Immediately before the ASCPT 2017 Annual Meeting, the International Transporter Consortium (ITC) will host its third workshop focusing on new research in membrane transporters, particularly as they relate to drug development. This workshop will take place on March 13-14, 2017, at the Omni Shoreham Hotel in Washington, DC. Research on membrane transporters has exploded, with approximately half of all scientific research articles on transporters published within the last 10 years. Increasingly, drug developers are interested in transporters as mediators of clinically important drug-drug interactions, and as pharmacologically relevant targets. The ITC continues to play a leading role in informing drug development strategies and regulatory sciences, especially relevant to drug-drug interactions. The ‘Third Workshop on Membrane Transporters in Drug Development’ is a two-day workshop, with speakers who are world-class transporter biologists from universities, regulatory agencies and pharmaceutical companies. The workshop will cover a range of topics in transporter biology, including the endogenous function of transporters, emerging transporters of importance in drug development, computational modeling, genomics and biomarker probes of transporters. As always, one of the most exciting parts of the workshop will be its concluding session on regulatory issues in transporter-mediated drug-drug interactions. Case studies representing perspectives of regulatory agencies (e.g., FDA and EMA) will be presented along with a panel discussion involving experts in the field to address questions from the attendees. Finally, there will be breakout groups of interested scientists who will focus on writing whitepapers and review articles to be published in a special issue of Clinical Pharmacology & Therapeutics.

Kathleen M. Giacomini, Lawrence Lin, Kim Brouwer, Aleksandra Galetin, Shiew-Mei Huang, Pär Matsson, Nilay Thakkar, Maciej X. Zamek-Gliszczynski, Lei Zhang, and Donald Tweedie
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