Scientists Switch Off Brain Cell Death

New hope for brain diseases, like Parkinson's, Alzheimers, in fact, any brain disease that involves brain cell death as a part of the disease progession...


"What's exciting is the emergence of a common mechanism of brain cell death, across a range of different neurodegenerative disorders, activated by the different mis-folded proteins in each disease," said Giovanna Mallucci, who led the research at the University of Leicester's toxicology unit.

"The fact that in mice with prion disease we were able to manipulate this mechanism and protect the brain cells means we may have a way forward in how we treat other disorders," she said in a statement about the work.

An estimated 18 million people worldwide suffer from Alzheimer's, and Parkinson's is thought to affect around one in 100 people over the age of 60. In these diseases, neurons in the brain die, destroying the brain from the inside.

But why the neurons die has remained an unsolved mystery, presenting an obstacle to developing effective treatments and to being able to diagnose the illnesses at early stages when medicines might work better.
http://www.newsdaily.com/stories/bre84509x-us-brain-neurodegeneration/

Original journal article:
http://www.nature.com/nature/journal/vaop/ncurrent/full/nature11058.html
Photo
Shared publiclyView activity