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NanoBiotech Pharma
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NanoBiotech Pharma - Innovative, Revolutionary & Pioneering
NanoBiotech Pharma - Innovative, Revolutionary & Pioneering

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NANOBIOTECH PHARMA is pleased to announce the addition of Aubrey de Grey,PhD to our Medical Advisory Committee. Aubrey is arguably the World's most renowned gerontologist/antiaging expert. He is Chief Science Officer at the SENS Foundation & Methuselah Foundation. We look forward to working closely with Aubrey in our regenerative medicine R&D with NanobacTX & his SENS Foundation. When not on his whirlwind Worldwide antiaging lecturing circuit, lecturing on antiaging, Dr. de Grey splits his time as a Professor at Cambridge University in the UK and as the Chief Science Officer at the SENS Foundation in Mountain View, CA. Other recent MAC additions are Terry Grossman,MD; Daniel Shoskes,MD; Erik Noji,MD,MPH; Jeremy Stone,MD,MBA; David Goldsmith,MD,PhD; Marshall Stoller,MD; Daniel Shoskes,MD & Patrick Fratellone,MD,FACC. More at www.NanoBiotechPharma.com
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7 WOMEN’S FACTS for National Heart Month 

1) Women develop Heart Disease after Menopause begins.
Women naturally have more of the female hormone Estrogen than do men, and Estrogen has several heart-protective effects. During the female climacteric of menopause the ovaries stop producing estrogen. This is when the cardio-protective functions of estrogen stop. Post-Menopausal changes are not limited to just the hormone change, but rather extend to weight gain, high blood pressure and decreases of the “good” cholesterol HDL. HDL is cardioprotective because it binds endotoxin and thereby decreases inflammation. All of these changes herald the beginning of heart disease in Women and they develop coronary disease rapidly after menopause….catching-up and sometimes passing men in the development of coronary artery disease plaque…….not good. 

2) Women ‘s Chest Pain Symptoms are More Subtle and Commonly Ignored.
Although women often have a dramatic onset of symptoms, such as numbness or a sharp pain in the middle, left, or right side of the chest, these symptoms are commonly dismissed as nervousness, anxiety, stress, or indigestion. Women’s Signs of coronary artery disease (CAD) include discomfort in the chest, waking up at night with difficulty catching breath; chronic generalized fatigue; a pain below the left shoulder blade or elsewhere in the back; toothache-like symptoms felt in the neck, pain or tingling in jaw, elbow, or arm; a pain in the left arm simultaneous with chest pain; throat tightness; shortness of breath; heartburn-like problems accompanied by a feeling of fullness and wanting to burp; nausea and vomiting; lightheadedness, dizziness, or dizziness with exertion; heavy sweating with activity; angina; or heart attack.

3) The Female Heart is built differently.
Men's hearts are larger, with more powerful muscles, used to bearing a sudden increase in workload. Women’s hearts are smaller, and the arteries are narrower. Because the inside diameter of the arteries is narrower, they can be blocked more easily by a buildup of calcified coronary artery plaque (CAD).

4) Women’s Angina Chest Pain is Different than Men’s.
Men's angina comes on with exercise or exertion, and improves with rest. Women's angina comes and goes with no obvious cause, and may not improve with rest. Women's angina is often mistaken for gastrointestinal problems. Women experience chronic lower-grade angina symptoms rather than sudden dramatic signs.

5) Heart problem causes are more than medical for women.
Women are more likely to downplay and generalize stress and unhappiness as heart problems, but also more intuitive about diagnosing the problem. For men, heart problems may present themselves in fairly mechanical terms, making it possible to treat the symptoms as they appear. Women’s symptoms are more insidious and are often accompanied with problems of the heart, of the fullness of their emotional life. 

6) Hormone Replacement Therapy should also begin as Menopause arrives.
Women’s hormone replacement therapy can help delay the rapid development of CAD heart plaque that would aggressively begin after menopause. Menopause can occur as early as age 35, or after removal of the ovaries. The “usual” onset of Menopause is around age 45-50. CAD and heart disease plaque begins when we are born and continues all of our lives….EVEN IN WOMEN. But Women develop CAD more slowly than do Men…ONLY UNTIL MENOPAUSE. But after menopause, Women’s CAD develops rapidly.

7) Women need NanobacTX to improve their heart health. Women also need Estrogen replacement at menopause to allay aggressive development of CAD.
Estrogen replacement therapy is in 3 forms: Prescription Estrogen, Bio-Identical Estrogen (usually from plants) and Tibolone. Tibolone is not yet FDA approved in the USA, but has been successfully used in the rest of the World for nearly 25 years and superior to the current products available in the US. NanobacTX is non-prescription and available at http://www.nanobiotechpharma.com
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The Cause of CAC and it's role in development of Vulnerable Plaque
~Gary S. Mezo

CAC is secondary to an infection by CNPs (CNPs were formerly known as Nanobacteria). CNPs also cause inflammation from their exudate, a LPS Biofilm. CNPs use (oxidize) LDL in their regeneration-cycle. CNPs have 2 pleomorphic modes of growth: fast (replication every 3 days) which involves LPS Biofilm; and slow (replication every 6 days) which involves development of calcium "igloos" around themselves. CNPs, when locked in the intimal-medial space, will be temporarily deprived of their "foodstuff" which is VLDL/LDL from serum/blood. In this mode, CNPs calcify upon themselves, building an intimal-medial "coral-reef" bolus of calcification. As our immune system tries to wall-off the area (like a cyst) , the area is covered with amyloid-like soft plaque. This stabilizes the lesion....but only temporarily. After a while, our immune system recognizes the area as "stable" and does what it normally does to a walled-off area of infection....it tends to regenerate and debulk the area....by initiating the process of neovascularization. In the process of neovascularization----fresh blood containing VLDL & LDL is supplied to the area. Now the CNPs have their required nutrients of lipids. This causes the CNPs to switch to fast replication and form their LPS biofilm....this causes our inflammation and swelling and our immune system is now fighting the infection...this is the "vulnerable plaque" phase. This process waxes and wanes until such time that the calcified plaque burden is so large that it can inflame the area, impair bloodflow and rupture into the lumen. CNPs then bind prothrombin and cause a clotting cascade....this leads to MI. We at NanoBiotech Pharma ( http://www.nanobiotechpharma.com ) have developed NanobacTX to reverse CNP infection & calcification.

Author's disclosure (Jan 18, 2012)
"The Heart" - American Heart Association

Our researchers discovered CNPs and we direct CNP research Worldwide. ( http://www.nanobiotechpharma.com )
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