Business Week: "In the natural world, just two chemical base pairs, known simply as A-T and C-G, constitute the building blocks of DNA in all life forms. Research published today in the scientific journal Nature describes the creation of a cell that contains a man-made base pair, dubbed d5SICS-dNAM."

Daily Mail: "...a replicating ‘alien’ life-form has been made by scientists who introduced DNA molecules not found in nature to a common bacterium."

RT: "American scientists have for the first time ever made it possible for an organism to survive with artificial DNA, making it more likely new medicines can be developed, while raising ethical concerns among some advocates."

Scientific American: "The first challenge to creating this alien life was to get cells to accept the foreign bases needed to maintain the molecule in DNA through repeated rounds of cell division, during which DNA is copied. The team engineered the bacterium Escherichia coli to express a gene from a diatom — a single-celled alga — encoding a protein that allowed the molecules to pass through the bacterium's membrane."

Discover Magazine: "But could we create an entirely new organism with unnatural DNA? At the moment, no, says Romesberg."

CNET: "Not only can these artificially created organisms be used to generate new medicines as base pairs are the source of proteins, but it also has applications in understanding life itself, from the sustainability of alien forms that differ from our own genetic makeup to the secrets of Earth's living organism construction."

NY Times: "In effect, the bacteria have a genetic code of six letters rather than four, perhaps allowing them to make novel proteins."

The Guardian: "Researchers say the work challenges the dogma that the molecules of life making up DNA are "special". Organisms that carry the beefed-up DNA code could be designed to churn out new forms of drugs that otherwise could not be made, they have claimed."

#DNA #synbio #biotech #bacteria #ecoli  
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