Most people are all too familiar with cannabinoids (the active chemicals in medical marijuana) like Tetrahydrocannabinol (THC) and cannabidiol (CBD). But did you know that there are more than 85 active cannabinoids that have been identified in cannabis? Most medical research focuses on the popular cannabinoids, and the healthy benefits of THC and CBD are well established. But imagine – as more medical research comes out focusing on the many other cannabinoids, we may discover many more incredible properties inherent in the wonderful herb we call cannabis.
Look at Cannabinol or CBN!!! Review the Endocannabinoid System, the bodily process that lets your body put medical marijuana to work. Your brain has two main cannabinoid receptor types – CB1 and CB2. When smoking, eating or otherwise consuming cannabis, those chemicals bond to specific receptors in your body, which is part of why medical marijuana is so safe and natural. While relatively weak, CBN is still very much psychoactive, being a metabolite of THC. While CBN acts mildly on CB1, it has more of an affinity (similar characteristics of compounds that suggest a relationship) for CB2. Because of its relationship with CB2, it works well as an immunosuppressant. Immunosuppression is, as you might guess, when the immune system’s responses (such as inflammation) are shut down. This is an important function when the immune system is overreacting or you need to turn it off. In transplant surgeries, such as bone marrow or liver transplants, you want an immunosuppressant so the body does not reject the transplant. In autoimmune diseases, such as Crohn’s disease or rheumatoid arthritis, the immune system is acting abnormally.
So what this suggests is that CBN could be a useful treatment for things like autoimmune aplastic anemia, celiac disease, or certain surgeries. Other drugs that cause immunosuppression include opioids and cytostatic drugs used in chemotherapy. Perhaps CBN could be a powerful, safer alternative to these kinds of more dangerous drugs.
Furthermore, some early studies of CBN have linked it to stimulated bone growth, making it potentially helpful treating osteoporosis.
A 2008 study found that when applied topically CBN has also been found to be a potent anti-bacterial agent against MRSA, an infection that is difficult to treat.
CBN is also one of the most sedative cannabinoids, so strains higher in CBN work great for insomnia. Steep Hill Halent reported, “The consumption of 2.5mg to 5mg of CBN has the same level of sedation as a mild pharmaceutical sedative, with a relaxed body sensation similar to 5mg to 10mg of diazepam.”
Cannabinol is a byproduct of the degradation of cannabis. In other words, CBN tends to be in higher concentrations in medical marijuana that is old and hasn’t been stored properly. More CBN generally means less THC, so that’s an added benefit for patients who don’t prefer THC. But because of this, it’s unlikely you’ll find strains with high CBN levels at dispensaries, where the cannabis is more fresh. If you want more CBN, you can leave your buds exposed to air for a while or you can wait until more research arrives and you can get concentrated CBN on its own. Whether or not CBN is a panacea, the medical potential is certainly exciting! I've actually found that by allowing my pot to GET old, and then taking the very dry, very very dry, buds, sweet leaf, etc ... and running them through fine grind on my coffee grinder, I have a lovely, fine green flour. With this, I add coconut oil, use a magicalbuttermachine (dot com) [no not a commercial for them, but i do like the machine, it's SUPER easy to use and very inexpensive] ... and make cannabutter. I no longer have insomnia OR restless leg! Plus, I am far less anxious than I've been in decades. Finally got off the benzo's, in fact!
BUT most of what I see online and on youtube is a bunch of trash. Would YOU let your mother ONLY use the stuff they tell you is a "cure" here? Not me! I LOVE my mom. Chemo, radiation, oral meds, even amputation ... AND cannabis? YES! Cannabis helped her sleep, helped her eat and keep the food down, and in general, she simply just FELT better, less anxious, less afraid of dying. She became very calm, very into her own body and, eventually, after fighting for nine years, cancer got her. Maybe in 10 years, or 20 or even 100 ... we humans WILL find a true cure. But until then, do NOT depend upon it to "cure" you of ANYTHING (except insomnia, and that's a certain deal!)
In the meantime, caution is advised. Don't become the victim of a cancer scam. The scamsters are sure to follow this report as night follows day.
T. Reed, Alaska Advocates. Medical Anthropologist/Cannabis Consultant, Homer, Alaska.