When antibiotics came on the scene beginning with the discovery of Penicillin, they were revolutionary saving the lives of millions and creating an albeit short lived visions of conquering deadly infectious diseases. With widespread use and often misuse with the most infamous being the widespread use of antibiotics as "growth promoters" for farm animals, the scourge of antibiotic resistance was an evolutionary certainty. After all most antibiotics (the lead molecules) existed in nature we stumbled on them and they were produced by environmental microbes (mostly fungi or streptomyces) to gain advantage over other microbes. Introduce sufficient selection pressures as would happen with widespread use in cattle feed, emergence of widespread resistance was natural.
We have reached a situation, this is no longer isolated cases in remote places but a reality all over the world. If you are struck with a deadly resistant strain, there is little any one can do. In a competitive world driven by economics, global action is needed to control misuse of antibiotics and curtail their spread while increasing public funding for development of new classes of antibiotics.
Significant part of the problem is the lack of investment in developing new antibiotics. Big pharmaceutical companies see little profit in antimicrobial. They would rather invest in money spinning sector like chronic lifestyle diseases or cancer where opportunities to extract ransom are greater. Here Mark Woolhouse and Jeremy Farrar call for an intergovernmental panel to coordinate global efforts in tackling this scourge. #antimicrobialresistance #policy #WHO