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Paolo Pascucci
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Gut Bacteria Drives Autoimmune Diseases

Bacteria found in the small intestines of mice and humans can travel to other organs and trigger an autoimmune response, according to a new Yale study. The researchers also found that the autoimmune reaction can be suppressed with an antibiotic or vaccine designed to target the bacteria, they said.

The research is in Science. (full access paywall)
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Study first to demonstrate brain mechanisms that give The Iceman unusual resistance to cold

Dutch adventurer Wim Hof is known as "The Iceman" for good reason. Hof established several world records for prolonged resistance to cold exposure, an ability he attributes to a self-developed set of techniques of breathing and meditation—known as the Wim Hof Method—that have been covered by the BBC, CNN, National Geographic and other global media outlets. Yet, how his brain responds during cold exposure and what brain mechanisms may endow him with this resistance have not been studied—until now. Wayne State University School of Medicine professors Otto Muzik, Ph.D., and Vaibhav Diwadkar, Ph.D., changed that. Their publication, "Brain Over Body: A study on the willful regulation of autonomic function during cold exposure," published in the journal NeuroImage, is the first to study how The Iceman's brain responds during experimentally controlled whole-body cold exposure. These investigations are part of the scientists' series of seminal studies launched in 2014 on how the human brain responds to thermoregulatory challenges. The results document compelling brain processes in The Iceman and present intriguing possibilities for how his techniques might exert positive effects related to disorders of the immune system and even psychiatry.
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Our memory comes from an ancient virus, neuroscientists say

The particulars surrounding how our memory works has baffled neuroscientists for decades. Turns out, it’s a very sophisticated process involving several brain systems. What about on the molecular level? Inside the brain, proteins don’t stick around longer than a few minutes. And yet, our memories can hang on for our entire lifetime. Recently, an international collaboration of researchers from the University of Utah, the University of Copenhagen, and the MRC Laboratory of Molecular Biology in the UK, discovered something strange about a protein called Arc. This is essential to long-term memory formation. What they found was that it has very similar properties to how a virus infects its host. Their findings were published in the journal Cell. In it researchers write, “The neuronal gene Arc is essential for long-lasting information storage in the mammalian brain, mediates various forms of synaptic plasticity, and has been implicated in neurodevelopmental disorders.” They go on to say, “little is known about Arc’s molecular function and evolutionary origins.” As a result of the study, researchers now believe that a chance encounter occurring hundreds of millions of years ago, led to Arc’s centrality in our memory function today. Assistant professor of neurobiology Jason Shepherd, Ph.D. of the University of Utah, led this research project. He’s dedicated himself to the study of the protein for the last 15 years.

link: http://bigthink.com/philip-perry/our-memory-comes-from-an-ancient-virus-neuroscientists-say
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Un nuovo studio italiano confronta per la prima volta i profili di costo-efficacia di quattro diversi vaccini antinfluenzali indicati per la popolazione italiana di età pari o superiore ai 65 anni.
Tutti i vaccini disponibili sono risultati convenienti rispetto alla non vaccinazione. Dal punto di vista economico, quelli adiuvati e largamente impiegati in Italia hanno mostrato il profilo più favorevole.

Capri S, Barbieri M, de Waure C, Boccalini S, Panatto D. Cost-effectiveness analysis of different seasonal influenza vaccines in the elderly Italian population. Hum Vaccin Immunother. 2018 Feb 9:1-11.
https://doi.org/10.1080/21645515.2018.1438792
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Dal Guggenheim Museum di New York più di 200 libri di arte da scaricare gratuitamente.

ll Guggenheim Museum di New York ha messo a disposizione 50 anni di cataloghi d’arte, liberamente consultabili e scaricabili. Tutti i libri possono essere visualizzati online o scaricati gratuitamente nei formati Pdf e EPub cliccando semplicemente su questo link: https://archive.org/details/guggenheimmuseum

L’intera collezione di cataloghi e libri d’arte è in inglese, ma ci sono anche testi in italiano quali: "Omaggio a Lucio Fontana”, "Guggenheim, Venezia-New York sessanta opere, 1900-1950“, "Capolavori del Guggenheim: il grande collezionismo da Renoir a Warhol” ecc. , o diversamente i cataloghi in inglese come ad esempio “The italian metamorphosis, 1943-1968" https://archive.org/details/metph00cela, in una bella ricostruzione della storia dell'arte italiana.
L'intera proposta è davvero ampia. Buona ricerca.

Lucio Fontana, olio - Catalogo Fondazione Fontana O 1, Milano
#ArtLover #Art #Guggenheim #Arte #StoriaDellArte
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