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Rikki Rockett, the drummer for ‘80s band Poison, talks about battling cancer, and how participating in an immunotherapy clinical trial at Moores Cancer Center at UC San Diego Health saved his tongue.
#cancer   #immunotherapy   #health   #medicine   #cancerresearch  
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Join us Wednesday, June 29 as we light up UC San Diego Medical Center in rainbow colors and raise the Pride flag. The lighting ceremony will also honor the lives lost in the recent Orlando tragedy. Raising the Pride flag and lighting our hospital in rainbow colors will serve as a visual reminder that UC San Diego Health continues its support and engagement in the LGBT community. This event will feature local civic and community leaders and a performance by the San Diego Gay Men’s Chorus. For more info and to register for this free event, visit http://health.ucsd.edu/pridelighting
#lgbt #sandiegopride #healthequality
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The San Diego Union-Tribune spotlights top San Diego scientists and their work on major national initiatives — including Cancer Moonshot, Precision Medicine, Microbiome and other cutting-edge research, such as cancer immunotherapy. Features UC San Diego’s Chancellor Pradeep Khosla, Scott Lippman, director, Moores Cancer Center at UC San Diego Health, Rob Knight, Jill Mesirov, Catriona Jamieson and Larry Smarr.
#cancer #microbiome #immunotherapy #ucsdhealth  
San Diego increasingly leading the way in the life sciences
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June is Cancer Immunotherapy Awareness Month! Hear inspiring stories from our patients who had their immune systems trained to fight tumors: go.ucsd.edu/1MuD3k7

Here, two T cells (red) are attacking a cancer cell (white). Credit: National Cancer Institute

#cancer #immunotherapy #immunology #ucsdhealth
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As news and concern about Zika virus spread, UC San Diego School of Medicine and Skaggs School of Pharmacy and Pharmaceutical Sciences have emerged as global research leaders — from establishing a connection to birth defects to identifying and testing a potential vaccine.  Learn more about how our researchers are leading the effort to fight Zika: https://health.ucsd.edu/news/features/Pages/2016-06-09-uc-san-diego-leading-zika-reserach-efforts.aspx
#zikavirus #infectiousdiseases #publichealth #pediatrics #ucsdhealth  
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Body’s Own Gene Editing System Generates Leukemia Stem Cells - Inhibiting the editing enzyme may provide a new therapeutic approach for blood cancers

Cancer stem cells are like zombies — even after a tumor is destroyed, they can keep coming back. These cells have an unlimited capacity to regenerate themselves, making more cancer stem cells and more tumors. Researchers at University of California San Diego School of Medicine have now unraveled how pre-leukemic white blood cell precursors become leukemia stem cells. The study, published June 9 in Cell Stem Cell, used human cells to define the RNA editing enzyme ADAR1’s role in leukemia, and find a way to stop it. Read more here: https://health.ucsd.edu/news/releases/Pages/2016-06-09-gene-editing-system-generates-leukemia-stem-cells.aspx
#stemcells #leukemia #cancer #ucsdhealth  
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so the stem of the cancer cell reforms the RNA to use proteins from the WBC's DNA but then makes cancer cells?
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UC San Diego Health

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Using a database of human tumor genomic data, researchers at the University of California San Diego School of Medicine and Moores Cancer Center discovered that mutation hotspots known as kataegis are a positive marker in breast cancer — patients with kataegis have less invasive tumors and better prognoses. The study also suggests kataegis status could help doctors determine treatment options that might work best for patients with the mutation pattern.
#breastcancer #immunotherapy #precisionmedicine #genetics #diagnostics
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Researchers at University of California San Diego School of Medicine have found that a likely cause of inflammatory myofibroblastic tumors is deficiency in nonsense-mediated RNA decay (NMD), a system cells use to control which genes are activated.
#cancer #pulmonology #molecularbioloty #ucsdhealth  
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Yadira and Heather discuss nanomedicine—using tiny particles to deliver diagnostics and therapeutics—and how this approach helps overcome the biggest challenge to health care today: people. They talk to Adah Almutairi, PhD, associate professor and director of the Center for Excellence in Nanomedicine in the Skaggs School of Pharmacy and Pharmaceutical Sciences at UC San Diego.
#nanomedicine #podcast #nequalsone #ucsdhealth  
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n=5 The NEXT BIG THING may be very, very small by UC San Diego Health
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Researchers at University of California San Diego School of Medicine and University of California, San Francisco School of Medicine report that more than 1 in 3 atrial fibrillation (AF) patients at intermediate to high risk for stroke are treated with aspirin alone, despite previous data showing this therapy to be inferior to blood thinners.
#atrialfibrillation #cardiology #bloodthinners #drugprotocol #ucsdhealth +UCSF School of Medicine 
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Researchers at the University of California San Diego School of Medicine, with colleagues in Pennsylvania and China, report that not only are there distinct differences in key cellular processes and molecular signatures between rheumatoid arthritis (RA) and osteoarthritis (OA) but, more surprisingly, there are joint-specific differences in RA. The findings help explain why drugs treating RA vary in effect and provide a potential new template for precisely targeting treatment for each and every ailing joint.
#arthritis #osteoarthritis #rheumatoidarthritis #ucsdhealth  
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“Diabetes and other metabolic disorders pose an immense, perhaps unprecedented, health threat to virtually everyone,” said Alan Saltiel, PhD, IDMH director and one of the nation’s leaders in the study of metabolic disorders. “Tens of millions of Americans of all ages are already afflicted so the imperative is great to understand better these chronic, life-threatening conditions and find new ways to treat and prevent them.”
#diabetes #metabolicdisorders #obesity #ucsdhealth  
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Introduction

UC San Diego Health is widely recognized as one of the premier health care systems in the United States. We’re the only academic health system in San Diego. It’s the one place that can offer you and your family medical treatments not available elsewhere in the region. And we don’t just treat disease – we treat you.

UC San Diego Health is consistently ranked among the nation’s best hospitals in U.S. News & World Report, and number 1 in San Diego in the magazine’s first-ever metro rankings in 2011. We were honored as one of the top 15 teaching hospitals in the country by Thomson Reuters in 2010.

Our physicians – who number more than 850 – are acknowledged as leaders in their fields of medicine and surgery. In 2014 UC San Diego had 110 physicians in 40 specialties named “Top Docs” by members of the San Diego County Medical Society as the best physicians in the region.

UC San Diego Health is part of University of California, San Diego Health Sciences. In just over four decades, we have gained international recognition as the one place where discoveries are delivered – bringing breakthroughs from the research laboratory bench to our patients’ bedsides.