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Stojdl Lab
24 followers -
oncolytic, cancer, virus, immunotherapy, tumour, science, uOttawa, CHEO, vaccines, research
oncolytic, cancer, virus, immunotherapy, tumour, science, uOttawa, CHEO, vaccines, research

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Supramolecular assemblies for macrophage repolarisation and activation in #cancer therapy.

https://go.nature.com/2pPcCgM

#immunotherapy #immunity #immune

Image credit: Mejia et al 2018
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Cool review: our current state of knowledge on how human #DNA viruses are sensed by the host innate #immune system & how viral proteins counteract this immune response.

http://bit.ly/2Pjda9G

#virology #oncolytic #virus #immunotherapy

Image credit: Ma et al 2018
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VSV M51R-M modulates M2 macrophages to a more M1-like phenotype.

http://bit.ly/2OJYJ1i

#cancer #immunotherapy #oncolytic #virus #VSV

Image credit: Rebecca Fuller, 2018
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New models look at how circulating #tumour specific T cells form a linked and connected #immune response across anatomically distant locations.

http://bit.ly/2Nv90tM

#cancer #immunotherapy #immunity

Image credit: Schoenfeld 2018
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Exposing the #virus hiding in your animal facility.

Interesting article with important implications for pre-clinical #research.

http://bit.ly/2NstFhU

Image credit: Roediger et al. 2018
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Strategies for identifying & prioritising synthetic lethal interactions that are robust enough to overcome extensive molecular #tumour heterogeneity.

http://bit.ly/2Nt7KXT

#cancer #immunotherapy

Image credit: Ryan et al 2018
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New #vaccine platform adsorbs peptide onto a PEI and silica microrod to enhance antigen responses during personalised #cancer vaccination.

http://go.nature.com/2IvC3fF

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The landscape of #genome alterations across childhood #cancer.

Cool & study that looks at 961 tumours from children, adolescents, & young adults.

http://go.nature.com/2FXQnij

#OA #immunotherapy #mutation

Image credit: Gröbner et al 2018
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Characterising a class of “alternatively defined neopeptides” may help unravel the rules of tumour antigen recognition.

http://bit.ly/2FPzW4u

#cancer #immunotherapy #neoantigen #immunity

Image credit: Rech et al 2018
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