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William J.
Works at Studio Tucano
Lives in Milano
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A subway-style map of the solar system with the change in velocity needed at each point.
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L+150: Logbook

Hey, I didn’t forget that I promised to talk to you about the NATO experiment!

On Wednesday I wrapped up NATO by removing the experiment containers from the Kubik incubator and putting them into the MELFI freezer, their biological state being frozen until researchers on the ground can get hold of them and do their post-flight analysis.

The full name of the experiment is Nanoparticles and Osteoporosis and, like Osteo-4 from the last logbook, it studies the bone. But while Osteo-4 is interested in determining the mechanisms that make us loose bone mass in microgravity, NATO want to see what we can do about it and, in particular, if a particular type of nanoparticles could be effective in counteracting bone loss.

See, it’s not very intuitive, but bone is a living tissue that is constantly destroyed and reformed. Cells called osteoclasts destroy bone, other cells called osteoblasts produce new bone. As long as destruction and production are in balance, everything is good, but in weightlessness this balance is disturbed and osteoclasts win. That’s also what happens when people suffer of osteoporosis, unfortunately a common problem!

NATO observes in vitro the effects of adding to bone tissue  various doses of “strontium-containing-hydroxyapatite-nanoparticles”, or nHAP-Sr. Some ground studies have suggested that adding nHAP-Sr could be effective in impeding osteoclasts in their bone-destructing job, which would promote a more favorable balance in the bone destruction/production cycle. A promising research for us astronauts in space and for people on the ground suffering from bone loss!

But it’s not science all the time up here of course. We do need to keep the Station up and running, which also means periodically changing the Recycle Tank in our Urine Processing Assembly, or UPA. You can see the UPA in the picture, it occupies the deck area beneath our space toilet. What’s left of our urine after being processed in UPA, a dense greenish and not-so-pleasant-smelly liquid called brine, is collected in the recycle tank, which of course needs to be swapped when full.

But I did end the day with another cool new experiment called Nematode muscle. I’ll tell you all about it next time!

Futura mission website (Italian): Avamposto42
avamposto42.esa.int

#SamLogbook #Futura42  

(Trad IT)  Traduzione in italiano a cura di +AstronautiNEWS 
qui: http://www.astronautinews.it/tag/logbook

(Trad FR) Traduction en français par +Anne Cpamoa  ici: https://spacetux.org/cpamoa/category/traductions/logbook-samantha

(Trad ES) Tradducción en español por
+Carlos Lallana Borobio
http://laesteladegagarin.blogspot.com.es/search/label/SamLogBook

(Trad DE)  Deutsch von http://www.logbuch-iss.de
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Internet non è solo un veicolo: è condivisione del sapere. La rete è innanzitutto un concetto filosofico
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William J.

commented on a video on YouTube.
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Togliete quel cazzo di simbolo di Rifondazione Comunista dal video.
Oggi come oggi  è come sputare sul ricordo del Comandante Che Guevara.
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Wembley Stadium timelapse
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inquietante
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Google penalizza My Social Web: ecco cosa è successo e come uscire dalla penalizzazione
Il web è pieno di sudiciume e le serp traboccano di guano a destra e a manca. E che succede? Google penalizza +My Social Web 

Questo quanto riporta +Riccardo Esposito.
Dal punto di vista Seo il caso è carente di tante informazioni, ma qui il problema non è Riccardo o le sue conoscenze seo, non è My Social Web o la sua strategia editoriale, qua il problema è Google.

Quindi cosa fare dal punto di vista seo per evitare questo tipo di segnalazioni negli strumenti per webmaster di Google?
Eliminiamo per sempre tutti i link? 
Vediamo come se la cava poi Google?
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Quando Google penalizza c'è poco da aggiungere. Anche quando a farne le spese è un povero cristo? Siamo sicuri? Io ho vissuto l'esperienza.
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[ ‪#‎CSS3‬ ‪#‎Flexbox‬ ] Impariamo a padroneggiarlo al meglio :)
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take an interactive tour through all the major features of the new flexbox CSS property.
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William J.

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L+149 Logbook

Another day of science yesterday here on humanity’s outpost in space!

First, you’ll be happy to hear that the BRICs I talked to you about in the last logbook are happily chilling out at -98deg Celsius in one of our MELFI freezers: after I activated the experiment on Monday, the microbial cultures remained at ambient temperature for about 24 hours and then it was time to put them in cold stowage, where they’ll remain until they can be returned to Earth.

Yesterday I also performed the third and last run of the Osteo-4 experiment, which came up on Dragon last week. It’s a set of three trays, each one hosting three bioreactors with a culture of mouse bone cells. The aim is to investigate the mechanism of mechano-transduction, which basically means that bones tissue “senses” mechanical forces and responds with a particular behavior. That’s probably why we lose mass in space: in weightlessness there isn’t much load on or skeleton, so the response of our body is to reduce bone mass. If we only could convince our body that we’ll go back to Earth within a few months and all that bone mass will come in handy! To try and send that message we put mechanical stress on our bones by working out every day on a machine, ARED, that simulates weightlifting.

Anyway, back to our experiment, the point is to study gene expression in osteocytes in microgravity: that’s because osteocytes, which are the most common cells in bone, are the mechanosensors of the bone; they are responsible for sensing mechanical loads and inducing appropriate biological responses. How this mechanism works, however, is still a bit of a mystery. Here comes Osteo-4 into play!

As for my contribution, my job was to remove the bioreactors from the trays they are installed in, to  reconfigure the ducting to close all the loops and then put the bioreactors in cold stowage. What made it a bit more cumbersome than it otherwise would be is that, as you can see in the picture,  I had to work in the disposable glovebox… my good old friend from the fruit flies experiment, remember?

Futura mission website (Italian): Avamposto42
avamposto42.esa.int

#SamLogbook #Futura42  

(Trad IT)  Traduzione in italiano a cura di +AstronautiNEWS 
qui: http://www.astronautinews.it/tag/logbook

(Trad FR) Traduction en français par +Anne Cpamoa ici: https://spacetux.org/cpamoa/category/traductions/logbook-samantha

(Trad ES) Tradducción en español por
+Carlos Lallana Borobio 
http://laesteladegagarin.blogspot.com.es/search/label/SamLogBook

(Trad DE)  Deutsch von http://www.logbuch-iss.de
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L+148: Logbook

Busy day of science and logistics for me to start the week.

Dragon unpacking continues, yesterday I had one hour of transfer ops on my schedule. Looking at Dragon you may think we have made quite some progress already in the unpacking, but in reality we have cheated a bit. Many bags have been retrieved and temporarily stowed on ISS, so that we could access other cargo with urgent science. But of course, they won’t unpack themselves…  and some of them are huge, believe me. We call them MO bags and I could comfortably fit inside the smallest of them!

Today I also dealt with a special type of cargo, the Polar fridges. They need to be transferred to ISS, but since they are powered up inside Dragon and contain refrigerated goods and science samples, they need to be moved and reinstalled quickly, to minimize the time they remain unpowered.

Also today I had two science activities for the experiments BRIC 21 and Synthetic Muscle. BRIC stands for Biological Research in Canisters: you can see one the BRIC units in the picture.

This particular run investigates microbes and how they adapt to the space environment, with special attention to the development of antibiotic resistance. You’ve probably heard that this is quite a source of concern in healthcare these days and we really need to understand better how pathogens become resistance to antibiotics.

Doing research with pathogens on ISS carries some complications, because you need to provide the microbial culture with a growth medium: if the crew has to do this manually, as it’s often the case, the operation has to happen in the glovebox to ensure containment of the hazardous microorganisms. Here’s where BRICs come in handy: using a dedicated tool, as you can see in the photo, astronauts can push a piston and inject the necessary mediums without ever breaking the three levels of containment required by ISS safety standards. It’s very quick and efficient!

But I bet you want to hear about Synthetic Muscle… well, turns out that Dragon brought us some samples of a special material that could be used to replicate muscle tissue. It’s an electroactive polymer: you can make it contract and expand by applying different electric currents. It sure sounds a lot like muscle to me, doesn’t it?

Applications on Earth are in the field of prosthetics, of course, but we’re also testing how this material reacts when exposed to cosmic and solar radiation up here, because it could potentially be used in robots to enhance their mobility. Cool, ah?

Futura mission website (Italian): Avamposto42
avamposto42.esa.int

#SamLogbook #Futura42  

(Trad IT)  Traduzione in italiano a cura di +AstronautiNEWS 
qui: http://www.astronautinews.it/tag/logbook

(Trad FR) Traduction en français par +Anne Cpamoa  ici: https://spacetux.org/cpamoa/category/traductions/logbook-samantha

(Trad ES) Tradducción en español por
+Carlos Lallana Borobio aqui: http://laesteladegagarin.blogspot.com.es/search/label/SamLogBook

(Trad DE)  Deutsch von http://www.logbuch-iss.de
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Animali che si drogano - Mente Digitale
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Ebbene sì: anche gli animali ingeriscono piante con effetti allucinogeni (o altre sostanze potenzialmente tossiche) a scopo depurativo o alimentare. In primis parlo dei felini a noi più noti, i gat...
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Bellissimo, complimenti!
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World-record current in a superconductor

The CERN Superconductors team recently obtained a world-record current of 20 kA at 24 K in an electrical transmission line (pictured here) consisting of two 20-metre long cables made of Magnesium Diboride (MgB2) superconductor: http://home.web.cern.ch/about/updates/2014/04/world-record-current-superconductor.

This result, in the framework of the High-Luminosity LHC project, makes the technology a viable solution for long-distance power transportation.

Image © CERN - for terms of use see http://cern.ch/copyright
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I loghi aziendali?Meglio a colori!Un'infografica ci spiega quali usare
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***The award-winning stunning first person zombie shooter is back! ***Join the new sequel to Dead Trigger, the popular hit with more than 23

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Finale del Working Capital a Milano.

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Da ciò che ho potuto vedere su Facebook, in molti si sono sorbiti lo sfrantumamento di palle hanno seguito con interesse l’operazione di “ra

Arcane Legends
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Play the Biggest Co-Op RPG with Pets for FREE!"A Hack And Slash Home Run" - ForbesExperience Adventure Unleashed and team up with friends fr

Tom & Jerry Mouse Maze FREE!
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Feline frenzy with the lovable cartoon duo Tom and Jerry!Help Jerry dodge Tom's rampaging cat attacks and grab some tasty cheese along the w

ITALIA- IL DECRETO LIBERALIZZAZIONI NASCONDE LA TRAPPOLA SUL NUCLEARE
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E’ BREVE MA PREGNANTE IL COMMA Che nel decreto sulle liberalizzazioni, il governo Monti ha pensato bene di dedicare alla scottante questi

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L'asteroide che ha sfiorato la Terra all'improvviso
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Scoperto pochi giorni prima del passaggio ravvicinato, è arrivato a 5 milioni di chilometri dal nostro pianeta. [Video] (ZEUS News)

Prey Anti-Theft - Apps on Android Market
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Track down your lost or stolen phone or tablet. Open source, cross-platform anti-theft tracker. Prey lets you keep track of *all* your devic

Assassin's Creed 3 screenshot e spoiler | Lega Nerd
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NESbox – Emulatore NES online
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“Mondo Pizza”! Cit. Su NESbox.com avete la possibilità di giocare online ai cari e vecchi titoli con cui ci dilettavamo ai tempi dei nobili

Larry, Epic win.
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Poco più di un anno fa sharavo questo famoso Stevey’s [...]

Il Canyon più profondo del sistema solare è su Marte: 11Km
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Stretching across the equatorial Martian highlands for some 2,485 miles [...]

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Ci ho festeggiato il compleanno. DIVERTENTISSIMO! :D
Food: Very GoodDecor: ExcellentService: Excellent
Public - 2 years ago
reviewed 2 years ago
Abbiamo speso 18 euro per un bicchiere di vino (scadente) una birra ed un piattino (misero) di patatine. Mai più. Ah, il calcio balilla costa 2 euro a partita, allucinante. Peccato perchè il posto ha grandi potenzialità non sfruttate per la malattia del soldo.
Atmosphere: GoodDecor: GoodService: Poor - Fair
Public - 2 years ago
reviewed 2 years ago
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