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Stephen Hsu
Physicist, Startup Founder, Blogger, Dad
Physicist, Startup Founder, Blogger, Dad
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Stephen Hsu's posts

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Pleiotropy, balancing selection, and all that: heart disease
This paper suggests that some genetic variants which increase risk of coronary artery disease have been maintained in the population because of their positive effects in other areas of fitness, such as reproduction. Genetic loci associated with coronary art...

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Don't Touch the Computer
Under what circumstances should humans intervene to override algorithms? From what I have read I doubt that a hybrid team of human + AlphGo would perform much better than AlphaGo itself. Perhaps worse, depending on the epistemic sophistication and self-awar...

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Genetic variation in Han Chinese population
Largest component of genetic variation is a N-S cline (phenotypic N-S gradient discussed here ). Note variance accounted for by second (E-W) PC vector is much smaller. The Han population is fairly homogeneous in genetic terms. Neandertal ancestry does not v...

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The Loveless (1982) and Born to Run
The Loveless (free now on Amazon Prime ) was the first film directed by Kathryn Bigelow (Point Break, Zero Dark Thirty) and also to first first film role for a young Willem Dafoe. Dafoe has more leading man star power in this role than in most of his subseq...

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Superhuman Relational Reasoning (DeepMind)
These neural nets reached super-human (better than an average human) performance on tasks requiring relational reasoning. See the short video for examples. A simple neural network module for relational reasoning https://arxiv.org/abs/1706.01427 Adam Santoro...

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Probing deep networks: inside the black box
See also AI knows best: AlphaGo "like a God" : Humans are going to have to learn to "trust the AI" without understanding why it is right. I often make an analogous point to my kids -- "At your age, if you and Dad disagree, chances are that Dad is right" :-)...

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Yoel Romero, freak athlete
Romero is 40 years old! He is a former World Champion and Olympic silver medalist for Cuba in freestyle wrestling. He lost a close championship fight yesterday in the UFC at 185lbs. The guy he lost to, Robert Whittaker, is a young talent and a class act. It...

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Politico: Trump could have won as a Democrat
I'm old enough to have been aware of Donald Trump since before the publication of Art of the Deal in 1987. In these decades, during which he was one of the best known celebrities in America, he was largely regarded as a progressive New Yorker, someone who c...

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10 Years of GWAS Discovery
See post from 2012: Five years of GWAS discovery to see how far the field of human genomics has advanced in just a short time. 10 Years of GWAS Discovery: Biology, Function, and Translation The American Journal of Human Genetics 101, 5–22, July 6, 2017 DOI:...

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Building the Gadget: A Technical History of the Atomic Bomb
This is the best technical summary of the Los Alamos component of the Manhattan Project that I know of. It includes, for example, detail about the hydrodynamical issues that had to be overcome for successful implosion. This work drew heavily on von Neumann'...
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