When are we going to stop this? The Nazis tried to hid this kind of evil.
Genetic mutations impacting the same target as ezetimibe (Zetia) appear to protect against heart disease, a study found, suggesting that the drug's effect on cholesterol as a surrogate endpoint should be backed up by a hard endpoint benefit.
Drugmaker Merck created consternation about a possible embargo break on its major IMPROVE-IT trial at the American Heart Association meeting by releasing a statement hours before the presentation Monday that the primary endpoint for the addition of ezetimibe to a statin was met for hard endpoints. Then the New York Times actually did break the embargo. See MedPage Today coverage here.
Phase III results with the novel reversal agent andexanet for factor Xa inhibitors, in this case apixaban (Eliquis), showed rapid 94% reversal of anticoagulation in healthy volunteers. See MedPage Today's update on the reversal pipeline here.
A novel treatment for hyperkalemia, zirconium cyclosilicate or ZS-9, outperformed placebo in restoring potassium levels to normal within 48 hours in an open-label trial.
Cardiac resynchronization devices for heart failure were associated with fewer 30-day readmissions, a meta-analysis affirmed.
Mechanical chest compression devices weren't better than standard CPR by paramedics in a real-world British trial.
Atrial fibrillation hospitalizations and emergency visits climbed steeply from 2006 to 2011.
A disease management program for atrial fibrillation kept people alive and out of the hospital longer than did usual care in another study.
Exhausted? There could be a link to heart disease, a meta-analysis suggested.
There's a new journal coming to the heart block this spring, JACC: Clinical Electrophysiology.
Low-molecular weight heparin could help protect hearts and other organs during transplantation, experiments suggested.
Automated phone and mail reminders slightly boosted adherence to hypertension and cholesterol medication by increasing prescription refills, Kaiser Permanente databases suggested.
Looking for a guideline or calculators and tools to help apply it? The American College of Cardiology has a new app for you.
PCI-capable hospitals are only a little more expensive than other centers in treating heart attacks, a Medicare analysis showed.
The health ministry of Rwanda has reversed a decision to screen all travelers from the U.S. and Spain for Ebola, which President Paul Kagame praised in a statement that said the country's health minister "has sometimes acted first and thought later."
The Department of Health and Human Services will be issuing $840 million in grants over the next 4 years to support 150,000 clinicians in developing strategies to improve healthcare quality while holding down costs, the agency announced Thursday.
Karen DeSalvo, the national coordinator for the federal government's health information technology office, is leaving that post to head up the government's Ebola response effort.
Naproxen tablets carrying the Assured brand have been recalled because, due to a "packaging mix-up," they are actually ibuprofen, the FDA said.
In an experiment designed to test extend its "logistical technology," Uber car service offered flu shots to customers for several hours on Thursday.
Australian surgeons have reported the first successful transplantation of a "dead heart."
Retired NFL quarterback Kevin Kolb says lingering effects of multiple concussions "are with him every waking moment."
Be sure to give yourself a break tomorrow on National Forgiveness Day, as a recently published study showed that people who make amends for their wrongdoings find it easier to forgive themselves.
The European Medicines Agency's top advisory committee recommended strengthened warnings on blood clot risk for the leukemia drug Iclusig (ponatinib) but no marketing restrictions. The drug was taken off the market in the U.S. for a few weeks last year before the FDA allowed marketing to resume with new warnings.
It was not the first or most catastrophic blowout visited by Mr. Hamm, a sharecropper’s son who became the wealthiest oilman in America and energy adviser to Mitt Romney during the 2012 presidential campaign. Two years earlier, a towering derrick in Golden Valley County had erupted into flames and toppled, leaving three workers badly burned. “I was a human torch,” said the driller, Andrew J. Rohr.
Blowouts represent the riskiest failure in the oil business. Yet, despite these serious injuries and some 115,000 gallons spilled in those first 10 blowouts, the North Dakota Industrial Commission, which regulates the drilling and production of oil and gas, did not penalize Continental until the 11th.
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High in a Morgan Stanley office tower, Paul B. Kazarian, one of the largest holders of Greek government bonds, was recently trying to persuade a room full of investors that Greece’s debt load of 318 billion euros was actually a tenth that size.
When you use international accounting standards, he declared, “it reduces the value of the debt.” ....
Wiry and intense, Mr. Kazarian can come across as slightly offbeat. With the pink oxford shirts he wears every day, he deploys a plastic pocket protector that holds his collection of six pens and markers. His mien can veer from professorial to a bit manic, especially when he senses that someone is not quite grasping his line of reasoning.
Indeed, when he is working on a deal, there is nothing but the deal. His work days are 20 hours long (sleep comes from 2 to 4:30 in the morning), with breaks taken for morning Mass and a spin on a stationary bike (where he continues to pore over documents).
2. Jury-rigging democracy
3. Did OR get it wrong with oil terminal permit?
4. Paul Allen commits $100M to Ebola
5. Four carbon cap-tax hybrids
6. Who’s painting over national parks?
7. What if you build it, and no one comes?
8. Why millennials don’t drive … and won’t
9. Racial equity can make us richer
10. Fish get more protection than people
This was the play that sealed the deal for the Seattle Seahawks against the Washington Redskins.
Ron Sims was unanimously confirmed by the U.S. Senate on May 6, 2009, and sworn in as the Deputy Secretary for the U.S. Department of Housing and Urban Development on May 8, 2009. As the second most senior official at HUD, Sims is responsible for managing the Department's day-to-day operations, a nearly $40 billion annual operating budget, and the agency's 8,500 employees.
Sims previously served as the Executive for the King County, Washington, the 13th largest county in the nation in a metropolitan area of 1.8 million residents and 39 cities including the cities of Seattle, Bellevue and Redmond.
One of the hallmarks of the Sims Administration in King County was the integration of environmental, social equity and public health policies that produced groundbreaking work on climate change, health care reform, affordable housing, mass transit, environmental protection, land use, and equity and social justice.
Sims is also a proponent of Smart Growth programs and the preservation of green space before it is lost to development. The policies he implemented in King County stopped costly sprawl and resulted in 96 percent of new construction being concentration in urban areas with only 4% in rural areas.
Over the years Sims developed a reputation as a tireless legislator, working on a diverse palette of issues that led to advances in the areas of the environment, education, public safety and the protection of workers' rights. He credits his drive in part with marching alongside his politically active parents in the 1950's and 1960's during the civil rights movement led by Dr. Martin Luther King Jr. Those experiences honed in him a passion for civil rights issues that has been a guidepost throughout his career.
Sims was named Leader of the Year by American City and County Magazine in July, 2008 and was recognized as one of Governing Magazine's Government Officials of the Year in 2007. He has been honored with national awards from the Sierra Club, the Environmental Protection Agency and the National Committee for Quality Assurance. Sims joined Senator Edward Kennedy and California Governor Arnold Schwarzenegger as recipients of the 2008 Health Quality Award from the National Committee for Quality Assurance. Sims and King County are also recipients of HUD's prestigious Robert L. Woodson Jr. Affordable Communities Award for 2005.
Born in Spokane, Washington in 1948, Sims is a graduate of Central Washington University.
- Central Washington UniversityPsychology, 1966 - 1971
- King County, WAKing County Executive, 1996 - 2009