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Tony Renzaglia
21 followers -
Hard work and determination are at my core.
Hard work and determination are at my core.

21 followers
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New drug protects against radiation induced damage and death 
People may get exposed to damaging radiation after a nuclear accident (or war) or as part of irradiation for cancer therapy and a drug that protects people from its damaging effects has been sought for a long time and one of the candidates that had shown promise was lysophosphatidic acid or LPA which was a lipid which brought in practical problems. Scientists studying the mechanism by which LPA gave protection have created a synthetic drug that does the trick. LPA acts through its receptor LPA2 and activates a signaling cascade that activates a DNA repair pathway and also inhibits caspase mediated apoptosis allowing for the cells to survive otherwise lethal doses of irradiation. The drug worked even when given 72 hours after radiation exposure. While 13/14 mice died in the untreated group, only one died in the arm receiving DBIB. 
The drug would be of potential in treating victims of accidental radiation injury and radiation toxicity after radiotherapy, if it survives human studies. #radiationppoisoning   #radiationprotection  Combined Mitigation of the Gastrointestinal and Hematopoietic Acute Radiation Syndromes by an LPA2 Receptor-Specific Nonlipid Agonist http://goo.gl/JHXRoj
Commentary in new scientist Anti-radiation drug could work days after exposure   http://goo.gl/fKxM75
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"Mastering others is strength.Mastering yourself is true power"
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One of the beautiful places I have seen in Canadian Rockies and less traveled by visitors.
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Clean eating and hard training results in just 50 days!
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