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In November 2011, two campus police officers pepper-sprayed protesters at University of California, Davis. If you’d like to learn about the chain of incompetence that led to this, read the in…
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21 Anti-histamine Foods That Fight Inflammation And Stabilise Mast-Cells
#healthyliving #Fight #Inflammation  anti-histamine #foods  
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If you have histamine intolerance, mast-cell activation disorder, or any other inflammatory disorder, then here are 21 anti-histamine foods that fight inflammation and stabilise mast-cells naturally (and also a further 21 supplements to boost nutritional reserves):

anti histamine watercress

1. Watercress (Nasturtium officinale)
Watercress is a cruciferous vegetable that has a peppery, tangy, taste like rocket. It is considered one of the most nutrient dense plants commonly available. A study showed that watercress inhibits 60% of all histamines released from mast cells.

Study: Goda, Hoshino K, Akiyama H, Ishikawa T, Abe Y, Nakamura T, Otsuka H, Takeda Y, Tanimura A, Toyoda M, “Constituents in watercress: inhibitors of histamine release from RBL-2H3 cells induced by antigen stimulation”, Biol Pharm Bull. 1999 Dec;22(12):1319-26.

anti histamine pea sprout

2. Pea Sprouts (Pisum Sativum)
Pea sprouts contain a high concentration of diamines oxidase (the enzyme that degrades extra-cellular histamine) during the cotyledon phase. All the fabaceae family contain DAO, but it is particular high in, pea (pisum sativum), lentil (lens culinaris), and chickpea (cicer arietinum) seedlings.

Study: Masini, Emanuela, et al. “Pea seedling histaminase as a novel therapeutic approach to anaphylactic and inflammatory disorders.” The Scientific World Journal 7 (2007): 888-902.

anti histamine onions

3. Onions (Allium Cepa)
The humble onion (including the spring onion) is incredibly nutritious and an important prebiotic. Onions have been shown to inhibit histamine release, stabilise mast cells, and even lower histamine levels extra-cellularly in blood plasma.

Study: P. Kaiser, M.S. Youssouf, S.A. Tasduq, S. Singh, S.C. Sharma, G.D. Singh, V.K. Gupta, B.D. Gupta, and R.K. Johri, Anti-Allergic Effects of Herbal Product from Allium Cepa (Bulb), Journal of Medicinal Food. April 2009, 12(2): 374-382.

anti histamine garlic

4. Garlic (Allium Sativum)
Like onions, garlic, is incredibly nutritious, high in anti-oxidants, and a prebiotic. Garlic has also been shown to inhibit histamine release from mast cells.

Study: Hogberg, Bertil. “Inhibitory action of allicin on degranulation of mast cells produced by compound 48/80, histamine liberator from ascaris, lecithinase A, and antigen.” Acta Physiologica Scandinavica 44.2 (1958): 157-162.

anti histamine moringa

5. Moringa (Moringa Oleifera)
Moringa is a “super-food” that has found its way onto health food shelves. It is so nutrient dense that it has historically been used to treat malnutrition. A study has shown that Moringa inhibits 72% of all histamines released, making it almost as effective as Ketitofen.

Study: Mehta, Anita, and Babita Agrawal. “Investigation into the mechanism of action of Moringa oleifera for its anti-asthmatic activity.” Oriental Pharmacy and Experimental Medicine 8.1 (2008): 24-31.

anti histamine holy basil

6. Holy Basil (Ocimum Tenuiflorum)
Holy basil is a herb in the basil family. It has a subtle flavour that is minty, and mildly floral, with a natural sweetness. It is an adaptogen with anti anaphylactic, anti histamine, and mast cell stabilising properties. Whilst dried teas are readily available there is really nothing like the taste of fresh herbs which are easy to grow.

Study: G Sridevi, P Gopkumar, S Ashok, C Shastry. Pharmacological Basis For Antianaphylactic, Antihistaminic And Mast Cell Stabilization Activity Of Ocimum Sanctum. The Internet Journal of Pharmacology. 2008 Volume 7 Number 1.

anti histamine thyme

7. Thyme (Thymus Vulgaris)
Thyme is a nutrient dense herb. It has exceptionally high levels of Vitamin C, combined with flavonoids, that stabilises mast cells. It also has anti microbial benefits.

Study: Watanabe, Jun, Hiroshi Shinmoto, and Tojiro Tsushida. “Coumarin and flavone derivatives from estragon and thyme as inhibitors of chemical mediator release from RBL-2H3 cells.” Bioscience, biotechnology, and biochemistry 69.1 (2005): 1-6.

anti histamine tarragon

8. Tarragon (Artemesia Dracunculus)
Tarragon has a pleasant anise flavour. It is one of the highest anti-oxidant food sources amongst herbs. A study shows that it stabilises mast cells.

Study: Watanabe, Jun, Hiroshi Shinmoto, and Tojiro Tsushida. “Coumarin and flavone derivatives from estragon and thyme as inhibitors of chemical mediator release from RBL-2H3 cells.” Bioscience, biotechnology, and biochemistry 69.1 (2005): 1-6.

anti histamine chamomile

9. Chamomile (Matricaria Recutita)
Chamomile is typically consumed as a tea. Fresh flowers are frequently available and are preferable to dried. A study found that chamomile acted in a dose-dependent manner to inhibit histamine release from mast cells.

Study: Chandrashekhar, V. M., et al. “Anti-allergic activity of German chamomile (Matricaria recutita L.) in mast cell mediated allergy model.” Journal of ethnopharmacology 137.1 (2011): 336-340.

anti histamine nettle

10. Nettle (Urtica Dioica)
Nettle is typically consumed as a tea. It has been shown to be a potent anti histamine (working at the H1 receptor), and mast cell stabiliser.

Study: Roschek, Bill, et al. “Nettle extract (Urtica dioica) affects key receptors and enzymes associated with allergic rhinitis.” Phytotherapy research 23.7 (2009): 920-926.

anti histamine peppermint

11. Peppermint (Mentha ×Piperita)
The flavonoids in peppermint have been found to have a potent inhibitory effect on histamine from mast cells. It was particularly effective for allergic rhinitis, and has traditionally been used as an H2 antagonist.

Study: Inoue, Toshio, et al. “Antiallergic effect of flavonoid glycosides obtained from Mentha piperita L.” Biological and Pharmaceutical Bulletin 25.2 (2002): 256-259.

anti histamine nigella sativa

12. Nigella Sativa (Black Cumin) Seed and Oil
Nigella Satvia is also called fennel flower, black cumin, roman coriander, and onion seeds. It has a slightly bitter herbal flavour similar to oregano. It acts an anti histamine, and anti oxidant, protecting the gastric mucosal layer. It can be consumed either as a seed or as the oil.

Study: M Kanter, O Coskun, H Uysal, The antioxidative and antihistaminic effect of Nigella Sativa and its major constituent, thymoquinone on ethanol-induced gastric mucosal damage, Archives of toxicology, 2006 – Springer.

anti histamine galangal

13. Galangal (Alpinia Galanga)
Galangal is also called “Thai Ginger” and is readily available at Asian grocers. It has a subtle delicate flavour that has a gingery, lemongrass, lightly floral flavour. A study shows that it is extremely effective at stabilising mast cells and preventing anaphylaxis.

Study: Hisashi Matsuda, Toshio Morikawa, Hiromi Managi, Masayuki Yoshikawa, Antiallergic principles from Alpinia galanga: structural requirements of phenylpropanoids for inhibition of degranulation and release of TNF-alpha and IL-4 in RBL-2H3 cells, Bioorganic & Medicinal Chemistry Letters Volume 13, Issue 19, 16 October 2003, Pages 3197–3202.

anti histamine ginger


14. Ginger (Zingiber Officinale)
Ginger is a rhizome that inhibits allergic reactions. It has traditionally been used as an H2 inhibitor but a 2009 study shows that it also acts as a mast cell stabiliser.

Study: Chen, Bing-Hung, et al. “Antiallergic potential on RBL-2H3 cells of some phenolic constituents of Zingiber Officinale (Ginger).” Journal of natural products72.5 (2009): 950-953.

anti hsitamine lotus root

15. Lotus Root (Nelumbo Nucifera) 
Lotus roots are available from most Asian supermarkets. They have an immune-modulating effect with mast cell stabilising properties and a study found they inhibit the release of histamines by up to 70%.

Study: Mukherjee, Debajyoti, et al. “Exploring the potential of Nelumbo nucifera rhizome on membrane stabilization, mast cell protection, nitric oxide synthesis, and expression of costimulatory molecules.” Immunopharmacology and immunotoxicology 32.3 (2010): 466-472.

anti histamine turmeric

16. Turmeric (Curcuma Longa)
Turmeric is the spice that gives curry its colour, and on its own it has a savoury, almost cheddar like taste.  The fresh rhizomes are increasingly available and can be frozen and grated over most savoury dishes as a condiment. Turmeric has powerful anti-inflammatory and anti-oxidant properties. A study found that it inhibited mast cell activation.

Study: Lee, Jun Ho, et al. “Curcumin, a constituent of curry, suppresses IgE-mediated allergic response and mast cell activation at the level of Syk.” Journal of Allergy and Clinical Immunology 121.5 (2008): 1225-1231.

anti histamine pomegranate

17. Pomegranate (Punica Granatum)
Pomegranates have a sweet but tart taste and are used in both savoury and sweet foods. They contain polyphenols, such as tannins and anthocyanins, and are higher in anti oxidants than green tea. A study showed that they act as mast cell stabilisers.

Study: Rasheed, Zafar, et al. “Polyphenol-rich pomegranate fruit extract (POMx) suppresses PMACI-induced expression of pro-inflammatory cytokines by inhibiting the activation of MAP Kinases and NF-B in human KU812 cells.” J Inflamm (Lond) 6 (2009): 1.

anti histamine apple

18. Apples (Malus Domestica)
The nutrients of apples are concentrated in the skin. Apples are not so much rich in one nutrient but have a wide range of flavonoids and polyphenols. A study has shown that they inhibit the release of histamines from mast cells.

Study: Kanda, Tomomasa, et al. “Inhibitory effects of apple polyphenol on induced histamine release from RBL-2H3 cells and rat mast cells.” Bioscience, biotechnology, and biochemistry 62.7 (1998): 1284-1289.

anti histamine capers

19. Capers (Capparis Spinosa)
Capers add a tangy peppery taste to dishes. They are one of the richest sources of quercetin. Capers have antimicrobial, anti oxidative, anti inflammatory, and antiviral properties. A study also found them to be anti-histaminic. The study was performed with fresh capers (not preserved in vinegar but preserved in salt*).

Study: Trombetta, Domenico, et al. “Antiallergic and antihistaminic effect of two extracts of Capparis spinosa L. flowering buds.” PTR. Phytotherapy research19.1 (2005): 29-33.

* I have received a number of questions about the preservation in salt. There is strong scientific evidence that preservation in salt prevents histamine formation.

Study: Chong, C. Y., Abu Bakar, F., Russly, A. R., Jamilah, B. and
Mahyudin, N. A., MiniReview; The effects of food processing on biogenic amines formation, International Food Research Journal 18(3): 867-876 (2011).

anti histamine mangosteens

20. Mangosteens (Garcinia Mangostana)
Mangosteens are a tropical fruit the size of small apples. Their flesh consists of creamy white segments with a delicate, sweet taste, and melt in the mouth texture. They are increasingly available in supermarkets. Studies not only show that they lower the c-reactive protein inflammation marker and, act as an anti-histamine (H1), but that they also inhibit mast cell degranulation.

Study: Itoh, Tomohiro, et al. “Inhibitory effect of xanthones isolated from the pericarp of garcinia mangostana L. on rat basophilic leukemia RBL-2H3 cell degranulation.” Bioorganic & medicinal chemistry 16.8 (2008): 4500-4508.

Chairungsrilerd N, Furukawa K, Ohta T, et al. Histaminergic and serotonergic receptor blocking substances from the medicinal plant Garcinia mangostana. Planta Med 1996;62:471-2

anti histamine peach

21. Peaches (Prunus Persica)
Peaches are a summer fruit, that are sweet and juicy. A study found that they inhibited mast cell derived allergic inflammation.

Study: Shin, Tae-Yong, et al. “Anti-allergic inflammatory activity of the fruit of Prunus Persica: Role of calcium and NF-?B.” Food and Chemical Toxicology 48.10 (2010): 2797-2802.


22. Black Rice Bran
Black rice is believed to have many notable health benefits. Researchers have found that a 10% diet of black rice reduced inflammation and inhibited the release of histamine from mast-cells by about 32%. Brown rice did not have the same benefits.

Study: Sun Phil Choi, Sung Phil Kim, Mi Young Kang, Seok Hyun Nam, Mendel Friedman. Protective Effects of Black Rice Bran against Chemically-Induced Inflammation of Mouse Skin. Journal of Agricultural and Food Chemistry, 2010; 58 (18): 10007 DOI: 10.1021/jf102224b

23. Mung Bean Sprouts
A recent laboratory study found mung bean sprouts (after 48 h of growth) to provide significant protection against mast cell degranulation and histamine release due to their high flavanoid content.

Study: Li, Li, et al. “Anti-allergic effects and related active constituents of mung bean (Vignaradiatus Linn) sprouts.” Food Science and Biotechnology 25.2 (2016): 553-559.

Advanced Supplements
These 21 (now 23) foods have clinical trials in support of anecdotal evidence. Some are even proven to be as effective as commonly used mast cell stabilising medication.

I still believe that whole foods provide many if not all of the natural anti-histamines and mast-cell stabilising nutrients our bodies need. However, in researching this article, I also identified 21 advanced supplements, that can build nutritional reserves, and provide natural anti-histamine and mast-cell stabilising support.

You can grab your personal copy of these 21 advanced supplements, together with a summary of these 21 foods, by clicking the image below.
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universe shifts back into alignment Bernie Sanders Takes National Lead
A new Reuters/Ipsos poll released Thursday shows Bernie Sanders beating Hillary Clinton by one point with registered Democratic voters. The survey of 1,680 registered voters, 635 of whom identified as Democrats, was conducted between…
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