http://v4.jasonsantamaria.com/articles/a-real-web-design-application/

"So why not build a desktop app for web design around WebKit? I’m not talking about an in-browser AJAX toolkit for dragging elements around and changing fonts, but an actual desktop application built with WebKit as the core to its display. It could have accurate rendering and previews for the way page elements would look, but with some of the WYSIWYG tools desktop design apps have. We wouldn’t just approximate pixels in a flat comp, our CSS would be baked in to the layouts we draw and create on the page. And as Webkit grows, so too could this new app, always taking advantage of the latest and greatest functionality. Just like a browser, it could pull assets from remote servers; and just like a desktop app, it could make use of local processing power and OS-level functionality. This would allow it to effectively combine some of the best of both worlds, with a foot firmly planted in the web.

The advantages would be monumental, allowing a strong creative and explorative process, while seeing how things could react on a live stage. It would fulfill many of the items on my wishlist because these are already part of core browser functionality. We would essentially be designing with live page elements; not a picture of a text field—but a text field you could click into and start typing, and then drag to a different area of the page entirely."
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