This research ("Cloaked DNA nanodevices") is regarding the devices surviving a pilot mission in mice. The news seems very similar to DNA origami news a few weeks before this post, which if you don't remember it was concerning #cockroaches (http://goo.gl/3DEmly) being injected with DNA nanobots, furthermore the cockroach-invading bots had computational capability.

I think the key difference is on this occasion is viral cloaking. We are looking at the DNA nanobots (devices) being cloaked to resemble viruses for the purpose of bypassing the immune system, which perhaps in earlier DNA nanobots for cockroaches was not possible.

Different researchers are mentioned on this occasion. There is no mention of cockroaches this time, so despite both news items having connections to the same organisation (Wyss Harvard, although we must note the cockroach research included or was led by researchers from Bar Ilan University), I think this latest research is slightly different. Please feel free to enlighten me in the comments.

April 2014 was clearly a popular month for news about DNA robots capable of infiltrating living organisms.

Wyss Harvard (Institute for Biologically Inspired Engineering) wrote: "The results pave the way for smart DNA nanorobots that could use logic to diagnose cancer earlier and more accurately than doctors can today; target drugs to tumors, or even manufacture drugs on the spot to cripple cancer, the researchers report in the April 22 online issue of ACS Nano."  http://wyss.harvard.edu/viewpressrelease/150/cloaked-dna-nanodevices-survive-pilot-mission

Vice Motherboard wrote: "However, rather than being flattered by the mimicry, the immune system reacted to the DNA bots in a pretty hostile manner when they were injected into mice. When researchers covered the bots in fluorescent dye and injected them into the rodents' bloodstreams, the bots showed up glowing in their bladders pretty quickly. They were getting caught, filtered, and marked for expulsion." http://motherboard.vice.com/read/dna-nanobots-can-fool-the-immune-system-by-disguising-themselves-as-viruses

Quartz wrote: "They loaded the nanorobots with flourescant dye for tracking and injected them into mice. Nanorobots that fall prey to the immune system’s xenophobia end up in the gut. But, when they scanned the mice injected with cloaked nanorobots, their entire body glowed–evidence that the body was not dispatching them to its waste treatment system." http://qz.com/202221/nanorobots-that-hide-in-your-blood-like-viruses-could-someday-fight-cancer/

Science Daily wrote: "DNA is well known for carrying genetic information, but Shih and other bioengineers are using it instead as a building material. To do this, they use DNA origami -- a method Shih helped extend from 2D to 3D. In this method, scientists take a long strand of DNA and program it to fold into specific shapes, much as a single sheet of paper is folded to create various shapes in the traditional Japanese art." http://www.sciencedaily.com/releases/2014/04/140422100021.htm

TG Daily wrote: "Nature inspired the solution. The scientists designed their nanodevices to mimic a type of virus that protects its genome by enclosing it in a solid protein case, then layering on an oily coating identical to that in membranes that surround living cells. That coating, or envelope, contains a double layer (bilayer) of phospholipid that helps the viruses evade the immune system and delivers them to the cell interior." http://www.tgdaily.com/general-sciences-features/92851-cloaked-dna-nanodevices-survive-pilot-mission

See also: http://www.eurekalert.org/pub_releases/2014-04/wifb-cdn042214.php

#DNAorigami #nanotechnology #nanobots #DNA #dnacomputing  
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