If you have followed previous posts about #minduploading on +Singularity 2045 you'll know I'm dismissive of uploading human brains. The mind-uploading idea is invalid. Yes mind-uploading will likely be possible, but only a very few people will actually do it. Everything you will be able to do in an uploaded state you will be able to do while in a DNA body.

Another problem with the uploading meme is various people mistakenly think mind-uploading is the Singularity. The Singularity is actually an explosion of intelligence. Uploading human brains is very stupid thus, due to the stupidity of it, human-uploading is antithetical to the Singularity.

Mind-uploading creates a false division between machines and biology, which is a division relevant to the 1980s. The future is actually convergence. So-called "machines" will become "biological." The human body is merely a very sophisticated DNA robot.

Ray Kurzweil makes various mistakes regarding his understanding of the Singularity, but I agree very much with his statement of biology now being an information technology. This means the manipulation of #DNA code is essentially identical to manipulation of traditional data, thus advances in biology are now determined by the speed of information technology. Note #bioinformatics progress: http://en.wikipedia.org/wiki/Bioinformatics http://med.stanford.edu/ism/2014/april/diehn.html

We are learning to rewrite the DNA code. We hack viruses to insert new genes (gene therapy). We create insulin via hacked bacteria. Wikipedia wrote on the #biotechnology page: "...in 1978 Genentech developed synthetic humanized insulin by joining its gene with a plasmid vector inserted into the bacterium Escherichia coli." http://en.wikipedia.org/wiki/Biotechnology

Biomolecular engineering is essentially the same as any other engineering. #Biotechnology is technology.

What is possible with biology in 2014? Genetically engineered #StemCells sensitive to light have been transplanted into paralyzed muscles; movement of the muscles is then controlled by light. Scientists have grown living muscle in the lab, which functions identically to the muscles in your body, including self healing! Stem cells from muscle can repair damaged nerves in mice. The CRISPR gene-editing technique can correct faulty genes thereby eliminating disease in mice. Gene therapy can cure disease. Steps forward are being made regarding bacterial or DNA-computing (bio-computing). An artificial-synthetic chromosome based on yeast has been created, with commentators suggesting designer genomes are the next step beyond designer chromosomes. We can create embryos from stem cells in the lab. We can regrow organs from stem cells. Stem cells have been created from adults suing the same cloning technique which created Dolly the sheep. "Biology" is becoming smart. We are also making good progress printing organs via bio-printers!

Nothwestern university stated in April 2014: "A Northwestern synthetic biology team has created a new technology for modifying human cells to create programmable therapeutics that could travel the body and selectively target cancer and other sites of disease."

Subsequent to Craig Venter creating  synthetic life in 2010, the field of #synbio (synthetic biology) has progressed steadily. The BBC wrote in 2010: "Dr Venter likened the advance to making new software for the cell." http://www.bbc.co.uk/news/10132762

In the video trailer for Transcendence we are told mind-uploading is the only route to #immortality despite the fact medicine is progressing at an astonishing rate. We actually have two big companies investing in methods to ensure bio-immortality, or at least to extend our lifespans significantly in the short term. #Google launched their Calico venture in September 2013 and Craig #Venter launched Human Longevity Incorporated (HLI) in March 2014.

The fallacy of mind-uploading is to assume "biological" science is static, thus while scanning brains progresses for uploading, from 2014 to 2034 or beyond, the ability to regrow organs from stem cells or to print organs is oddly ignored. It is assumed "biological" science is static. The uploaders assume medicine will make no progress despite gene-therapy and regenerative medicine already being a reality in 2014. The fact is immortality will be possible via medicine before mind-uploading is possible.

Note how In early April 2014 an organ (thymus) was regenerated for the first time in a living animal (mouse), it was announced: http://medicalxpress.com/news/2014-04-regenerated.html http://goo.gl/Mp1Nmm

Perhaps you will be able to upload a very lossy human brain in the mid 2020s, but that lossy version of you will definitely not be you. In the mid 2020s I would much prefer to be healed via regenerative medicine progress, which everyone with at least half a brain will also prefer.

Despite my criticism of mind-loading there is a valid use for it. I posted, in March 2014, about how scientists plan to upload a bee brain into a bee robot in 2015. A scanned human mind could also provide a template for human-level artificial intelligence. BUT mind-uploading for humans, regarding biology being inferior to machines, it is something that will never really happen.

Before we can fully capture the subtle nuances of the entire human mind we will have almost certainly perfected regenerative medicine, furthermore we will be hacking our DNA to make us smarter and stronger. Cyberspace is great but traditional reality is great too.

I think mind-uploaders are suffering from a type of autism. They have an irrational aversion to biology. I think they are inept at interpersonal interaction thus they want to escape their emotions or bodies. Mind-uploading seems to be a type of escapism. The problem is the uploaders are suffering from a grass greener on the other side syndrome. I am sure they won't actually escape their minds, which is the real thing they are trying to escape, they are not really trying to escape their mortality.

The irony of mind-uploaders is evident in the 2045 Avatar Project (2045 Initiative). They want to enhance intelligence, supposedly, but they prattle on about "spirituality." Spirituality or Gods is nothing to do with intelligence. The way forward is #atheism not spirituality. The 2045 Initiative, which is absolutely nothing to do with Singularity 2045, wrote (bold emphasis added): "The main goals of the 2045 Initiative: the creation and realization of a new strategy for the development of humanity which meets global civilization challenges; the creation of optimale conditions promoting the spiritual enlightenment of humanity; and the realization of a new futuristic reality based on 5 principles: high spirituality, high culture, high ethics, high science and high technologies."

Note how the Dalai Lama supports the 2045 Initiative: http://archive.is/FLUnD

Linked to spiritual nonsense you naturally find satanic hells. The irrationality of religion continues to dominate many aspects of life, often subconsciously, thus many films are merely alternate renditions of the Bible, with heaven and an apocalyptic Judgement Day combined, perhaps with a Christ-like Saviour, or Anti-Christ, thrown in.

Expectation of apocalypse stems largely from the Book of Revelation. It is not actually a problem of technology. It is not a true expectation of advanced technology. It is merely an immemorial problem regarding humans having idiotic ideas. Religion often deals with the irrational notion of humans experiencing a severe judgement or apocalypse.

Humans seemingly enjoy creating false divides, very evident in the Bible.

Let's consider how we can refute the false divide of biology versus machines. Here are two quotes where Ray Kurzweil describes how he thinks biology is now an information technology:

"Health and medicine is now an information technology and is therefore subject to what I call the "law of accelerating returns," which is a doubling of capability (for the same cost) about each year that applies to any information technology." http://edition.cnn.com/2013/12/10/business/ray-kurzweil-future-of-human-life/ http://archive.is/gvbwG

"The most important perspective in my view is that health, medicine, and biology is now an information technology..." http://www.technologyreview.com/view/414240/ray-kurzweil-on-how-to-combat-aging/

Here is a video regarding the mechanical nature of bacteria. Note how nature has created a superbly designed rotary motor, which engineers draw inspiration from to create less accomplished nanobots: Building Medical Robots, Bacteria sized: Bradley Nelson at TEDxZurich.

Here are some "mechanical gears" in nature: Mechanical gears in jumping insects.

Whether life in the future is based on DNA, graphene, silicon, light, neon, or something else, the life will be biological. The cells of AI will in essence be identical to the cells of DNA humans. The false division between humans and AI is great for a scary film; but the fiction, similar to God, does not represent reality. There seems to be a 1980s wrong-headed idea that "machines" will always be clunking inhuman  contraptions.

Some people think mind-uploading (backing-up your brain) will be valid to protect yourself from accidents. If your body is totally destroyed it is assumed you can download a backed-up version of yourself into a new body. I don't think backing-up your brain will ever be valid. Catastrophic accidents, which completely destroy your body beyond repair, represent a very rare risk thus people will not be concerned about this rare risk. Technology will soon make our bodies much stronger via DNA manipulation, furthermore technology will make our world much safer, thus rare total body destruction will become much rarer. I think at the stage when backing up your brain is possible, technology will also have reduced catastrophic incidents to almost zero.

Tardigrades (water bears) are extremophiles able to withstand physical extremes. Human DNA could be engineered beyond mere natural extremes. It will also be easy to augment DNA with very unobtrusive nanotech armor. I am sure technology in the future will easily protect DNA from any accident or incident. We will progress very far beyond crash-helmets, airbags, or intelligent auto-pilots. In the future I am sure DNA humans will easily be able to withstand any explosion or other catastrophe. The best thing is, such disasters simply will not happen in the future.

We should give intelligence more credit.

The film #transcendence could be very entertaining despite my criticism. Just remember it is fiction of a type VERY unlikely to ever become fact.

If you notice any typos in this first draft let me know in the comments, I will be editing this over the next couple of days months.
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