Although it may be more meaningful, it is definitely a DIY project that most individuals tend to avoid. That is understandable, though. Nevertheless, there are some communities that build their own caskets. Amish communities build their own caskets, and I have dealt with some Samoan and Native American communities that built their own caskets as well. I have also dealt with others on an individual basis that have built a casket for their deceased loved one.
When asked by others if they can make their own casket (or have someone make it for them), I have always given the same answer: You can make your own casket, just make sure it poses no danger to the human remains that it houses, or to the individuals who will be handling the casket for funeral services and burial, and make sure that the casket you build will fit into the burial vault or crypt. These days, a simple internet search will bring up free DIY building blueprints for caskets and coffins which most laymen could follow without a problem. The casket (or coffin) designs are aesthetically simple, but do the job of housing human remains quite well.
If individuals would like a more elaborate hand-made casket (or coffin), then it would best to approach a woodworker. A woodworker may require more time, though. In fact, a talented woodworker should require more time (at least I think so). If an individual would like an elaborate hand-made casket, and is willing to wait (maybe they don't need it at the moment?), then by all means hit up all the woodworkers in your communities and see who gives you the best price.
The significance of any casket is not measured by who built it, or what materials were used, or what the final price of it was at the end of the day. Whether it is a Batesville Promethean, or a Raised Cloth-Covered Flattop, or a simple hand-made pine box, they all do the same thing. They house human remains. The significance comes from the loved ones left behind. If the family can go home at night content that they have done all they can for the deceased, then they have done their duty. They have paid tribute, shown respect, and express their never-ending love.
When all is said and done, that's all that really matters.