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John Garner
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65 followers
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mPEG-PLGA and PLGA from PolySciTech used in development of nanoparticle combination therapy for brain-cancer treatment
Glioblastoma is a form of brain-cancer that is highly aggressive with a 15-16 month median patient survival rate. Use of nanoparticles which may cross the blood-brain-barrier, along with combination therapeutic approaches, may provide further treatment opti...
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Block-copolymers from PolySciTech used in the development of nano-emulsion based ultra-sound mediated noninvasive targeted drug delivery
Due to the circulatory nature of the human bloodstream, any agent introduced into the bloodstream at any location is quickly spread throughout the human body. This is good for drugs which need to be spread throughout the human body (i.e. systemic dosage) ho...
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PLGA from PolySciTech used in development of mixing system for rapid generation of nanoparticles
Nanoparticles are generally created by a controlled nanoprecipitation of polymer into a non-solvent. There are many different ways to generate nanoparticles which fundamentally differ mostly on how the mixing of polymer solution and non-solvent is accomplis...
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PLGA from PolySciTech used in developing DP44mt loaded nanoparticles for cancer therapy against resistant cancers
DP44mt is a chelator molecule that binds iron and removes it from the intracellular environment. In cancer cells, this agent acts to induce cancer-cell death through upregulation of AMPK pathway and through corrupting autophagic mechanisms. One of the benef...
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Get ‘Bezwa-more’ for your Bezwada-branded product purchase placed through PolySciTech with discount code BEZWADA40
In addition to in-house manufactured materials, PolySciTech also carries products by high-quality suppliers with a focus on biomedical and polymer products. Starting from November 8 through December 31, receive an additional 40% discount off the price of Be...
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mPEG-PLA and PLA-PEG-COOH from PolySciTech used in the development of nanoparticles to treat colon cancer
Galbanic acid is a naturally occurring compound extracted from Ferula (wild carrots) which has potent activity against cancer, as well as anticoagulative, antiviral, and antibacterial properties. Despite its promising biological activity, it has very poor w...
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PLGA from PolySciTech used in development of nanoparticle therapy against non-small cell lung cancer
Non-small cell lung cancer is an extremely common form of cancer, leading to more than 200,000 cases in USA per year. This type of cancer typically responds poorly to chemotherapy and often becomes resistant against many chemotherapeutics. Recently, resear...
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Fluorescent PLGA-rhodamine from PolySciTech used in development of siRNA nanoparticle therapy against glaucoma
Glaucoma is a progressive disease which damages the eye’s optic nerves eventually leading to blindness if left untreated. The overgrowth of connective tissue (e.g. non-nerve based tissue for mechanical strength) is affiliated with the progression of this di...
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PLGA from PolySciTech used in creation of near-IR light responsive nanoparticles for cancer therapy
Near-infrared light (wavelength between 700-1000 nm, for example T.V. remote control wavelength) has the ability to penetrate through human skin. Although this wavelength, by itself, has no therapeutic effect, it has the ability to trigger specifically desi...
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