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Jay Dinan
Attended Denison University
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Jay Dinan

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If you're new to Google+ this is a great cheat sheet of many helpful functions.
H/T +Azlin Bloor 
Google+ Toolbox
I. Google+
. Discover Google+:
. How-To Google+ Videos:
Meet the new Google+: A stream with style and smarts 
Google+: Related Hashtags
Hangouts: Conversations that last, with the people you love
Google+: How to get started <- click
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Google+: Sharing
Google+: Set Up Your Profile
Google+: Find people you know
Google+ Communities: A place for whatever you're into
Google+ Events: Introducing a new way to get together
Google+ Photos: Great photos, in less time
Bring your conversations to life with Hangouts
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. Google+ Support:
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HOA guides:,, , and
Complete Guide to Hangouts for Businesses and Individuals:
. G+ Platform:
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II. Google+ Your Brand / Business
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III. Google+ Teaching 
. Google Plus Posts and Photos - complete guide (updated) (more to come...)
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. Google Plus Tips and Tricks -GPlus Basics - Google Drive Presentations:

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Thanks for resharing Denis's list, +Jay Dinan 

Jay Dinan

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Thanks +Mark Bruce  I like what you said
in your comments:
"These last couple of months it really feels like we've shifted into another gear, our control over matter and biological systems is becoming increasingly sophisticated at a seemingly faster rate." So true.
SciTech #ScienceSunday Digest, 15/14.
Programmable microfluidics, Nanobot computers, stem cell mastery, organ rejuvenation, reinforced graphene, self-assembled films, software radio, atom-photon coupling.

1. Punch-Card Programmable Microfluidics.
A programmable microfluidic system based on the principles of a type of music box that operates with a pattern of holes punched in a paper tape that causes an array of cogs to strike different metal “notes” is deceptively simple yet carries transformative potential & see Stanford bioengineer creates $5 chemistry set. In the device a pattern of holes causes cogs to strike valves in a microfluidic chip interfaced to the device in order to produce a droplet of [1 or 15 different] chemicals that flow along a chip; a suitable pattern of holes can thus produce a desired chain of microfluidic chemical reactions. Applications include synthesising new chemicals from feedstocks, running diagnostic assays, and testing samples. The device can be 3D printed for $5, and the simplicity of the crank and punch card tape could be replaced with an Arduino microcontroller and electric motors for added control and a “limitless” tape length. Combine this with the simple microfluidics from last week and click-linked DNA and future versions might produce any desired DNA sequence in your home for example. 

2. DNA Origami Produced Nanorobots Function as Computer Inside Animals.
That is a headline from the future if ever there was one. Researchers have produced a variety of DNA Origami sequences that self-assemble into different nanorobots capable of interacting with biological substrates, and each other, while inside a living animal and, further, such interactions generate logical outputs capable of switching molecular payloads on or off that were used to build AND, OR, XOR, NAND, NOT, CNOT, half-adder logic gates as part of a functional computational system The system successfully carried out a simple program inside a cockroach and interacted with the insect’s cells. The group believe that they can scale the computational power for such a system inside an animal up to the equivalent of an 8-bit computer like the Commodore 64 and further enhance stability for use in mammals. Future systems will deliver drugs to you in future, based on sensed inputs (your genotype) and releasing the correct output (drug for your genotype and not another). The above microfluidic systems will also produce these DNA origami systems cheaply and in your home should you wish. 

3. Just Two Signals Turn Stem Cells into Embryos.
In a significant advance it has been discovered that just two molecular signals are required to trigger a stem cell to develop into a complete functional embryo are now able to direct embryonic development and formation of tissues and organs by controlling signal locations and concentrations The group plans to replicate the findings in mice before attempting humans and if the mechanisms prove similar then in future we can expect to be able to turn any of our stem cells into any organ that we might need. 

4. Graphene Reinforced with Carbon Nanotubes.
A new processing technique allows carbon nanotubes to be added to sheets of graphene, functioning as reinforcing bars and improving the stability and strength of the overall structure The tubes become covalently bound in many places and were even observed to get thinner when the material was stretched and placed under tension. Many fabrication processes produce imperfect graphene sheets comprised of large domains connected at different angles and the tubes help bridge these interfaces and improve overall conductivity and electrical performance. The group hopes to develop multi-layered versions of “rebar” graphene capable of displacing indium-tin-oxide in many electronic display applications. 

5. Spray-Painting Self-Assembling Nanoparticle Films.
A solvent solution comprising flat nanoparticles - or nanoplatelets - with specific functional groups of either side can be applied to a surface via a conventional off-the-shelf spray can As the solvent evaporates the nanoplatelets connect and self-assemble into a structured film or coating with interesting properties. The proof-of-concept was simply a barrier to oxygen molecules, suitable in gas separation applications. But with different nanoplatelets engineered as photovoltaics, thermoelectrics, LEDs this could possibly lead in future to the ability to spray-paint your roof into one continuous solar panel or your inner walls as huge lighting and digital displays for example. 

6. One Signal to Regenerate & Rejuvenate a Living Organ for the First Time.
The thymus, an organ critical for the development and function of the immune system but whose function rapidly declines with age, has been regenerated and rejuvenated in aged mice for the first time The thymus in the aged mice took on the structure, histology, and gene expression profile of a young and healthy thymus, which began making more T-Cells. Furthermore, this incredible feat was achieved by up-regulating the activity of just a single transcription factor, FOXN1, which instructed stem cell-like cells to rebuild the organ. Further work will test this further before moving to humans and hopefully restoring youthful immune function in compromised patients and elderly people; similar interventions may allow a range of other organs to be restored to youthful function in this way too. 

7. Fruitful Battles Between Software-Defined Radio Algorithms.
A diverse range of software-defined radio algorithms battled it out as part of DARPA’s Spectrum Challenge, aiming to see which algorithm was better able to use a given communication channel in the presence of other users and interfering signals Two different divisions separately tested (i) the ability to send a batch of pre-defined packets on a slice of spectrum on which others are trying to do the same and to simultaneously interfere with and prevent others from doing so; such adaptive radio was obvious military applications, (ii) the ability to optimise data-throughput on spectrum shared with other users, with obvious commercial and consumer applications and benefits. The competition format encouraged rapid innovation; six months ago algorithms typically lacked feedback, spectrum sensing, or adaptation, but they now all exploit these tools. 

8. Massively Improved Communication Channels Between Genetic Circuit Elements.
A significant development in synthetic biology comprises the engineering of much more sensitive, robust, and rapid communication channels between various genetic circuit elements and processors This new platform comprises a tool-set to enable rapid and tunable post-translational coupling of genetic circuits, solving the problem of noisy genetic circuits with limited communication channels and highly variable circuit performance limited by inefficiencies in reusing different parts of a program, and achieves order-of-magnitude improvements in response time. In related news synthetic gene circuits boost the activity of cellular degradation pathways to clear misfolded protein junk, offering a tantalising possibility to treat a range of diseases of the aged

9. The Promise of Enzyme-Powered Microfluidic Micropumps.
A self-powered enzyme micropump has been developed that is able to autonomously deliver small molecules and proteins in response to different stimuli The device functions by anchoring desired enzymes to the surface of a fluidic chip, and the enzymes act as a pump when their substrates are present, setting up a directional flow of fluid through the chip. The proof-of-concept demonstration involved the release of insulin at a rate depending on and proportional to the concentration of glucose; pumping volume is dependent on stimulus concentration; basically an artificial pancreas. The group are expanding the work to incorporate multienzyme cascades and microfluidic logic gates. Future devices might be created with #1 above, and implanted to controllably process any biological molecule as desired. Optimum chemical reaction conditions can now also be easily determined

10. Dual Development of Coupling Atoms and Photons for Quantum Logic.
A group from MIT & Harvard, and another from Max-Planck, have both independently developed the means to precisely couple individual atoms and photons in such a way that might allow the creation of quantum logic gates; and respectively. The former involved trapping a lone rubidium atom close to the surface of a photonic crystal, while the latter involved trapping lone atoms in mirrored cavities, and both enabled the atom to “quantumly” interact with individual photons. Future possible applications could include quantum communications or computation. 

If you'd like notifications of these weekly Digests then just grab the SciTech Digest page here:

+ScienceSunday, with your hosts +Buddhini Samarasinghe, +Rajini Rao, +Chad Haney, +Allison Sekuler, +Robby Bowles, +Carissa Braun, and +Aubrey Francisco!

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That ketamine has made it to human trials is outstanding news. Ketamine's antidepressant effects occur much more rapidly thean traditional antidepressants such as SSRI's. J-
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Jay Dinan

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This was an incredibly expensive and arduous task financed through the Allen Institute. It's a very significant milestone in neuroscience. J-
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Thanks +Cristina De R.Costa  for including me in this eclectic group of people.
Top engagers circle- updated. If you want more valuable followers , people who love Google plus  and are active users posting interesting things, you should  add these people.

Boost your visibility on Google+ sharing this circle!

To be added to my Circle you have to do these simple steps:
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Jay Dinan

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Outstanding...long overdue. Universities and the NCAA make millions off the players. The idea that a player receives a free education in return for playing is a joke. It's a full time job that robs many of the opportunity to get a real education and then discards them when their eligibility is up.
In a potentially game-changing moment for college athletics, the Chicago district of the National Labor Relations Board ruled Wednesday that Northwestern football players qualify as employees and can unionize.
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The idea of paying a player 500 a month is what is a joke. When I signed my letter of intent to play baseball at the University of Illinois. It stated that I will receive 500 a month and prohibited to work in accordance with NCAA. 500 a month is not enough for anyone to live on. Given my educational was absolutely free. Being a Student athlete was incredibly tough. 
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Jay Dinan

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Thanks +Rogerio Manica , I appreciate your hard work in creating and maintaining this circle, and I appreciate being included.
Engagers #4
I am sharing this circle of active engagers, circle sharers, amazing profiles and amazing people to celebrate 15,000 followers. When I left on holidays I had 10,000 followers and even after staying idle for 5 weeks, the number of followers continued to grow. This is impressive. A great week to everybody.
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Thank you +Jay Dinan :)))

Jay Dinan

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Who cuts a birthday cake with an ax.....only in NYC.
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only one person will be eating this cake tonight ;)

Jay Dinan

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Thanks +Mark Bruce for another excellent edition of your Science Sunday Digest.
SciTech #ScienceSunday Digest, 14/14.
Brain mapping, microfluidics, molecular isotope storage, DNA origami boxes, artificial muscles, neuromorphic computing, CRISPR disease cure, metamaterials, manufacturing graphene. 

1. Latest Brain Advances by the Allen Institute.
The Allen Institute for Brain Science announced two big developments this week. First, there was the publication of the first comprehensive large-scale dataset on the wiring of a mammalian brain, created using engineered viruses to trace and illuminate individual neurons in 1,700 mouse brains, the sections of which were scanned at sub-micro resolution to produce a collective average brain connectome map comprising some 1.8 petabytes of data Secondly, the publication of the first major report from the BrainSpan Atlas of the developing human brain, a map of the transcriptome (expression of specific genes in different regions of the brain) across the course of human brain development

2. Simple & Effective Microfluidics with Valves.
I’m really impressed with these deceptively simple microfluidic chip devices made out of double-sided tape cut with channels, a PDMS membrane, and plastic film that include air-controlled valves for the first time This technology allows cheap, functional microfluidic devices to be built in hours rather than days, and can even be used to create chips that fold together into complex three dimensional shapes. Great DIY Bio applications here.

3. Safe Molecular Storage of Radioactive Isotopes.
Small peptides have been made to self-assemble into tiny double-layer spheres containing a hollow cavity that can hold and contain desired radioactive isotopes The radioisotopes of particular interest are those that emit alpha-particles for use in medical research and treatments, and which can breakdown into radioactive daughter ions that end up in undesirable places in the body. These capsules are much more stable compared to those currently used; they don’t break down and were shown to hold onto / contain daughter ions while allowing the release of alpha particles. 

4. Smallest DNA Origami Container with Lockable Door.
The smallest ever DNA origami container has been constructed and contains a door linked to a molecular actuator that controllably, and programmably, pulls the door open and closed The container measures 14nm x 14nm x 48nm and can fit inside the capsid of viruses that could be used for delivery; the door 9nm x 5nm and linked to a programmable segment (lock) of single stranded DNA that coils and contracts when a complementary strand (key) binds. The group seeks other methods of control for the device, the opening of which can release or expose drugs, enzymes, or other molecules at particular sites and times. 

5. Strong, Functional, Implantable Engineered Muscles.
Living artificial muscles have been engineered that closely resemble real muscles, and which contracts powerfully and rapidly, quickly integrates into mice when implanted and even heals itself when in a lab or a mouse The success of this technique depends on well-developed contractile muscle fibers, muscle satellite stem cells and, crucially, creating supportive microenvironment niches for the satellite cells. The result was natural muscle fibers ten times stronger than any previously created, which were imaged and observed via windows implanted into the backs of mice. Great work for repairing & enhancing muscles, and also for lab-grown meat-as-food applications. Related muscle tissue engineering news involved the creation of “mini-hearts” around blood vessels to help pump blood

6. Chip Processing Architectures that Mimic the Human Brain.
This article is a nice overview of the many projects underway that are developing computational systems, chips, and programming languages that mimic or simulate the processing of the human brain - promising future computer systems capable of out-performing human cognition across a range of areas. Such systems are different to the conventional transistor arrays processing 1s and 0s that power our current systems and is worth a read for anyone interested in the space. A new approach not mentioned was this recent prototype neuromorphic photonics chip that carries out basic brain-like computing with light and realises extremely fast information processing and extremely low energy requirements. 

7. A Directional Filter for Light.
A stack of alternative layers of glass and titanium oxide of precise thickness produces a selective light filter that reflects all light except that incident at a particular angle, which is allowed to pass through 80 layers were used in the demonstration device, but by adding more layers the angular selectivity can be made even more precise and narrow. Possible applications include selective filters for telescopes to help view faint objects that are close to bright objects, solar power especially in solar thermophotovoltaics, and possibly even in optical communications. What other applications can you think of for such a directional light filter? 

8. CRISPR Cures Genetic Disease in Living Animals.
For the first time a genetic disease has been cured in living animals via the CRISPR gene-targeting system The liver disease, affecting about 1 / 10,000 people results from a mutation in a single gene that prevents the breakdown of tyrosine. In mouse models a high-pressure injection introduced the CRISPR construct and a correct version of the gene sequence into cells; although only 1 in 250 cells was successfully repaired this way these cells proliferated over the next month at the expense of diseased cells and eventually comprised one third of the liver, enough to functionally cure the disease. The group are investigating improved delivery methods but this is incredibly promising for human genetic disease treatments in the near future. 

9. Cracking Large Scale Visible Spectrum Metamaterial Cloaks.
New nano-transfer printing techniques allow the creation of large area multilayer 3D metamaterials that operate in the visible spectrum Previous techniques were limited to micro-scale areas for such visible metamaterials, but this new printing technique allows for the relatively cheap production of arbitrarily large area metamaterials with negative refractive indices able to bend and cloak visible light. Even the prototype created to demonstrate the technique, at 4” by 4”, shows incredible promise at that scale for producing advanced lenses for cameras, microscopes, and telescopes, better fibers for optics communications, etc. Real invisibility cloaks just took another big step towards realisation. 

10. Samsung’s Graphene Manufacturing Breakthrough.
A new technique developed by Samsung to grow high-quality single-crystal graphene on silicon wafers appears to be a major breakthrough in enabling the mass-production of commercial scale graphene According to Samsung This is one of the most significant breakthroughs in graphene research in history. The process basically uses a standard chemical vapour deposition process to grow a uniform layer of graphene on a germanium-coated silicon substrate; further masking and photolithography processes allowed the creation of graphene field effect transistors (GFETs) and the re-use of the underlying substrate. The realisation of consumer graphene-powered devices just got much closer. 

The weekly SciTech Digests are also available as a Google Newsstand Magazine Edition here: 

+ScienceSunday, with your hosts +Buddhini Samarasinghe, +Rajini Rao, +Chad Haney, +Allison Sekuler, +Robby Bowles, +Carissa Braun, and +Aubrey Francisco 

+STEM on Google+ Community 
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Awesome !!!

Jay Dinan

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I always appreciate the time and hard work that people put into this wonderful community. I hope if you are new to Google plus that you will check them out.
250,000 Members in our Community - Thank You!
We've passed two milestones recently. Firstly, we're actually up to 251.4K members now - and we wanted to thank you, our members! Secondly, we're the 9th largest Community on Google+! That's all thanks to you!

We appreciate your fascinating science posts, your spirited debate and your generous feedback to our fellow members who ask for science input. We'd like to highlight some of our Curator's Choice posts. Further celebrations will follow!

Clockwise from top left:
Physical +John Baez takes us through the physics of the  IceCube Neutrino Observatory (
Science Bytes +Jonathan Stevens demonstrates the complexity of embryo development in a single image.
Life +Michael Habib  explains how some birds rack up thousands of frequent flier miles (
Science Outreach +Jason Osborne discusses Shark Finder, the project providing disadvantaged students with citizen science tools (
Applied +Yonatan Zunger explains the mathematics of how we measure our Universe (
Applied +Joerg Fliege delves into the peculiar prevalence of the p-value, a standard measure in statistics (
Earth +Johnathan Chung provides an amazing science outreach answer explaining the science of the earth's layers (
Applied +annarita ruberto explains the Euler Spiral and its many applications (
Social +M. Laura Moazedi discusses the relationship between perceptions of time and internet use (

Other excellent posts are found in our Policy & Practice category, including a brave account of submitting a retraction of a science paper by +Pamela Ronald   ( In a terrific example of a Science News share +Tommy Leung brings our attention to an example of #ScienceMediaHype , where the media dive into early conclusions on the behaviour of dolphins and puffer fish ( 

Did we miss any of your favourite posts? Tell us below!

#science  #SoG+CuratorsChoice 
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10,293 people
  • Denison University
    Political Science, 1978 - 1982
  • Northfield Mount Hermon
    1975 - 1978
El alma de un poeta con el cerebro de un científico atrapado en el cuerpo de un payaso.
My interest is in the science of Alcoholism,  Addiction, and Recovery with a particular focus on Recidivism.         

From 1988 until 1997 I was a bartender. During this time my alcoholism and cocaine addiction became  much worse and I deteriorated  rapidly  both physically and emotionally.

I was arrested for assault and battery.* 1989

I had three DWI's, two of which I was charged with cocaine possession. 1991, 1993, 1997

I lost my car, condo, job, license and girlfriend.

 I filed for bankruptcy. 1995

I quit drinking and drugging January 22 2000.

AA: I attended AA meetings for the first three years regularly . Being around others who shared a similar problem and goal helped me immensely. The spiritual aspect of A.A. is great, however I began to develop a need to understand from a more physiological/psychological perspective how recovery did and did not work.

THERAPY: This curiosity led me to find a therapist and engage in individual therapy for three years.** This was extremely rewarding, painful and ultimately helpful. I studied therapeutic issues such as transference/counter transference, projection, ego defenses, etc., and schools of thought ( very little Freudian, more self object relations, attachment theory, etc.) in order to understand my underlying developmental deficiencies more clearly.
HOMESCHOOLING: After this I began researching alcoholism, depression and addiction on my own. With no science background, I had a great deal of difficulty reading research papers from Pub Med online. I started exploring neurology, physiology, biology, chemistry, etc. to better understand alcoholism and addiction from a more scientific standpoint.
RESEARCH: Professors at City College of New York up on 138th street have been very kind and allowed me to sit in and audit classes (free of charge) to further my scientific “home schooling” as I like to call it. Another New York University next to where I work  in Greenwich village has not been as kind to my requests to sit in on lectures.


PERSONAL BACKGROUND: My parents were divorced when I was three. I was raised in a single parent alcoholic home with father geographically distant.
Family background: 1 parent is a recovering alcoholic with 2 brothers who committed suicide as adults, a brother and sister who are deceased and were extremely active alcoholics, and a deceased sister with a history of mental illness and nervous breakdowns. The other parent deceased was not an alcoholic but his 2 deceased brothers  were extremely active alcoholics, and his deceased sister  was a relatively high functioning alcoholic. 
WORK: Currently I work  in a restaurant primarily for health benefits and free time to pursue my interest in science.
*The case was overcharged and dismissed on the first court date but it was indicative of a drug and alcohol problem.
**When I started therapy, the co pay was 15 dollars and then increased to 45 dollars per session. I could no longer afford the weekly sessions.
I post primarily on topics related to brain, behavior, and science.
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