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Jaber Esmaeili
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Rotten egg gas may prevent heart complications in diabetics
Nobody wants rotten eggs, but new research suggests the gas that makes them smell bad could have significant protective effects for people with diabetes.
Researchers at the University of Exeter found hydrogen sulfide — the gas given off by rotten eggs, can treat health complications in the heart, kidneys and eyes of people with diabetes caused by damage to the circulatory system and the heart itself, UPI reported.
Diabetes patients have an excess of glucose in their blood, causing cell mitochondria to leak and produce toxic metabolites of oxygen, which damages blood vessels in the circulation system and heart.
Damage to the circulatory system leads to kidney disease and other complications of diabetes.
In a recent study, published in the journal Pharmacological Research, the researchers tested two drugs, AP39 and AP123, which deliver small quantities of hydrogen sulfide to mitochondria, restoring their efficiency and preventing damage.
“Some people find it amusing that a substance with such a bad reputation can produce these benefits, but nearly every cell in our body makes and responds to tiny amounts of hydrogen sulfide and we have at least three distinct pathways for making this gas in very small quantities so it is very important,” Dr. Matthew Whiteman, a professor at the University of Exeter’s medical school, said.
For the study, researchers tested the two drugs in endothelial cells isolated from blood vessels in the brains of mice, showing the drugs were able to prevent damage caused by malfunctioning mitochondria.
The effects of both substances were long-lasting, the researchers report, suggesting they could be used to treat the heart and circulatory issues faced by diabetes patients.
The next step, Whiteman said that is to continue working toward testing the drugs in humans.
“We’re producing a growing body of evidence that hydrogen sulfide can have a range of health benefits, when carefully administered in minute doses in a highly targeted way in the body,” Whiteman said.
“Mitochondria can even make their own hydrogen sulfide and use it as a ‘fuel’ to keep metabolism efficient. When this ‘fuel’ is lost, mitochondria, cells, blood vessels and tissues are damaged.
“We previously showed that replacing the lost hydrogen sulfide with AP39 reversed this damage in cardiac arrest, hypertension and kidney failure damage and this current study adds AP123 to our portfolio of promising new drugs for diabetes.”


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There's no need to any surplus explanation, itself has a lot more to say…. 
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I am proud of being a follower of such leader and leadership…..
In an exclusive interview, a top Iranian official says that Khomeini personally stopped him from building Iran's WMD program.
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Happy Norouz

Warmest congratulates to my dear friends all who live in the country and abroad and also those who are interested in Iranian ancient culture on the arrival of the new Iranian calendar year, wishing all of you and your honorable family members a happy and prosperous year.

Norouz meaning “new day” marks the Iranian New Year also known as Persian New Year – starting March 21– in the solar hijrah calendar.
Iran is the birthplace of the feast dating back to almost 4,000 years ago.
Although the United Nations General Assembly has officially recognized Norouz as an Iranian festival, the annual ceremony is not limited to Iran.
In addition to Iran, over 300 million people in Turkey, Uzbekistan, Azerbaijan, India, Pakistan, Afghanistan, Tajikistan, Kazakhstan, Kyrgyzstan and other parts of the world celebrate the auspicious occasion.
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    AFTER YEARS OF TELLING PEOPLE CHEMOTHERAPY IS THE ONLY WAY TO TRY AND ELIMINATE CANCER, JOHNS HOPKINS IS FINALLY STARTING TO TELL YOU THERE IS AN ALTERNATIVE WAY … 1. Every person has...
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Compare civilizations

Civilization is not solely about having high-tech technologies and or huge constructions, rather it should appear on our behaviors, our manners towards each other….

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news , world , middle east , Iran , photo , video , Asia ,
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A Humorous Story

Speaking without thinking can treble your troubles as this ancient story demonstrates.

A man was caught stealing a bag of onions and taken before a judge.

The judge gave him a choice of three punishments:

1. Eat the onions he had stolen at one sitting

2. Submit to a hundred lashes of the whip

3. Pay a fine

the man said he would eat the onions. He began confidently enough but after eating a few, his eyes began to burn, his nose started running and his mouth felt as if it were on fire.

“I can’t eat the onions,” he said. “Give me the lashes instead.”

But after he had received a few strokes he began to turn and twist to avoid the whip.

“I can’t bear it!” he screamed, finally. “I’ll pay the fine.”

So he paid the fine and was let off, but he became the laughing-stock of the city for having taken three punishments for the same crime.
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Great wall of Gorgan older than Chinese wall.
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