Another great article. People ask me all the time what type of low end speakers I check my sounds on. The answer is, I don't. I design my sounds on my reference monitors that I'm comfortable with and that's it. I never get any complaints, so I guess it works.
I heard a great quote once at GDC, can't remember who said it, but it was referring to targeting people with low-end sound sounds; "If you don't care about audio, then I don't care about you."