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Eizellspende Egg Donation
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Eizellspende, Egg Donation, Kinderwunsch, Fertility Treatment
Eizellspende, Egg Donation, Kinderwunsch, Fertility Treatment

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IM VERGLEICH ZUM VERGANGEN JAHR STEIGT DIE ZAHL DER FRAUEN, DIE SICH AUS BERUFLICHEN GRÜNDEN FÜR DAS EINFRIEREN IHRER EIZELLEN ENTSCHEIDEN UM 20 PROZENT AN.
Der folgende Artikel wird anlässlich des Frauenwelttages mit Daten aus CREA veröffentlicht.

- Das Durchschnittsalter der Frau, die sich für das Einfrieren ihrer Eizellen entscheidet liegt beim einem Alter von 34 Jahren, ein ebenso entscheidender Moment in ihrer beruflichen Laufbahn.

-85 Prozent aller Frauen greifen Jahre später nach dem Einfrieren auf ihre Eizellen zurück, um eine Schwangerschaft zu erzielen.

-Spanien ist Annahmestelle für das Einfrieren von Eizellen von Frauen aus dem Ausland.

Valencia, 06. März 2015. Entsprechend der Daten in CREA (Centro Médico de Reproducción Asistida de Valencia) ist die Ziffer der Frauen, die sich für das Einfrieren ihrer Eizellen entscheiden um ihre Mutterschaft herauszuzögern, im vergangenen Jahr um 20 Prozent angestiegen.

Häufig befinden sich die Frauen in einem entscheidenden Moment ihrer beruflichen Laufbahn, schenken dieser Priorität um sich nicht durch die Schwangerschaftsperiode und der Stillzeit einschränken zu lassen. An zweite Stelle rückt der Gedanke an eine Schwangerschaft und wird somit zu einem Zukunftsprojekt.

Das Durchschnittsalter der Frauen, die sich für das Einfrieren ihrer Eizellen entscheiden, liegt bei 34 Jahren, so laut CREA. Hierbei sprechen wir von einem fruchtbaren Alter, welches sich jedoch häufig mit hohen Anforderungen im Berufsleben der Frau überschneidet.

Mehr als 85 Prozent der Frauen greifen Jahre später nach dem Einfrieren auf ihre Eizellen zurück, um eine Schwangerschaft zu erzielen. Die spanische Gesetzgebung setzt keine Altersbegrenzung für die Verwendung der eingefrorenen Eizellen zum Erzielen einer Schwangerschaft auf.

Genau genommen ist Spanien eines der europäischen Länder, welches auf Grund seiner fortgeschrittenen Gesetzgebung und hoher Qualifizierung in den Methoden der Assistieren Reproduktion, an führender Stelle, nicht nur bezüglich des Einfrierens von Eizellen von Frauen zum Herauszögern einer Schwangerschaft, steht, sondern auch Empfänger für Frauen aus dem Ausland sind. In unserem Land bieten wir Ihnen die Möglichkeit ihre Eizellen einzufrieren, was im Herkunftsland durch die Einschränkungen der Gesetzgebung untersagt ist.

Die Co- Direktorin von CREA, Frau Dr. Carmen Calatayud, zeichnet auf wie wichtig es ist, sich darüber bewusst zu sein, dass die Fruchtbarkeit der Frau im Laufe der Zeit abnimmt. Die Eizellen altern und es wird nicht nur schwieriger eine Schwangerschaft zu erzielen, sondern auch die Wahrscheinlichkeit ein gesundes Kind zur Welt zu bringen sinkt. Mit zunehmendem Alter wird der Reifungprozess der Eizellen beeinflusst und ein Scheitern in der Fortpflanzung kann eintreten. Aus diesem Grund wird das Einfrieren der Eizellen vor dem 35. Lebensjahr empfohlen, auch wenn dies nur eine Richtlinie darstellt und in jedem Fall die Eizellreserve der Patientin einzeln betrachtet werden sollte.

Wünscht eine Frau das Einfrieren ihrer Eizellen, werden zunächst hormonelle Blutuntersuchungen, Ultraschalle und ein Pap-Test durchgeführt um die Eizellreserve zu prüfen und Fortpflanzungsprobleme auszuschliessen.

Mit Beginn der Menstruationsblutung wird die Behandlung der Eierstockstimulierung gestartet und mittels Ultraschalle zur Observierung des Follikelwachstums und Bestimmung des genauen Zeitpunkts zur Eizellengewinnnung kontrolliert. Das Absaugen der Eizellen erfolgt unter Sedierung in einem einfachen Prozess durch die Vagina. Im Anschluss friert man die Eizellen zur Aufbewahrung bei 196°C ein, bis die Frau sich entscheidet sie zu verwenden.

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New Strategy May Boost Fertility Clinic Success Rate

Fewer than half of women seeking help from a fertility clinic succeed at having a baby after just one treatment. Now, some researchers believe they have come upon a way to improve those odds.
There is growing evidence suggesting that freezing an embryo after fertilization and thawing it for use in the woman's next monthly cycle leads to higher pregnancy rates, compared with using the embryo immediately. A recent scientific review of three small randomized and controlled studies found that 50% of women got pregnant after receiving in vitro fertilization, or IVF, treatment using a recently frozen embryo. By contrast, women receiving fresh embryos had a 38% pregnancy rate. The review is slated for publication in Fertility and Sterility, the journal of the American Society for Reproductive Medicine.

Data from that and other research are far from conclusive, fertility experts say. But if the evidence holds up in further studies, doctors say that using recently frozen embryos could lead to safer pregnancies and a reduction in complications during delivery. Some clinics and doctors already are gradually making use of more frozen embryos for patients.
Tarek El-Toukhy, a reproductive medicine specialist at Guy's and St Thomas' Hospital in London, which has one of the city's largest fertility units, says the clinic used recently frozen embryos in about 40% of its IVF procedures last year, up from about 25% in 2005. "Freezing will be part of the future of IVF," says Dr. El-Toukhy, who has published findings in this area. "You're making the treatment safer and less hazardous to the mother and perhaps less hazardous to the baby, too," he says.
Whether a fresh or frozen embryo is used is only one factor that affects the success of the complicated assisted fertility process. The chances of getting pregnant through IVF can vary sharply depending on a woman's age and health and factors that include the skill and experience of the clinician and lab staff and the techniques employed at each step of the process.
Researchers are working on other strategies to improve IVF. For instance, Dr. El-Toukhy's team published Monday in Reproductive BioMedicine Online a review of several studies involving a total of 901 women that showed a simple procedure involving scratching the inner lining of the uterus before transferring the embryo appears to double the rate of pregnancy. Dr. El-Toukhy says it is possible the scratch, which causes no ill effects, rallies the body's immune system, which in turn seems to enhance the ability to become pregnant. The researchers are planning a clinical trial to confirm the findings, he says.
With IVF, eggs typically are harvested from a woman who has had trouble conceiving and then fertilized with the man's sperm in a laboratory dish. In order to collect as many eggs at once as possible, women's ovarian follicles are stimulated with certain hormones. The longtime standard has been that one or more embryos are transferred to the woman's uterus immediately while any other embryos could be frozen for future use.
Over time, some doctors began to notice that their patients' pregnancy rates appeared higher when using recently frozen embryos rather than fresh ones. The reason might be that the stimulation of the follicles with drugs containing higher-than-usual levels of hormones, particularly estradiol, negatively impacts the uterine lining. Some women—as many as one in 10, according to the National Institutes of Health—develop a condition from the drugs known as ovarian hyperstimulation syndrome, which has been shown to increase the likelihood of pregnancy complications. By waiting at least one monthly cycle, however, the embryo can be transferred into a more natural uterine environment.
Also possibly contributing to frozen embryos' greater success is that the freezing and thawing process is a tough one to endure, and only the heartiest embryos are likely to survive.
Anja Pinborg, a professor at the fertility clinic at Rigshospitalet, the hospital of Copenhagen University, says that using recently frozen embryos may be most appropriate for certain women, including those at risk of ovarian hyperstimulation. Also, women with few harvested eggs, say, fewer than 15, may not want to risk the embryos not surviving the freezing process, says Dr. Pinborg, who has conducted research demonstrating the boost in pregnancy rate using frozen embryos.
Another important question is the health of children born from frozen embryos. Many studies, such as one conducted by Dr. Pinborg in a study of about 1,000 Danish babies, have found that frozen embryo-born children are as healthy and in some cases healthier than those born from fresh embryos. But Dr. Pinborg noted in her study, published in Fertility and Sterility in 2010, that using frozen embryos increases the chance of newborns being large for gestational age. Though unclear if this leads to negative consequences, being born larger is a known risk factor for later obesity.
Some doctors say using recently frozen embryos could lead to safer pregnancies. Besides avoiding ovarian hyperstimulation, it might discourage the practice of transferring more than one embryo to a woman's uterus, which can create added stress when there are multiple births. If using frozen embryos indeed increases pregnancy rates, and further research is still needed to confirm this, then more clinics and patients might choose a single-embryo transfer.
Miguel Angel Checa, head of assisted reproduction at Spain's Hospital del Mar CIHR Barcelona, co-authored the coming scientific paper in Fertility and Sterility that found higher pregnancy rates with recently frozen embryos. He presented his findings earlier this summer at the annual meeting of the European Society of Human Reproduction and Embryology in Istanbul. Dr. Checa says his review examined three separate randomized and controlled studies involving a total of 633 women with an average age of 35.
Dr. Checa says his clinic now has a policy of freezing all fertilized embryos for women who produce more than 10 eggs. An embryo is then thawed and transferred to the woman's uterus in her next monthly cycle, he says. The health of the egg is the most important factor in boosting pregnancy rates, Dr. Checa says. Still, his greatest challenge in using the freezing technique is persuading women to wait another month before receiving the transferred embryo, he says. "A woman who is waiting one, two years to conceive a baby—she thinks that month I want to be pregnant, I want to be a mother."

source: online.wsj.com
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TODAY'S BOOK SUGGESTION:

Having Your Baby Through Egg Donation
by Ellen Sarasohn, Evelina Weidman Sterling

-- a comprehensive book for people considering parenthood through donated ova, and those supporting them. 

It takes readers through the decision-making process, focusing on questions they are likely to be asking themselves, including: Are we candidates for egg donation? Will it work? 

How much does it cost? How do we find a donor? 

How do we talk about our decision with others? How will we tell our children? Ethical questions related to egg donation are also examined: 

Can a donor truly have informed consent Is it ethically correct for donors to receive payment, and, if so, is the payment for 'time and effort' or for their eggs? 

Hardcover: 384 pages - Click to order/for more info: 
Having Your Baby Through Egg Donation
http://www.amazon.com/dp/1849059071/?tag=pregnancyover40-20

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