I discussed a review published in the February 2017 issue of Trends in Biochemical Sciences . The review examined the data on detecting predicted protein isoforms and concluded that there was little evidence they ...

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Debating alternative splicing (Part III)
Proponents of massive alternative splicing argue that most human genes produce many different protein isoforms. According to these scientists, this means that humans can make about 100,000 different proteins from only ~20,000 protein-coding genes. They tend...

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Debating alternative splicing (part II)
Mammalian genomes are very large. It looks like 90% of it is junk DNA. These genomes are pervasively transcribed, meaning that almost 90% of the bases are complementary to a transcript produced at some time during development. I think most of those transcri...

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Debating alternative splicing
I recently had a chance to talk science with my old friend and colleague Jack Greenblatt . He has recently teamed up with some of my other colleagues at the University of Toronto to publish a paper on alternative splicing in mouse cells. Over the years I ha...
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