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Matthew Jacobs
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Improved Monosynaptic Neural Circuit Tracing Using Engineered Rabies Virus Glycoproteins
We published another paper for those interested! Who among you can truly resist a paper about genetically engineered rabies virus? None, some, a few, all? I actually have no idea how many of you are interested in the real gritty science manuscripts, The pre...

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Three Types of Cortical Layer 5 Neurons That Differ in Brain-wide Connectivity and Function
My very first publication has finally made it through the rigorous peer review process and has been published in the journal Neuron! The paper  Three Types of Cortical Layer 5 Neurons That Differ in Brain-wide Connectivity and Function  can be pulled down f...

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Hobo-Sneak: IPVanish
IP Vanish VPN Service IPVanish is a standard IP masking VPN service that is designed for average users who want some of the benefits of anonymity, or need to mask their geolocation for location aware web services. If you have already read our series on basi...

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A Thought on Self Reflexive Skepticism
Think of something at which you are an expert. Really truly an expert. Try to think about how you feel when you hear a layman talking about that subject. Maybe it's fishing, maybe it's science, maybe it's parenting. It could be the statistics for your favor...

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Hobo-Sneak: Your basic Guide to Anonymity
Hello readers! Over the next few weeks and months I am going to be writing about basic online security. There will be a few different articles on various measures you should be taking to protect your information and perhaps your identity. In this day and ag...

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Wrongness, Rightness, and The Academics who never believed the Earth was flat.
Why should you read this: This post is going to be a little different. I am going to write this one a bit more casually, and that may mean there will be some pg-13 language involved. If you are offended by that type of thing, I apologize in advance. Disclai...

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Facebook wont let me back into the Hobo-Geek page
Facebook has locked me out of the Hobo-Geek Facebook page, and the only way to get back in is to prove somehow that I own this website... Hopefully this will be good enough. Matt Jacobs, Author and Owner of this Website

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The World is Big and Stupid
A few weeks ago I stumbled onto this NPR article  which made me smile. In it, the author points out a quoted piece of text written by Charles Darwin in a letter to one of his friends. The quote reads, "I am very poorly today, and very stupid and hate everyt...

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Mitochondria and Your Other DNA
Why read this? The mitochondrion is, in my opinion, one of the most fascinating and incredible organelles in our cells. Really, I promise that mitochondria are going to surprise you. Stick with me here and I'll try to tell you a story about mitochondria, an...

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Mitochondria and Your Other DNA
Why read this? The mitochondrion is, in my opinion, one of the most fascinating and incredible organelles in our cells. Really, I promise that mitochondria are going to surprise you. Stick with me here and I'll try to tell you a story about mitochondria, an...
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