install, update definitions, temporarily suspend your anti-virus, run quick scan, the run full scan, delete what it recommends you delete, reboot if prompted to.
then download and run superantispyware:
same thing - update it, run a scan, follow instructions. Run another one to make sure it finds nothing else
After that follow up with ccleaner -
in the utility, run the registry cleaner and have it remove unnecessary startup and temp files.