Profile

AboutPostsPhotosVideos

Stream

NFO

Shared publicly  - 
 
Technical details aside, Crispr-Cas9 makes it easy, cheap, and fast to move genes around—any genes, in any living thing, from bacteria to people. “These are monumental moments in the history of biomedical research,” Baltimore says. “They don't happen every day.”

Using the three-year-old technique, researchers have already reversed mutations that cause blindness, stopped cancer cells from multiplying, and made cells impervious to the virus that causes AIDS.
We now have the power to easily alter DNA. It could eliminate disease. It could get really out of hand.
2
Richard Sidler's profile photo
 
here we go!
Add a comment...

NFO

Shared publicly  - 
 
Dengue fever is so excruciating that it is often called the “bone breaker,” causing severe pain in the joints and abdomen, vomiting, and circulatory system failure. It's nearly impossible to treat, so the only way to cut down on incidences of the disease is to decrease the number of mosquitoes that carry it. One startling effective way to do that: genetically modifying mosquitos so their offspring won't survive. A year-long trial with genetically modified mosquitoes in northeast Brazil has been the most successful yet, reducing the population of the disease-carrying insects by 95 percent, according to a study published last week in PLOS Neglected Tropical Diseases
Dengue fever is so excruciating that it is often called the “bone breaker,” causing severe pain in the joints and abdomen, vomiting, and circulatory system failure. It's nearly impossible to treat, so the only way to cut down on incidences of the disease is to decrease the number of mosquitoes that carry it. One startling effective way to do that: genetically modifying mosquitos so their offspring won't survive. A year-long trial with genetically...
1
1
Richard Sidler's profile photo
Add a comment...

NFO

Shared publicly  - 
 
A technology in development at several drug companies offers some hope for a more effective and convenient treatment for the Antonellis, and patients with other serious genetic conditions, such as sickle cell anemia. The technique is called Crispr, which stands for clustered regularly interspaced short palindromic repeats. Crispr, a method for editing the human genome—the complete set of an individual’s genetic material present in any of her cells—allows scientists to cut out faulty sections of DNA that can lead to serious illnesses and replace them with healthy ones. In the two-part process, first an RNA “guide” molecule locates the part of the DNA that needs to be removed or fixed. Then a Cas9 protein attaches to the DNA and cuts out the mutation. In some cases, scientists can then insert a good strand of DNA. Scientists began using Crispr in human cells about two years ago.
A cheap gene-editing method could lead to cures—and frankenbabies
1
1
Richard Sidler's profile photo
Add a comment...

NFO

Shared publicly  - 
 
Neither Knapp nor Whitaker see much of a future for gene editing techniques in enhancing the flavor profile of future strawberry breeds. Besides the complications in marketing anything with a whiff of genetic engineering, flavor is too complicated to engineer in cut-and-paste fashion. “Plant breeding really operates on the entire genome. We don’t have the luxury of working on a gene at a time,” says Knapp. In other words, even though they might be able to isolate a gene responsible for a flavor, they wouldn’t want to breed for it without pulling along all the related genes it blends with as it goes to protein to chemical to mouth-erupting flavor.
Botanists are starting to unravel the insanely complicated genetics of the strawberry's delicious flavor.
1
1
Vittoria Patti's profile photo
Add a comment...

NFO

Shared publicly  - 
 
Will organic farmers and consumers accept ‘rewilded’ plants?

Along with the technical feasibility, the article also tackles the ethical, social and legal implications of whether such rewilded crops would be considered GMOs in various countries and how likely organic farmers and consumers would be to adopt it.

The authors examine this aspect from several angles, first pointing out that ‘rewilding’ with the newer breeding techniques would be compatible with and even contribute positively to the core principles of organic agriculture as set out by the International Federation of Organic Agriculture (IFOAM) including avoiding use of chemicals, contributing to biodiversity and improving environmental quality.

“In current legislations, a plant is considered natural if it’s mutated by chemicals and radiation—that happens in nature,” said David Palmgren, one of the authors of the paper in the press release. “If you can make a precise mutation that has the same effect and you don’t introduce new material, then this type of plant should also be an exception.”
2
Add a comment...

NFO

Shared publicly  - 
 
 
Have you heard of body shaming? Comments like fatso and ugly sum it up. Debbie, an eating disorder survivor and activist, discusses the effects of body shaming. Take a look.
--->How do you react when someone calls you fat or ugly or worse?
---
Body Image Questionnaire and How to Love Your Body and Yourself - http://ow.ly/Nw1z0
Body Image and Self-Esteem - http://ow.ly/Nw1E6
How To Develop Positive Self-Esteem? - http://ow.ly/Nw1Ux
---
In-depth Eating Disorder Articles - http://ow.ly/Nf8gE
Surviving ED Blog - http://ow.ly/Nf8pi
-
Get Trusted Mental Health Information at http://www.HealthyPlace.com
View original post
1
Add a comment...
Have them in circles
5,091 people
Breast Cancer Yoga's profile photo
Bjarke Bakker's profile photo
Judah Paul's profile photo
Mariana Esther Martinez's profile photo
Ontiveros BTX's profile photo
Rune A. Magnussen's profile photo
Hareshkumar Vasava's profile photo
Brooke Baldwin's profile photo
Richard Green's profile photo

NFO

Shared publicly  - 
 
Cell Promotion By Traditional Chinese Herb

In traditional Chinese medicine, many herbs are considered beneficial for cognition improvement. Recently, some natural products derived from herbal medicines have been reported to promote NPC proliferation, elucidating the underlying mechanism for the cognition-enhancing effects of these herbal medicines. Rhizoma Acori tatarinowii (AT) has long been a principal medicine in traditional Chinese formulas for treatment of brain disorders, such as senile dementia, dysmnesia and stroke.

Under the guidance of Professors Pei Gang and Zhao Jian, graduate student Mao Jianxin and Dr. Huang Shichao found that AT-treatment enhanced hippocampal neurogenesis in wild-type and transgenic AD model mice as well as aged mice. Read more from Asian Scientist Magazine at: http://www.asianscientist.com/2015/06/in-the-lab/chinese-herb-promotes-brain-cell-proliferation/
Extracts of the traditional Chinese herb Rhizoma Acori tatarinowii have been shown to boost neurogenesis, at least in mice.
1
1
Daniel J. Stern's profile photo
Add a comment...

NFO

Shared publicly  - 
 
Pollution Caused By Fossil Fuel Burning

Although American air today is the cleanest it has been in four decades, pollution is still a major public health problem. According to estimates from the American Lung Association, more than 46 million Americans — about 15 percent of the U.S. population — are chronically exposed to levels of particle pollution that exceed Environmental Protection Agency (EPA) standards, with a further 44.1 million plagued by periodic unhealthy exposures on bad air days or, as in parts of California, seasonal air pollution spikes. Meanwhile, in some Chinese and Indian cities, air pollution levels are routinely three to six times higher than World Health Organization standards. A recent study in the peer-reviewed journal Environmental Health and Technology estimated that we could avoid 2 million deaths globally by cleaning up the world’s air.
Scientists now suspect that a major cause of dementia could be the air we breathe.
1
Add a comment...

NFO

Shared publicly  - 
 
A special investigation into how the new pig superbug LA-MRSA is spreading onto our plates and into our bodies. Watch the disturbing results of the Guardian's food tests in four of Britain's biggest supermarkets, where the superbug has been found in pork. It's not deadly – but factory pigs overdosing on antibiotics is the latest twist on the long road that, microbiologists warn, will make antibiotics useless.
2
3
Richard Krajewski's profile photoCharlie Ebert's profile photo
Add a comment...

NFO

Shared publicly  - 
 
How to tell a liar (politician) from a normal person


Hank gets into the dirty details behind our lying ways - how such behavior evolved, how pathological liars are different from the rest of us, and how scienti...
1
Add a comment...

NFO

Shared publicly  - 
 
What is venom?

Venom comes in many forms. Some types of venom can attack the brain and nervous system (neurotoxic), while others attack you cell's molecular structure (proteolytic), the cardiovascular system (coagulopathic), or muscle tissue (myotoxic); they can also break down tissue (cytotoxic).

Venom can have any number, or even all, of these compounds. Highly neurotoxic venom is thought to be the most deadly to humans. Other side effects of venom include disruption to blood coagulation by hastening or slowing its flow, causing either haemorrhaging or clotting.

Venom is commonly measured by something called the LD50: the concentration of toxin (lethal dose, mg/kg) required to kill half of a test animal group. A smaller number indicates more concentrated venom, with the most venomous species gaining a rating of less than one.

How lethal the venom is to humans also depends on how the venom is delivered, which is, in turn, influenced by fang size and how much venom is injected (venom yield). Some venom is more dangerous for other animals than for humans, and vice versa.
Australia has plenty of dangerous animals. Here are Australia's 10 most venomous animals that have some of the most lethal venom in the world
1
Add a comment...

NFO

Shared publicly  - 
 
Is Magnesium Missing From Your Diet?

Foods with high magnesium content include dark leafy greens, especially kale, chard, and spinach; tree nuts and peanuts; seeds; oily fish; beans, lentils, legumes, and whole grains; avocado, yogurt, bananas, and dried fruit; dark chocolate; and molasses. Supplemental magnesium is available over the counter in many forms: citrate, amino acid chelate, chloride, glycinate, malate, taurate, carbonate, and others, which vary in absorption, concentration, and bioavailability.
1
1
David Wegmuller's profile photo
Add a comment...
People
Have them in circles
5,091 people
Breast Cancer Yoga's profile photo
Bjarke Bakker's profile photo
Judah Paul's profile photo
Mariana Esther Martinez's profile photo
Ontiveros BTX's profile photo
Rune A. Magnussen's profile photo
Hareshkumar Vasava's profile photo
Brooke Baldwin's profile photo
Richard Green's profile photo
Contact Information
Contact info
Google Talk
https://plus.google.com/u/0/b/101701263979248309987/101701263979248309987/posts
Story
Tagline
#NFO: Brain Health: Brain Research And News = NeuroFerritinOpathy
Introduction
Neuroferritinopathy: or NFO for short, is a genetic disorder which affects the brain.

It is caused by a genetic mutation which affects storage of iron, as ferritin or FTL and causes a buildup of iron as ferritin in the brain. 

It becomes apparent only in Adult life, about 40 to 50 years of age.

It is progressive, meaning that symptoms will worsen over time. (10 to 20 years) 

Although some children have it, this is an infant onset disease which affects them, whereas this type of NFO is Adult onset.

Some individuals develop or have difficulty swallowing (dysphagia). 

Someone who has NFO develops or has a slurred voice. (dysarthria). 

Some people develop or have some balance problems, (vertigo) which can cause them to fall over, or have an unsteady walk or gait but otherwise, they can seem fine to most people. 

Individuals with this condition can get dizzy, and lose their equilibrium, and can fall because of this dizziness...

Progression is relentless, and becomes generalized over a 10 to 20 years period... 

Eventually resulting in aphonia or: Speech problems, mainly slurring of words, Dysphagia or: Difficulty swallowing, which may require a surgical addition of a feeding tube...

Resulting symptoms are severe motor disability with subcortical/frontal cognitive dysfunction or: Memory problems, reduced ability to handle and process acquired knowledge, personality changes (apathy, anxiety, inertia, or depression), and bradyphrenia or: Slowed thought processes... 

Each child of an individual with neuroferritinopathy has a 50% chance of developing this condition...

There is a genetic test which can be performed which can tell if the condition has been passed on to the children of affected people or not... 

The test is a biopsy, which is performed by a doctor and involves removal of a piece of skin from the arm about the size of a matchhead sing a tool which involves no pain and is very fast...

There is currently no cure for NFO or any treatment...
  
Interests: Neurology, Brain Health, Brain Research, Brain Technology, Genetics, Genetics Research, Genealogy, Brain Damage, Brain Disorders, Neuroscience, Psychology, Genetics Education, Synthetic Biology, Telomeres, Glia Cells, BBB, Blood Brain Barrier, Aging Regeneration, anti-aging, anti aging research, biogerontology, biomedicine, brain cell therapy, neuroscience.