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Researchers at University of California San Diego School of Medicine and Veterans Affairs San Diego Healthcare System say existing screening tools for mild cognitive impairment (MCI) result in a false-negative error rate of more than 7 percent in a new study. These persons are misclassified as not having MCI based on standard screening instruments but actually do have MCI when more extensive testing is conducted. Read more about how this can impact people at risk for Alzheimer's disease here: http://health.ucsd.edu/news/releases/Pages/2016-05-23-current-screenings-miss-persons-with-mild-cognitive-impairment.aspx
#neuroscience #neuropsychology #alzheimersdisease #ucsdhealth #screeningtools  
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Immunology – and the idea that many diseases can best be addressed by boosting the body’s own immune response – is one of the hottest areas in medical research and clinical treatment. University of California San Diego School of Medicine and Chiba University School of Medicine in Japan have announced a new collaborative research center to investigate the most promising aspects of immunology, especially the area of mucosal immunology, and to speed development of clinical applications.
#immunology #research #microbiology #ucsdhealth #collaboration  
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IBM's World Community Grid  and scientists from Brazil, the Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego, and Rutgers New Jersey Medical School have launched OpenZika, a project to find drug candidates to treat Zika, a fast spreading virus that the World Health Organization has declared a global public health emergency. Read more and learn how you can become a "citizen scientist" here: http://health.ucsd.edu/news/releases/Pages/2016-05-19-uc-san-diego-joins-world-community-grid-for-zika-treatment.aspx
#WorldCommunityGrid #openzika #zikavirus #citizenscientist #ucsdhealth  
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Immunization with Bacteria Promotes Stress Resilience, Coping Behaviors in Mice: Approach also prevents stress-induced symptoms of inflammatory bowel disease

Injections of the soil bacterium Mycobacterium vaccae promote stress resilience and improve coping behaviors in mice, according to a new study led by researchers at University of California San Diego School of Medicine and University of Colorado Boulder. The researchers also found that M. vaccae prevented stress-induced colitis, a typical symptom of inflammatory bowel disease, suggesting that immunization with the bacteria may have wide-ranging health benefits. Read more here: http://health.ucsd.edu/news/releases/Pages/2016-05-16-immunization-with-bacteria-promotes-stress-resilience.aspx
#microbiome #gastroenterology #ibd #bacteriology #cubolder #ucsdhealth
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Diabetes Drug Found No Better Than Placebo at Treating NAFLD: A diabetes medication described in some studies as an effective treatment for nonalcoholic fatty liver disease (NAFLD) works no better than a placebo, report researchers at University of California San Diego School of Medicine, after conducting the first randomized, double-blind, controlled clinical trial of sitagliptin, an oral antihyperglycemic marketed by Merck & Co. under the name Januvia. Read more here: http://health.ucsd.edu/news/releases/Pages/2016-05-12-diabetes-drug-no-better-than-placebo-for-nafld.aspx
#nafld #liverdisease #placebo #drugdevelopment #ucsdhealth  
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Family planning is a major health issue in India, the world’s second most populous country. Researchers at University of California San Diego School of Medicine describe a novel program that involves increased male engagement and gender-equity counseling to measurably improve contraceptive practices and reduced marital sexual violence.
#partnerviolence #sexualviolence #familyplanning #contraception #publichealth #ucsdhealth  
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CIRM Grants May Fund the Next Great Stem Cell Achievement: Three UC San Diego researchers receive funding to pursue “great ideas”

All scientific achievement begins with an idea. Yesterday, three researchers at University of California San Diego School of Medicine were awarded funding by the Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine (CIRM) to pursue budding ideas that might eventually impact the field of human stem cell research. Learn about the projects that recieved funding here: http://health.ucsd.edu/news/releases/Pages/2016-05-20-CIRM-inception-awards.aspx
#stemcells #CIRM #regenerativemedicine #ucsdhealth  
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High Levels of Protein p62 Predict Liver Cancer Recurrence: Study in mice and human tissues suggest new prognostic and therapeutic approach

Researchers at University of California San Diego School of Medicine and Sanford Burnham Prebys Medical Discovery Institute have discovered that high levels of the protein p62 in human liver samples are strongly associated with cancer recurrence and reduced patient survival. In mice, they also found that p62 is required for liver cancer to form.
#cancer #livercancer #biotech #sbpdiscovery #ucsdhealth  
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Blocking Known Cancer Driver Unexpectedly Reveals a New Tumor-Promoting Pathway: Targeting both pathways with drug inhibitors more effective in stopping colorectal cancer growth

While investigating a potential therapeutic target for the ERK1 and 2 pathway, a widely expressed signaling molecule known to drive cancer growth in one third of patients with colorectal cancer, University of California San Diego School of Medicine researchers found that an alternative pathway immediately emerges when ERK1/2 is halted, thus allowing tumor cell proliferation to continue. Read more here: http://health.ucsd.edu/news/releases/Pages/2016-05-17-blocking-cancer-driver-reveals-tumor-promoting-pathway.aspx
#colorectalcancer #cancer #gastrointestinalcancer #ucsdhealth  
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Today, The White House Office of Science and Technology Policy is launching a National Microbiome Initiative. The announcement puts the spotlight on UC San Diego’s Center for Microbiome Innovation, a key participant in this effort. Read more: http://health.ucsd.edu/news/releases/Pages/2015-05-13-uc-san-diego-participates-in-white-house-national-microbiome-initiative.aspx
Watch the live webcast at 10 a.m. PT: www.whitehouse.gov/live  
#thewhitehouse #nationalmicrobiomeinitiative #microbiome #americangut #ucsd #ucsdhealth  
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Program to test effectiveness of deputies using drug and referring victims to treatment center -  Drug-related overdoses are the leading cause of injury-related deaths in the United States, surpassing motor vehicle accidents at 44,000 fatalities annually. In response, researchers at University of California San Diego School of Medicine have partnered with the San Diego County Sheriff’s Department to implement and study a program that requires all deputies carry and be trained to use a life-saving drug in the event of a discovered overdose and then refer victims to a treatment center once they are revived.
#opioidabuse #overdose #emergencymedicine #addiction #ucsdhealth #sdsheriff  
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Brazilian Zika Virus Strain Causes Birth Defects in Experimental Models: First direct experimental proof of causal effect, researchers say

Researchers at University of California San Diego School of Medicine, with colleagues in Brazil and Senegal, have described the first “direct experimental proof” that the Brazilian strain of Zika virus can actually cause severe birth defects. Read more here: http://health.ucsd.edu/news/releases/Pages/2016-05-11-brazilian-zika-virus-strain-causes-birth-defects-in-mouse-model.aspx
#zikavirus #infectiousdisease #mosquitoes #ucsdhealth  
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UC San Diego Health is widely recognized as one of the premier health care systems in the United States. We’re the only academic health system in San Diego. It’s the one place that can offer you and your family medical treatments not available elsewhere in the region. And we don’t just treat disease – we treat you.

UC San Diego Health is consistently ranked among the nation’s best hospitals in U.S. News & World Report, and number 1 in San Diego in the magazine’s first-ever metro rankings in 2011. We were honored as one of the top 15 teaching hospitals in the country by Thomson Reuters in 2010.

Our physicians – who number more than 850 – are acknowledged as leaders in their fields of medicine and surgery. In 2014 UC San Diego had 110 physicians in 40 specialties named “Top Docs” by members of the San Diego County Medical Society as the best physicians in the region.

UC San Diego Health is part of University of California, San Diego Health Sciences. In just over four decades, we have gained international recognition as the one place where discoveries are delivered – bringing breakthroughs from the research laboratory bench to our patients’ bedsides.