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Benjamin Werner
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The paper is now published and can be found here:

http://rsif.royalsocietypublishing.org/content/10/85/20130349.full.pdf#page=1&view=FitH

Most imporantly we find some scaling properties of cells carrying any number of mutations in relative general hierarchical tissue structures. One can nicely see, how those hierarchies suppress multiple mutational hits and thus are a natural protection mechanism against cancer. We further can estimate the expected number of distinct mutations at any stage of the hierarchy. Those estimates agree well with recent observations for different blood cancers (in detail discussed for acute lymphoplatic leukemia).
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