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attheedgeofscience
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A personal website and an informational resource dedicated to stem cells, tinnitus, advocacy, and life experiences
A personal website and an informational resource dedicated to stem cells, tinnitus, advocacy, and life experiences

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A-first-of-its-kind study employing cord blood stem cells for the treatment of congenital hearing loss in children has ended with positive results for the 11-patient trial. The outcome of the trial matches the results of preclinical studies that likewise indicated stem cells can help reverse hearing loss. The autologous stem cells were administered intravenously – a low-risk intervention.
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For those who like to keep up with tinnitus research, hereby a hand-picked list of emerging treatments that are worth keeping an eye on. The research field is busy with potential treatments for both acute- and chronic-stage tinnitus.
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The AM-101 clinical trial sponsored by Auris Medical seemed to come to a final halt yesterday when it was announced that the TACTT3-study had not met its primary efficacy endpoint for acute inner ear tinnitus. Another earlier phase-III trial (TACTT2) also failed in 2016 which led to modifying the ongoing trial in Europe (also known as "TACTT3"). With this important news, it would appear that some 10 years of work has ended while leaving the tinnitus community without any pharmacological treatment – either now, or in the foreseeable future.
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Eight months ago, I created my website (www.attheedgeofscience.com) and since that time, I have received a number of messages (public and private) asking me for me for information on topics like stem cells, hearing disorders, pharma company updates, and research advocacy. To accommodate all the requests, I have set up a community on Google+ that will go live during February (but you can sign up now if you wish). More about the closed forum can be read via the link, below.

Community Link:

https://plus.google.com/communities/115955081514825572896
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According to an article by The Economist, although homeopathic medicine is known to be ineffective, Americans annually spend three billion dollars on it. Research into cures for conditions such as tinnitus and hearing loss are plagued by low donations from the public (despite their huge prevalence), but instead of contributing to proper science, the average person would apparently rather throw money out the window. In 2005, The Lancet conducted a review of the existing literature of homeopathy ‒ the results can be found here:

www.thelancet.com/journals/lancet/article/PIIS0140-6736(05)67177-2/abstract
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Smoking during pregnancy continues to receive bad press. A recent study concluded that smoking while pregnant may contribute to cerebral palsy in the unborn child. A publication from 2003 indicated that close to 1000 infant deaths per year in the United States alone are attributable to maternal smoking. Despite all the warnings, just one in two expectant mothers quit the habit in the 21st century.
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Lessons from advocacy...
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The +World Health Organization estimates that as many as 1.1 billion young adults are at risk of developing hearing loss - in part - due to increased recreational noise exposure (e.g. mp3-players). The cost to society associated with unaddressed hearing loss is astronomical: some 750 billion dollars annually. Despite these figures, relatively little is being done to develop therapies that would enable regeneration of lost inner ear function. However, a new research topic on just that has recently been launched (see embedded link, below). The research topic is part of the +Frontiers Media Spotlight Award where researchers are competing for a prize worth $100,000:

https://blog.frontiersin.org/2016/11/25/second-annual-frontiers-spotlight-award-announced-for-2018/

Anyone can support the research topics and help them win by sharing the link to the topic itself as well as by sharing any future article published in relation to the subject. Read more via the link, below.
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