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Cell Stem Cell

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Our September issue is online now --> http://ow.ly/RKQTp. This issue’s cover depicts transcriptional snapshots of neural stem cell heterogeneity at single-cell resolution and is a homage to the famous “Horse in Motion” film by Eadweard Muybridge. Check out those studies, regulation of chromatin reorganization to repress transposons in ESCs and during cardiac specification, autocrine signaling loops driving leukemic stem cells and human AML development, and more! #stemcells
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Cell Stem Cell

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Online now: Lee Rubin and colleagues purified and profiled iPSC-derived motor neurons (MNs) derived from spinal muscular atrophy (SMA) patients. This approach helped them understand why motor MNs in these patients are so severely affected, even though the SMA protein is present in other cell types too; MN have hyper-activation of the ER stress pathway, and targeting this response increases their survival http://ow.ly/RwmGY #stemcells
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Cell Stem Cell

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Online Now: Xu lab reports on differential immunogenicity of hiPSC-derived cell types in humanized mice. Smooth muscle cells are immunogenic whereas retinal pigment epithelial cells are immune tolerated (even in non-ocular locations).
http://ow.ly/Re682
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Cell Stem Cell

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Online now: Essers lab finds that within phenotypic HSCs, a subset are megakaryocyte-committed progenitors, and can directly expand in response to inflammation to generate platelets http://ow.ly/RdgoQ #stemcells
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Cell Stem Cell

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Caught in the whirlwind of single cell papers added to your 'must read' list? Need to get a comprehensive overview of this technology and its approaches in stem cell biology? Look no further than our review from Timm Schroeder and colleagues - FREE as part of our Featured Five review collection!
http://ow.ly/R3bE9 #stemcells
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Cell Stem Cell

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Online now: Akashi lab find that autocrine stimulation by TIM-3/Gal-9 regulates self-renewal of human leukemic stem cells (LSCs) through co-activation of NF-κB and β-catenin signaling, and that this mechanism promotes leukemic progression in a range of myeloid malignancies. http://ow.ly/QViTx #stemcells
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Have them in circles
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Cell Stem Cell

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Have you ever felt overwhelmed by thoughts of inadequacy? That you’re not appropriately qualified for your position, or unworthy of received recognition?

You’re not alone. Feeling like an imposter is common, and talking about it helps. Chris shares his story here http://ow.ly/RIrqY
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Cell Stem Cell

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Online now: Ohgushi et al. report that Rho-YAP/TAZ mediated organization of actin microfilaments is a mechanism that connects long-term survival of human embryonic stem cells with the pluripotent state. http://ow.ly/RwnkT #stemcells
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Cell Stem Cell

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Online now: Fernandes lab reports that abnormal accumulation of fat in stem cell niches of the brain is a mechanism that may contribute to development of Alzheimer's disease. http://ow.ly/RtKe9
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Cell Stem Cell

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Just added to Cross Talk, the Cell Press blog: How to nurture the budding scientist in your child by stepping away and not be Dr. Know-it-all. Kerry Evans, senior managing editor at Cell Press, shares her experiences in the kitchen and in the garden. http://ow.ly/Re5KB
A good friend of mine routinely lets her daughter experiment in the kitchen; her daughter has been baking since she was about 7 years old. My friend doesn't worry about whether her daughter mistakes a teaspoon for a tablespoon or deviates from the recipe—the goal isn't a perfectly risen cake or ...
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Cell Stem Cell

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Online now: a second paper reporting on single cell transcriptomes of adult NSCs. In this one, Hongjun Song and colleagues profile hippocampal quiescent NSCs and their immediate progeny, then develop 'Waterfall', a bioinformatics approach to reconstruct trajectories which they show can also be used to analyze single cell datasets for other somatic stem cell populations. http://ow.ly/Ra73Q #stemcells
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Cell Stem Cell

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Are you thinking about whether doing a postdoc is the right thing for you? Read a recent blog post on Cross Talk by Cell Stem Cell Editor Debbie Sweet weighing the pros and cons of this decision http://ow.ly/QVjQt
The latest Future of Research Symposium held in San Francisco prompted a lot of engaged discussion on social media, particularly on Twitter. The topics covered included issues related to funding, career structure, reproducibility, and mentorship and no doubt reflected lively discussion in the ...
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Have them in circles
171 people
Peter van Galen's profile photo
Ajay Abraham (ajayabrams)'s profile photo
Fluidigm Corporation's profile photo
Manash Paul's profile photo
Binnito Charles's profile photo
AzureAH Inc..'s profile photo
Mark Lader's profile photo
Maria del Pilar De la Rosa Ruiz's profile photo
吳清源's profile photo
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Cell Stem Cell is monthly journal from Cell Press launched in June 2007.
Introduction
Cell Stem Cell is an official affiliated journal of the International Society for Stem Cell Research (ICCSR), and is published by Cell Press in Cambridge, MA.  

We drive innovation in science by publishing exciting stem cell research and supporting investigators with resources and tools for connecting and collaborating with their peers.