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Ward Plunet
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59,509 followers
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*CRISPR gene editing makes stem cells 'invisible' to immune system
by University of California, San Francisco*

UC San Francisco scientists have used the CRISPR-Cas9 gene-editing system to create the first pluripotent stem cells that are functionally "invisible" to the immune system, a feat of biological engineering that, in laboratory studies, prevented rejection of stem cell transplants. Because these "universal" stem cells can be manufactured more efficiently than stem cells tailor-made for each patient—the individualized approach that dominated earlier efforts—they bring the promise of regenerative medicine a step closer to reality.
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Dog burial as common ritual in Neolithic populations of north-eastern Iberian Peninsula

Coinciding with the Pit Grave culture (4200-3600 years before our era), coming from Southern Europe, the Neolithic communities of the north-eastern Iberian Peninsula started a ceremonial activity related to the sacrifice and burial of dogs. The high amount of cases that are recorded in Catalonia suggests it was a general practice and it proves the tight relationship between humans and these animals, which, apart from being buried next to them, were fed a similar diet to humans'.
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Get fit for a fit gut: Exercise might improve health by increasing gut bacterial diversity

Bacteria, often synonymous with infection and disease, may have an unfair reputation. Research indicates there are as many, if not more, bacterial cells in our bodies as human cells, meaning they play an important role in our physiology. In fact, a growing body of evidence shows that greater gut microbiota diversity (the number of different species and evenness of these species' populations) is related to better health. Now, research published in Experimental Physiology has suggested that the efficiency with which we transport oxygen to our tissues (cardiorespiratory fitness) is a far greater predictor of gut microbiota diversity than either body fat percentage or general physical activity.
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'Lack of cleaning' in brain cells is central to Alzheimer's disease

An international research team has created a better understanding of Alzheimer's. They have shown that the cleaning system of the brain cells, the so-called mitophagy, is very weakened in animals and humans with Alzheimer's. And when they improve the cleaning system in the animals, the Alzheimer's symptoms almost disappear.
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Future pills will be personalized and 3D printed, just for you

Meet the scientists using 3D printers to deliver safer, more effective tablets for children.
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Healthy diet can ease symptoms of depression

An analysis of data from almost 46,000 people has found that weight loss, nutrient boosting and fat reduction diets can all reduce the symptoms of depression. Dr. Joseph Firth, an Honorary Research fellow at The University of Manchester and Research Fellow at NICM Health Research Institute at Western Sydney University, says existing research has been unable to definitively establish if dietary improvement could benefit mental health. But in a new study published in Psychosomatic Medicine, Dr. Firth and colleagues brought together all existing data from clinical trials of diets for mental health conditions. And the study provides convincing evidence that dietary improvement significantly reduces symptoms of depression, even in people without diagnosed depressive disorders.
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Fasting ramps up human metabolism, study shows

Research uncovers previously unknown effects of fasting, including notably increased metabolic activity and possible anti-aging effects.
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Study shows blocking serotonin receptors blocks mind-altering effects of LSD

An international team of researchers has found that blocking serotonin receptors in the brain blocks LSD's mind-altering effects. In their paper published in Proceedings of the National Academy of Sciences, the group describes experiments they carried out on volunteers given LSD and what they found.
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Engineers translate brain signals directly into speech

In a scientific first, neuroengineers have created a system that translates thought into intelligible, recognizable speech. This breakthrough, which harnesses the power of speech synthesizers and artificial intelligence, could lead to new ways for computers to communicate directly with the brain. It also lays the groundwork for helping people who cannot speak, such as those living with as ALS or recovering from stroke, regain their ability to communicate with the outside world.
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Energizing the immune system to eat cancer

Researchers say they've identified how to fuel macrophages with the energy needed to attack and eat cancer cells.
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