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Quantitative Proteomics
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A Collaborative Laboratory at Columbia University
A Collaborative Laboratory at Columbia University

33 followers
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Quantitative Proteomics's posts

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The installation of the Orbitrap Q Exactive HF is in progress!
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New Book Chapter:
Brown LM. Quantitative Shotgun Proteomics with Data-Independent Acquisition and Traveling Wave Ion Mobility Spectrometry: A Versatile Tool in the Life Sciences
Adv Exp Med Biol. 2014;806:79-91. doi: 10.1007/978-3-319-06068-2_4.

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Ergel B, Gill ML, Brown L, Yu B, Palmer AG 3rd, Hunt JF.
Protein dynamics control the progression and efficiency of the catalytic reaction cycle of the Escherichia coli DNA-repair enzyme AlkB. J Biol Chem. 2014 Oct 24;289(43):29584-601

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This PLOS blog highlighted our proteomics study as an excellent example of personalized medicine

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Jin Yang, Yao Li, Lawrence Chan, Yi-Ting Tsai,Wen-Hsuan Wu,
Huy V. Nguyen, Chun-Wei Hsu, Xiaorong Li, Lewis M. Brown, Dieter Egli,
Janet R. Sparrow and Stephen H. Tsang. Validation of genome-wide association study (GWAS)-identified disease risk alleles with
patient-specific stem cell lines. Human Molecular Genetics, 2014 Advance Access published February 18, 2014

This series of posts today are references to some of our recent publications

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Yang, Wan S., SriRamaratnam, R., Welsch, Matthew E., Shimada, K., Skouta, R., Viswanathan, Vasanthi S., Cheah, Jaime H., Clemons, Paul A., Shamji, Alykhan F., Clish, Clary B., Brown, Lewis M., Girotti, Albert W., Cornish, Virginia W., Schreiber, Stuart L., and Stockwell, Brent R. 2014. Regulation of Ferroptotic Cancer Cell Death by GPX4. Cell 156(1-2): 317-331.

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Alegre-Aguaron, E., Sampat, S.R., Xiong, J.C., Colligan, R.M., Bulinski, J.C., Cook, J.L., Ateshian, G.A., Brown, L.M., and Hung, C.T. 2014. Growth Factor Priming Differentially Modulates Components of the Extracellular Matrix Proteome in Chondrocytes and Synovium-Derived Stem Cells. PLoS ONE 9(2): e88053.
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