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Ivan Mashchenko
Attends School of Hard Knocks
Lives in Prague, Czech Republic
16,232 followers|4,406,461 views
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Ivan Mashchenko

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The Beauty of Silence

© Mark Ruti Photography
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Alcohol, Tobacco and Time Spent Outdoors Linked to Brain Connections

Data from the world's largest brain and body scanning study has been released.

The research is in Nature Neuroscience. (full access paywall)
Summary: Researchers have released data from the world's largest brain and body scanning study.Source: Imperial College London.Data from the world's largest brain and body scanning study has
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First real-time look at genes switching off in live human brains

The switching-off of genes in the human brain has been watched live for the first time. By comparing this activity in different people’s brains, researchers are now on the hunt for abnormalities underlying disorders such as Alzheimer’s disease and schizophrenia. To see where genes are most and least active in the brain, Jacob Hooker at Harvard Medical School and his team developed a radioactive tracer chemical that binds to a type of enzyme called an HDAC. This enzyme deactivates genes inside our cells, stopping them from making the proteins they code for.

When injected into people, brain scans can detect where this tracer has bound to an enzyme, and thus where the enzyme is switching off genes. The switching-off of genes by HDACs is a form of epigenetics – physical changes to the structure of DNA that modify how active genes are without altering their code. Until now, the only way to examine such activity in the brain has been by looking at post-mortem brain tissue. In the image above from the study, genes are least active in the red regions, such as the bulb-shaped cerebellum area towards the bottom right. The black and blue areas show the highest levels of gene activity – where barely any HDACs are present – and the yellow and green areas fall in between.
A radioactive tracer has let researchers watch patterns of gene activity across healthy brains, as well as in those of people with schizophrenia
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“Learning from this model, we can understand what’s really going on in these superconductors, and what one should do to make higher-temperature superconductors, approaching hopefully room temperature.” -Professor Martin Zwierlein, +Massachusetts Institute of Technology (MIT)

The research was supported in part by the +National Science Foundation, AFOSR PO: Dr. Tatjana Curcic, Atomic and Molecular Physics, ARO, and the David and Lucile Packard Foundation. #physics   #superconductivity   #basicresearch
Observations of atomic interactions could help pave way to room-temperature superconductors.
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A new study from MIT reveals that a brain region dedicated to reading has connections for that skill even before children learn to read.

#neuroscience #reading #brain #MIT
Pathways that exist before kids learn to read may determine development of brain’s word recognition area.
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Work
Occupation
A twisted mentat
Skills
IT consultant and project manager, Scala & C# & T-SQL developer, SMB IT system engineer, hotel and travel agency manager, business negotiatior, UX and business process critic, QA enthusiast, certified Rockwell Arena simulation modelling speciallist and trainer, fluent English, Russian and Czech speaker
Employment
  • IT consultant and project manager, present
Places
Map of the places this user has livedMap of the places this user has livedMap of the places this user has lived
Currently
Prague, Czech Republic
Previously
Saint-Petersburg, Russian Federation - Yekaterinburg, Russian Federation - Vyborg, Russian Federation - Říčany, Czech Republic - Siegen, Germany - Stockholm, Sweden
Links
Other profiles
Story
Tagline
Jedem das seine
Introduction
In general

I am a person of very wide tastes and interests. I enjoy everything that «has a heart» (© C. Castañeda). I enjoy to meet and try to understand different people, to study and master different new things, to explore, to feel, to taste, to understand.

Having some areas of professional expertise secured and going further I consider myself a generalist rather than a specialist. The ultimate goal of a generalist is being a polymath and reconstructing the whole puzzle, the ultimate goal for a specialist as he specializes is, saying roughly, knowing everything about nothing. «... specialization is for insects.» " (© Lazarus Long (R. A. Heinlein)) :-)

In practice


I mostly earn my bread from working in the IT industry and its crossings with finance, media and travel industries.

My favourite programming languages are Scala and C# but I can use many other languages if they fit better (for a particular task). I use Linux (XUbuntu) as my primary OS (I also like Windows XP, FreeBSD, QNX and DOS). I am a certified Rockwell Arena simulation engineer and trainer.

Location and communication

I live in Prague, Czech Republic (and feel it being the best place in the world I have been to, according to my taste).

I can speak English, Russian and Czech languages fluently. I can understand Slovak, Ukrainian and Belorussian with almost the same ease. I've also got some basic skills in French (used to speak near fluently but have forgotten because of lack of practice), German (studying right now) and Polish. Needless to say I am fond of languages.

I prefer e-mail as the main communication channel, Skype when an audial conversation feels more convenient and Google+ as a social network. I am glad to meet exciting people from all over the world.

Social networking policy

All my posts are either public (the majority) or personal. I make no limited or circle-specific and almost no community posts.

I can hardly be insulted religiously (though I am not a pure atheist and don't advocate abuse) or any way alike. I never report posts other than those I can qualify as SPAM. At the same time I can myself post or reshare something of questionable appropriateness on occasion - if you are going to dislike that and don't want to see anything like that in your stream (or, for example, if your underage children can access your Googe+ on occasion) I strongly encourage you to unfollow and, if necessary, block me rather than to report.

I rarely post any original content. I mostly reshare whatever catches my eye. But I am not a bot and am prone to very active discussion participation in comments.

I use to review people who starts following me (as far as Google+ notifies me about it) and follow back if the profile seems an alive, interesting personality (I also don't mind explicit content or content of questionable appropriateness). But don't bother following me if you're a bot or a network marketer doing it just to get me follow back. If you think I might like following you but believe I have missed your emergence - please don't hesitate to leave a comment at a post of mine or contact me personally.

If you can't see any activity from my side for a relatively long period of time - that most probably neither means I'm dead nor I have given up using Google+. Some times I just need some solitude.

Religious views

What I usually testify to be my "religion" is agnosticism, a mild meritocratic, somewhat stoic sort. I personally believe that the G-d (whatever meaning we consider) speaks to one through his own reason and conscience and rarely through the mouths of clerics. I generally dislike fanaticism, excessive ritualism, dogmatism and clericalism, and condemn anti-secular, anti-education, anti-ecumenism, anti-sexuality and anti-equality parts. At the same time I think that almost all the religious, esoteric and philosophical teachings, as well as cultures and sciences harbour a piece of divine wisdom so I respect their followers as far as they act peacefully and with respect to others. Among the deadliest sins I condemn are hypocrisy, ignorance and their promotion. Among the key merits I value are intelligence, knowledge and honesty of a person to oneself (and to others of course but being honest to oneself is essential).

Political views

A state policy of my dream is liberal social technocracy. Liberal because people are to be free (while, not to forget, security (including social) is a precondition to freedom), social because taking care of the basic social as well as physical security is the ultimate function of a state and almost the only obvious reason for a state to exist (without it anarchy seems no worse), technocracy because serious things are to be engineered and driven a mindful way, by accordingly qualified professionals.
Education
  • School of Hard Knocks
    present
Basic Information
Gender
Male
Looking for
Friends, Dating, A relationship, Networking
Relationship
Single
Other names
Иван Мащенко, Maščenko, Mascenko, Maschenko, Machtchenko