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Vangelis Simeonidis
Works at Luxembourg Centre for Systems Biomedicine
Lives in Seattle
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Vangelis Simeonidis

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My yearly post about impact factors. New Page V post:
It's that time of year again, when I post my list of selected impact factors. Controversial as impact factors are, they remain the main way in which journal quality is judged. The higher the impact factor, the more sought aft...
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Vangelis Simeonidis

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The Geoffrey Beene Foundation Alzheimer’s Initiative is running their second online innovation challenge. The 2013 Geoffrey Beene Global NeuroDiscovery Challenge is a worldwide scientific competition to come up with new research ideas on the search for gender based differences In Alzheimer’s Disease. The winning submission will receive a $50,000 award for research.

My good colleague at the Luxembourg Centre for Systems Biomedicine, Enrico Glaab, is not only participating in the challenge, but has made it into the final round of the competition, and has a good chance of winning it. If you have a few seconds, please go to the Geoffrey Been Challenge website (link below) and show your support for Enrico Glaab. Just follow the links for "Scientific Community" or "Citizen Scientists" and vote for the project entitled: Male/Female Differences in Aging Brains in a Gene For Ubiquitin-Specific Peptidase 9 (USP9) as a Possible Cause for Increased Incidence of Alzheimer’s Disease in Older Women.

Everyone gets one vote every day until the 5th of November, so it would be great of you to come back and vote again, if you agree that Enrico deserves to win.
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A new article, published with my old MCISB colleagues.

A model of yeast glycolysis based on a consistent kinetic characterisation of all its enzymes

We present an experimental and computational pipeline for the generation of kinetic models of metabolism, and demonstrate its application to glycolysis in Saccharomyces cerevisiae. Starting from an approximate mathematical model, we employ a “cycle of knowledge” strategy, identifying the steps with most control over flux. Kinetic parameters of the individual isoenzymes within these steps are measured experimentally under a standardised set of conditions. Experimental strategies are applied to establish a set of in vivo concentrations for isoenzymes and metabolites. The data are integrated into a mathematical model that is used to predict a new set of metabolite concentrations and reevaluate the control properties of the system. This bottom-up modelling study reveals that control over the metabolic network most directly involved in yeast glycolysis is more widely distributed than previously thought.

http://www.sciencedirect.com/science/article/pii/S0014579313005012
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Vangelis Simeonidis

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Please vote for our colleage, Enrico Glaab, to win the Geoffrey Beene Challenge. Your support is very appreciated!
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The poster +Alexey Kolodkin and I have prepared for the ISMB/ECCB 2013 conference in Berlin is now online. Check it out if you are interested: http://www.slideshare.net/vangos7/ismb13-poster-o120-modeling-cellular
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We have announced a position for a PhD student who will work on building models of human metabolism in order to study the role of iron and reactive oxygen species (ROS) in Parkinson’s disease. The student will be based at the Luxembourg Centre for Systems Biomedicine, with regular visits to the Manchester Centre for Integrative Systems Biology. For details and to apply:
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"We're finding out with how little wisdom the world is governed, one Excel error at a time."
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Denis Noble on the importance of actively supporting research funding.
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In his circles
124 people
Have him in circles
113 people
Zhuo Wang's profile photo
Shuyi Ma's profile photo
Zeeshan Sattar's profile photo
Ettore Murabito's profile photo
David Nickerson's profile photo
Andrew Magis's profile photo
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  • Luxembourg Centre for Systems Biomedicine
    2010 - present
  • University of Manchester
    2006 - 2010
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Network Analysis in Systems Biology
www.coursera.org

Network Analysis in Systems Biology is a free online class taught by Avi Ma’ayan of Icahn School of Medicine at Mount Sinai

ISB Researchers Unlock Molecular Signatures of Endometrial Cancer Subtyp...
isbmolecularme.com

nature_tcga_microscope. By Aaron Brooks ISB News Team. May 1, 2013 — Endometrial cancers affect many women in the United States. In 2012, 47

How Do You Cite a Tweet in an Academic Paper?
www.theatlantic.com

There are rules for these sorts of things. They are how civilizations are built and maintained.

Comedy without borders: Eddie Izzard and the language of standup
www.guardian.co.uk

British comedian aims to deliver his show in French, German, Spanish, Arabic and Russian

Yeast, More Interesting than your Parents Think : Saccharomyces Genome D...
www.yeastgenome.org

Are you tired of getting asked why you study yeast? And having your grandma's eyes glaze over when you try to explain your latest research r

Social Media for Science Outreach – A Case Study: Can a research Institu...
www.nature.com

To tie in with this month's SoNYC birthday celebrations, we are hosting a collection of case studies that discuss how social media can be us

The Great Debt Delusion: How Math Keeps Proving Austerity Wrong
www.theatlantic.com

The austerians' foundational text lost a battle with Excel -- and reality

This Is the Reality of Austerity: Greek Children Are Starving
www.theatlantic.com

Force-feeding Greece with budget cuts and tax increases gets a predictable, and tragic, result

Greece launches manhunt after 200 immigrant farmworkers are shot at and ...
www.independent.co.uk

The increasing severity of racist attacks in Greece is under renewed scrutiny after immigrant farmworkers in the west of the country were sh

The Price Lab at the Institute for Systems Biology
plus.google.com

Our research is focused on developing and applying computational tools to study the complex interactions among the many genetic and molecular components that give rise to emergent phenotypes.

Frontiers | Mechanistic modeling of aberrant energy metabolism in human ...
www.frontiersin.org

Frontiers | Mechanistic modeling of aberrant energy metabolism in human disease | Frontiers in Computational Physiology and Medicine publish

Main Page - SBML.org
sbml.org

SBMLToolbox 4.1.0. (21 Jan.'12) The latest SBMLToolbox supports the 'fbc' flux balance constraints package for SBML Level 3. lib

Amanda Ramsey
aramsey.zumba.com

My name is Amanda Ramsey and I am a very enthusiastic Zumba instructor! I have been taking Zumba Classes since 2008 and fell madly in love w

Golden Dawn party infiltrates Greece's police, claims senior officer - v...
www.guardian.co.uk

A senior police officer claims successive governments in Greece allowed the ultra-nationalist Golden Dawn party to infiltrate the country's

Fear and loathing in Athens: the rise of Golden Dawn and the far right
www.guardian.co.uk

In austerity-ravaged Greece, neo-Nazi party Golden Dawn is on the rise. Their MPs give fascist salutes, while on the streets black-shirted v

Kolodkin et al ICSB2012 poster 451B
www.slideshare.net

A kinetic model and design principles study of cellular ROS defence and its failure in Parkinson's disease. Alexey Kolodkin, Evangelos Simeo

As much as you can
www.pagev.net

My favourite Cavafy poem is a slightly obscure one. It has always spoken to me on a deeply spiritual level. As much as you can. by C. P. Cav

International Letter & Petition to Asma al-Assad
www.youtube.com

Women from around the world, urge you, Asma Al-Assad, to take up your responsibility as wife of the Syrian leader. Hundreds of children in y

YouTube - The Muppets: Bohemian Rhapsody
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Create AccountSign In. Home. BrowseMoviesUpload. Hey there, this is not a commercial interruption. You're using an outdated browser, whi