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Steve Trutane
Works at Personalis, Inc.
Attended University of Colorado, Boulder
Lives in Albany, CA
119 followers|163,967 views
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Steve Trutane

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Cool 3D graphic navigation of the El Cap route by page scrolling. A must-see for +Mark Pratt 
A graphic tracks at attempt by Tommy Caldwell and Kevin Jorgeson to free-climb the 3,000-foot Dawn Wall, a vertical sheet of mostly smooth granite that many believe is the hardest climb in the world.
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very cool!
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Amazing what can be done with whole exome variant analysis these days :)
 
Here's a great new paper on Clinical #Genetics (by Anne M. Slavotinek, et. al.) on how augmented #exome #sequencing identifies the genetic causes of eye defects. Please visit www.personalis.com/clinical to learn more.
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Surprising that "Clinical applicability" got such a low ranking in the survey, yet article is all about clinical. Wondering what audience was targeted by the survey?
Sequencing the human genome the first time cost $3 billion and took 13 years to complete. That was in 2003. Eleven years later, next-generation sequencing technology has brought the single-genome price close to $1000 and cut the time to days. These advances have enabled new opportunities for ...
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"The truth is, Page is probably right about the underlying opportunity.  In particular, as I’ve long-argued, there’s tremendous potential to be found by thoughtfully combining comprehensive genomic and rich phenotypic data – immediate opportunities to impact clinical care, and the chance for a longer-term impact on scientific understanding."
“Generally, health is just so heavily regulated. It's just a painful business to be in. It's just not necessarily how I want to spend my time. Even though we do have some health projects, and we'll be doing that to a certain extent. But I think the regulatory burden in the U.S. is so high that think it would dissuade a lot of entrepreneurs.”
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 #UV
 
"The concept that we would have a pathway in our skin that is organically guiding us to to seek out the most common carcinogen in the world almost seems like a joke... From a scientific perspective, this raises an interesting prospect that perhaps UV-seeking was the original addiction."


In studying how ultraviolet radiation affects skin, scientists may have stumbled across humankind's original addiction: sunlight. A new study in the journal Cell shows that UV radiation, even in modest amounts, prompts production of the "feel...
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Steve Trutane

commented on a video on YouTube.
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Full show is at http://video.gpb.org/video/2365240520/ 

Alzheimer's research got a shot in the arm today: Emory Awarded $7.2M from NIA for Proteomic Research into Alzheimer's (10 Jun 2014) http://www.genomeweb.com//node/1400751

"Applying a systems biology approach, we will be able to pinpoint those proteins which are most central to the network of complex changes in the brain, which ones are most likely to first trigger the disease years before the onset of any symptoms, and hence, which ones are the most promising new targets for developing preventive therapies."
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Steve Trutane

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Problems created by rogue open access "journals" -- tho not PLoS, mind.

"Scientists view this industry as a problem for a few reasons: it reduces trust in science, allows unqualified researchers to build their resumes with fake or unreliable work, and makes research for legitimate scientists more difficult, as they're forced to wade through dozens of worthless papers to find useful ones."
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"Aristotelian 'science' was a major setback for all of human civilization. For Aristotle, science started with empirical investigation and then used theoretical speculation to decide what things are caused by.

What we now know as the 'scientific revolution' was a repudiation of Aristotle: science, not as knowledge of the ultimate causes of things but as the production of reliable predictive rules through controlled experimentation."
Intellectuals of all persuasions love to claim the banner of science. A vanishing few do so properly.
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Other mass medical and genomics studies exist. But Baseline will amass a much larger and broader set of new data. The hope is that this will help researchers detect killers such as heart disease and cancer far earlier, pushing medicine more toward prevention rather than the treatment of illness.

The project won't be restricted to specific diseases, and it will collect hundreds of different samples using a wide variety of new diagnostic tools. Then Google will use its massive computing power to find patterns, or "biomarkers," buried in the information. The hope is that these biomarkers can be used by medical researchers to detect any disease a lot earlier.
Called Baseline Study, Google's project will gather anonymous genetic and molecular information to create a full picture of what a healthy human is.
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Breakdancing in the BART Transbay tube.
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Puya Raimondii - bloom could be 30ft tall with 30k flowers.
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"This surgical technique replaces all of a patient's blood with saline at 10°C (50°F)  to chill the body and buy time for doctors to fix injuries without losing patients to blood loss.... Normally, we can't survive with our blood missing. However, when body temp is very low, cellular activity stops and cells survive without oxygen, thus preventing further damage to tissues and organs."
A new human trial will chill gunshot victims to keep them alive
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People
Have him in circles
119 people
Ramon Rovira Angrill's profile photo
Sean McFarland's profile photo
eleanore adams's profile photo
Michael Reich's profile photo
Kelly Keller's profile photo
Randi Chervitz's profile photo
Strawberry Canyon Track Club's profile photo
John Matese's profile photo
Atul Butte's profile photo
Work
Occupation
Computational Biologist/Bioinformatician
Employment
  • Personalis, Inc.
    Senior Bioinformatics Scientist, 2012 - present
  • FGED Society
    Secretary, Webmaster, 2010 - present
  • TeamHuman.org
    Founder, 2009 - present
  • Omicia, Inc
    Computational Biologist, 2010 - 2012
  • Affymetrix, Inc.
    Bioinformatics Engineer, 2000 - 2010
  • Neomorphic Software
    Software Engineer, 1998 - 2000
Places
Map of the places this user has livedMap of the places this user has livedMap of the places this user has lived
Currently
Albany, CA
Previously
St. Louis, MO - Boulder, CO - St. Paul, MN
Story
Introduction
See my Wikipedia user page for details: http://en.wikipedia.org/wiki/User:SteveChervitzTrutane
Bragging rights
Founder of TeamHuman.org. Genome biologist programmer, wikipedian, triathlete, and father of two. Sporadic blogger but more frequent tweeter (@trutane). Other haunts: LinkedIn (stevechervitz), old delicious links (delicious.com/trutane)
Education
  • University of Colorado, Boulder
    Molecular, Cellular, Developmental Biology, 1987 - 1995
  • Macalester College
    Biology & Philosophy, 1983 - 1987
  • Parkway West Senior High
    1980 - 1983
Basic Information
Gender
Male
Other names
Chervitz