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Applied Biological Materials - abm
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Looking for an easy & controllable way to do #CRISPR #GeneEditing? We have ready-to-go #Cas9 expressing #CellLines!

#Research #CellBiology #Genetics

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For the first time, children were treated with genetically engineered T-cells from another person.

Doctors in London say they have cured two babies of #leukemia in the world’s first attempt to treat cancer with genetically engineered immune #cells from a donor.

In the U.S. and China, scientists are also racing to apply #gene editing to make improved treatments for #cancer and other diseases.

#cellbiology #biotech #genetic

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Scientists from @Harvard use #CRISPR to encode the GIF into the #genomes of living bacteria.

The promise of using #DNA as storage means you could conceivably save every photo you’ve ever taken, your entire iTunes library, and all 839 episodes of Doctor Who in a tiny molecule invisible to the naked eye—with plenty of room to spare.

But what if you could keep all that digital information on you at all times, even embedded in your skin?

#geneticscience #genetic #biotech

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Scientists from @MonashUni develop a new drug delivery strategy that is able to block pain within the nerve #cells.

More than 100 million Americans suffer from chronic pain and this figure is expected to grow, driven by the increased life expectancy, increasing incidence of diabetes and cancer, combined with better survival rates, often leaving patients with severe and poorly treated pain.

The study reveals how a target #protein, long known to be associated with both chronic and acute pain, works within the nerve #cell. This protein is the NK1 receptor, the receptor of the neuropeptide substance P, which mediates pain transmission.

#cellbiology #proteinscience #biotech

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The collaboration of five of the UK’s top institutions have provided the potential cure for #HIV.

The clinical trial focuses on a drug called vorinostat, which awakens HIV-infected reservoir #cells. Hopefully, the immune system will then recognize and kill the infected cells with the help of two vaccines.

The first individual to complete the trial, a 44-year-old male, appears to have no trace of the #virus in his bloodstream. However this is most likely due to the ART (Antiretroviral Therapy) treatment he received in combination with the new therapy, so it is too early to claim this is a cure. It will only be clear if he is fully virus-free when the ART fades in a few months.

#biotech #cell #cellbiology

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Scientists use the #CRISPR #gene-editing system & modified #virus to kill #antibiotic-resistant #bacteria.

Initial tests have saved mice from antibiotic-resistant infections that would otherwise have killed them.

But the development of phage therapy has been slow, in part because these viruses are naturally occurring and so cannot be patented. Bacteria can also quickly evolve resistance to natural phages, meaning researchers would have to constantly isolate new ones capable of defeating the same bacterial strain or species.

#biotech #geneticscience #genetherapy

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First clinical trial employing #CRISPR #gene editing technology within the human body will initiate in China.

Scientists there will seek to use CRISPR and #TALEN, another gene editing method, to treat persistent #HPV infection and disable the tumor growth mechanism in infected cells.

In a non-invasive approach, scientists will deliver the necessary #DNA for gene editing via a gel to the cervixes of 60 women between the ages of 18 and 50.

#genetic #geneticscience #biotech

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Who wants this T-shirt? Enjoy your weekend!

#sciencejoke #sciencefunny #biology


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#CRISPR Cas9-How to perform a CRISPR Knockin Experiment?

#Biology #Academia #Research #cellbiology #cell

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The faster and more precise #cancer care is approaching. @US_FDA approved the first #NGS based test for hospitals.

The traditional way of screening for the most common mutation, then try that drug. If it doesn’t work, screen again and try something else. It can take weeks or even months to find a treatment that clicks, taking time patients don’t have.

This new test can tell you how different drugs will work for you, based on the #genetic makeup of your tumor. And it only takes four days to get back results.

#biotech #geneticscience #gene
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