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Stojdl Lab
26 followers -
oncolytic, cancer, virus, immunotherapy, tumour, science, uOttawa, CHEO, vaccines, research
oncolytic, cancer, virus, immunotherapy, tumour, science, uOttawa, CHEO, vaccines, research

26 followers
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Proteins that blast away tolerogenic matrix proteoglycans seem to help more T cells get into tumours.

http://bit.ly/2w0wC5o

Image credit: Hope et al 2017 / Journal of Immunology

#cancer #immunotherapy #immunology
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A molecular dissection of CD8+ T cell dysfunction.

http://bit.ly/2w2DFcH

Image credit: Wang et al 2017 / Trends in Immunology

#cancer #immunotherapy #immunology
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MLKL: not just a killer #necroptosis protein any more.

http://bit.ly/2vtJa3s

Image credit: Yoon et al 2017 / Cell Press

#biology
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Host IFNg guides LC3 autophagy proteins to harness GTPases to disrupt #virus replication complexes.

http://bit.ly/2wFVUmi

Image credit: Biering et al 2017
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Sulphated glycosaminoglycans are major functional B cell antigens in human #cancer.

http://bit.ly/2uCtfgj

Image credit: Katoh et al 2017

#OA #immunotherapy
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Let's make precision oncology the standard of care for #cancer patients.

http://bit.ly/2vCE2e3

Image credit: Michael J. Ermarth / FDA via Flickr

#personalisedmedicine #OA
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Encouraging results in this systematic review & meta-analysis of #immunotherapy for lung #cancer.

http://bit.ly/2vuyylL

#OA http://ow.ly/i/xrSVS
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Why do T cells maintain low level, constitutive signaling in their basal state?

http://bit.ly/2wjyq6d

#immunology
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Multiple labs find #SWIFT automated analysis of #flowcytometry #data best at finding rare cells.

http://bit.ly/2wx4faY

#OA

Image credit: Pedersen et al 2017
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Mining the #immune microenvironment to inform #cancer prognosis & #immunotherapy decisions.

http://go.nature.com/2wwHCDE

Image credit: Fridman et al 2017
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