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Researchers at the University of California, San Diego School of Medicine report that older women, plucky individuals and those who have suffered a recent major loss are more likely to be compassionate toward strangers than other older adults.

Because compassionate behaviors are associated with better health and well-being as we age, the research findings offer insights into ways to improve the outcomes of individuals whose deficits in compassion put them at risk for becoming lonely and isolated later in life.
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Mutant Protein in Muscle Linked to Neuromuscular Disorder: A new therapeutic target for Kennedy’s disease and a potential treatment

Sometimes known as Kennedy’s disease, spinal and bulbar muscular atrophy (SBMA) is a rare inherited neuromuscular disorder characterized by slowly progressive muscle weakness and atrophy. Researchers have long considered it to be essentially an affliction of primary motor neurons – the cells in the spinal cord and brainstem that control muscle movement. http://health.ucsd.edu/news/releases/Pages/2014-04-16-mutant-protein-linked-to-sbma.aspx
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We have found that the intensity difference between an immune response that stimulates cancer and one that kills it may not be very much,” said principal investigator Ajit Varki, MD, Distinguished Professor of Medicine and Cellular and Molecular Medicine. “This may come as a surprise to researchers exploring two areas typically considered distinct: the role of the immune system in preventing and killing cancers and the role of chronic inflammation in stimulating cancers. As always, it turns out that the immune system is a double-edged sword.”
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The University of California, San Diego Medical Center in Hillcrest has been named one of  “100 Great Hospitals in America” by Becker’s Hospital Review, a publishing group that conducts hospital and healthcare news and analyses, which described the honorees as “some of the most prominent, forward-thinking and focused healthcare facilities in the nation.”

http://health.ucsd.edu/news/releases/Pages/2014-04-02-100-great-hospitals-by-beckers.aspx
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Breaking Bad Mitochondria: Mechanism helps explain persistence of hepatitis C virus

Researchers at the University of California, San Diego School of Medicine have identified a mechanism that explains why people with the hepatitis C virus get liver disease and why the virus is able to persist in the body for so long. http://health.ucsd.edu/news/releases/Pages/2014-04-15-hepatitis-c-and-mitochondria.aspx
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Splice Variants Reveal Connections Among Autism Genes 

A team of researchers from the University of California, San Diego School of Medicine and the Center for Cancer Systems Biology (CCSB) at the Dana-Farber Cancer Institute has uncovered a new aspect of autism, revealing that proteins involved in autism interact with many more partners than previously known. These interactions had not been detected earlier because they involve alternatively spliced forms of autism genes found in the brain. http://health.ucsd.edu/news/releases/Pages/2014-04-11-splice-variants-and-autism.aspx
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Researchers at the University of California, San Diego School of Medicine have found that too little or too much of an enzyme called SRPK1 promotes cancer by disrupting a regulatory event critical for many fundamental cellular processes, including proliferation.
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“A key advantage of this mechanism is that it should be compatible with almost any polymer, even those that are commercially available,” said Mathieu Viger, a post-doctoral fellow in Almutairi’s laboratory and co-lead author of the study. “We’ve observed trapping of water within particles composed of all the biodegradable polymers we’ve so far tested.”
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Introduction

UC San Diego Health System is widely recognized as one of the premier health care systems in the United States. We’re the only academic health system in San Diego. It’s the one place that can offer you and your family medical treatments not available elsewhere in the region. And we don’t just treat disease – we treat you.

UC San Diego Health System was ranked among the nation’s best hospitals in the 2011-2012 issue of U.S. News & World Report, and number 1 in San Diego in the magazine’s first-ever metro rankings in 2011. We were honored as one of the top 15 teaching hospitals in the country by Thomson Reuters in 2010.

Our physicians – who number more than 850 – are acknowledged as leaders in their fields of medicine and surgery. In 2011, nearly 130 of our doctors were named by members of the San Diego County Medical Society as the best physicians in the region.

UC San Diego Health System is part of University of California, San Diego Health Sciences. In just over four decades, we have gained international recognition as the one place where discoveries are delivered – bringing breakthroughs from the research laboratory bench to our patients’ bedsides.