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Todd Nickle
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Professor of Biology, Mount Royal University
Professor of Biology, Mount Royal University

43 followers
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Elucidating Codons with Random Copolymers
Before we got a codon table as we know it today, scientists had to figure out what the letters were in each of the 64 combinations of triplets of nucleotides.  It is child's play to get all the possible codons, but what they mean  is another story! The leve...
Elucidating Codons with Random Copolymers
Elucidating Codons with Random Copolymers
universitygenetics-geneexpression.blogspot.com
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Werecreatures! Scaaaary!
I took some questions designed by Dr. Gillian Davis and fleshed them out a bit.  Here they are. For each Define appropriate gene and
allele symbols according to Advanced Nomenclature rules.   Fill in the table. The
genotypes must reflect the correct gene or...
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Calculating Interference two ways
I've demonstrated above that I calculate interference by comparing the ratios of DCO offspring (observed/expected).  It's simply a ratio to show what percentage of DCOs you see in the offspring compared to what you're expecting. The McGraw-Hill Hartwell et ...
Calculating Interference two ways
Calculating Interference two ways
universitygenetics-mapping.blogspot.com
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More practice!
Another example - Can you spot what's tricky about these data? You cross a
triple-mutant female fly from its stock vial with a wild-type stock male.   The F 1 females are testcross and the
following data are obtained: reduced bristle, black
body 1132 redu...
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Draw and number a pentose
Here's an important skill:  you should be able to draw and number a pentose sugar.  The bases are a bit harder to draw - they have all kinds of functional groups and there are two fairly different structures (purines and pyrimidines). You should for sure re...
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Operons!
Hi everyone. Here's a worksheet to practice your skills with gene regulation in prokaryotes using the lac operon. You can download the worksheet as a Word document online . Here are the solutions!  You can make them larger by going right to YouTube (click i...
Operons!
Operons!
universitygenetics-geneexpression.blogspot.ca
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The "Find the Intron" Game!
Here's a chance for you to try your hand at gene expression.  In this exercise, you're given a piece of DNA and you're told that it encodes an mRNA that has a single intron.  You need to transcribe and translate it, and you also need to use protein informat...
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Operon example from Sanders book
Prokaryotes often cluster the information for proteins involved in the same biochemical pathway all together.  Each protein is encoded by what we call and "ORF" each of which has its own start and stop codon.  The old term for an ORF was a "cistron", and fo...
Operon example from Sanders book
Operon example from Sanders book
universitygenetics-geneexpression.blogspot.ca
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A Fusion Operon Question
What's a fusion operon?  Ask Dr. David Bird, an evil scientist who likes to test the understanding of his students regarding gene regulation by creating unholy and absurd mixtures of operons.  Well, that's overstating it, but it's a neat puzzle that is crea...
A Fusion Operon Question
A Fusion Operon Question
universitygenetics-geneexpression.blogspot.ca
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How cool is that structure?
Today in class we were to go over the structure of DNA.  The structure is intimately linked to its function, so the base-pairing aspect is HUGE.  The fact that a string of bases on one DNA molecule can dictate the order of nucleotides on the partner molecul...
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