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NeuroRx Pharma
NeuroRx, Inc. is a clinical stage, small pharmaceutical company developing novel therapeutics for treatment of ASIB in Bipolar Depression
NeuroRx, Inc. is a clinical stage, small pharmaceutical company developing novel therapeutics for treatment of ASIB in Bipolar Depression

NeuroRx Pharma's posts

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#back2basics_bipolar w this great intro video to bipolar disorder and the different ways people live with the condition. Thanks to Helen M Farrell, MD &
+TED-Ed for a beautiful video. 11%-20% of individuals with bipolar disorder succumb to suicide. +NeuroRx Pharma is committed to the field of #ASIB in #bipolar #depression. #endstigma

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We often get asked about the difference between #bipolar 1 and 2. Thanks to
+Julie A. Fast and for taking us #back2basics_bipolar. Bipolar Disorder has a very high risk of suicide. +NeuroRx Pharma committed to the field of #ASIB in #bipolar #depression. #endstigma, follow our journey

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In pharma their is little attention to Bipolar Disorder, yet the unmet needs are very high. An important read on the challenges of diagnosing #bipolar. According to this study, 69% of patients are initially misdiagnosed. Possibly more than 1/3 remain misdiagnosed for more than 10 years! @NeuroRx is focused on #ASIB in Bipolar #Depression.

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Learn about the first treatment for Acute #Suicidal Ideation/Behavior (#ASIB) in Bipolar Depression.
+NeuroRx Pharma CEO, Jonathan C. Javitt, M.D., M.P.H. speaks with Tori Rodriguez on the progress of #NRX101, and our fight to bring the first approved treatment for ASIB to market. Special thanks to Tori Rodriguez, MA, LPC and +Psychiatry Advisor for publishing this

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Today is #WordBipolarDay. We thank the inspirational individuals and advocacy/support groups who work tirelessly to help their community. Special nod to +International Bipolar Foundation and ISBD for for sponsoring. Let's use this day as a reminder to #breakthestigma and share the messages of hope. NeuroRx joins this quest - we are working to develop a treatment for Acute #Suicidal Ideation/Behavior in (#ASIB) in #Bipolar Depression. Learn more and participate here:

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We're proud to sponsor the Israel Brain Technologies #Braintech Conf. - Mar 6-7 in TLV.
Come join our symposium TODAY - "In Search of a Cure"
Dr. J John Mann will present a keynote address at 9AM. At 10AM, NeuroRx Pharma CEO, Jonathan Javitt to host the panel: "In Search of a cure - A Druggable Target for #Suicide"
Dr. Mann will be joining the panel, along with Dr. Eyal Fruchter, Dr. Daniel Javitt, and Dr. Joshua Kantrowitz
Find out more here: 

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This article by Nina Notman in Chemistry World a compelling review of the #NMDA treatments in development for #depression and #suicide: #NRX101 is the only drug focused on #ASIB in #Bipolar Depression, where suicidal risk is highest. Different opinions around mechanism - future clinical data ultimate differentiator. Other elements of emerging treatments appear to be:

a) Route of administration (oral vs. IV vs. intranasal),
b) Requirements for in-clinic vs. outpatient administration, including potential risk of abuse, and dissociative effects
c) Requirements for adjunctive anti-depressant treatment.

Of note, others are also now interested in suicidal ideation, which in our recent survey among those who follow the field of Neuroscience rated as #3 most poised for breakthrough (see our website:

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NeuroRx has received FDA clearance to proceed with its Phase 2b/3 study protocol under an Investigational New Drug (IND) application and is now enrolling study sites for its clinical trial of NRX-101. NRX-101 is the first oral drug to target Acute Suicidal Ideation & Behavior (ASIB) in bipolar depression. The clinical trial seeks to demonstrate that NRX-101 is safe and effective in maintaining remission from ASIB and depression following initial stabilization with ketamine. Click for more info:

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There are more than 100 suicides each day in the United States. Yet, there is no approved therapeutic for the treatment of Acute/Elevated Suicidal Ideation in Bipolar Depression (ASIBD/ESIBD). See what NeuroRx is doing to help on our website.
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