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Roderick Omari
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Roderick Omari

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Gentlemen, tech doesn't have to be boring. Make it yours...
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+Roderick Omari thanks for the info. 
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Wow...These advancements should lead to cheaper drugs, and new treatments amongst other things.

h/t to +Marla Caldwell  
 
SciTech #ScienceSunday Digest - 21/2015.
Permalink here: http://www.scitechdigest.net/2015/05/yeast-opiate-production-crispr-gmo.html

Yeast opiate production, CRISPR GMO killswitch, Optical computation, Continuous roll graphene, Cell periodic table, Immune evading implants, Wearable muscle sensor, Molecular pumps, Learning robots, Laser scanner. 

1. Engineered Yeast for Opiate Production
After a number of years of effort by multiple groups the final enzymatic synthetic step in the pathway for opiate production (morphine, etc) has been completed and it is now possible to create strains of yeast that produce opiate drugs as part of normal metabolism http://www.nature.com/news/drugs-regulate-home-brew-opiates-1.17563. With such a strain and basic fermentation skills morphine-producing yeast could be grown in a home-brew beer kit, but the original development was intended for cheaper, simpler, production of opiates. I disagree strongly with the alarmist commentary and propaganda around this, including this quote from the linked article “All told, decentralized and localized production would almost certainly reduce the cost and increase the availability of illegal opiates — substantially worsening a worldwide problem.” which I consider myopic; I believe this would substantially improve a worldwide problem. 

2. CRISPR-Based GMO Kill-Switch
CRISPR has now been employed in a novel way to trigger the removal and destruction of modified genes from genetically modified organisms and leaving the original genes intact http://www.theverge.com/2015/5/19/8625623/gmo-crispr-kill-switch-self-destructing-dna. It seems the system can kill the cells directly, inactivate or delete just the modified or introduced genes, or do both. Triggers for activating the system could include light levels, the presence or absence of a particular molecule - useful for controlling crops for example - and others. This seems to be similar in application to Terminator gene technology that was developed to limit the spread of GMO crops by preventing the growth of new seed, but in this case you would still get seed that could only be grow in desired areas. 

3. Optical Computing Developments
We had a trio of advances in optical computing this week. First, the smallest-ever silicon photonic beam-splitter has been demonstrated, designed by novel algorithms, measuring just 2.4 microns on a side, and promising faster on-chip communication and processing http://unews.utah.edu/news_releases/silicon-photonics/. IBM announces new CMOS integrated silicon nanophotonics technology and new chips designed to work alongside electrical chips while transferring data at 100 Gbps (full HD movie in 2 seconds), first application in high end servers and data centers http://www-03.ibm.com/press/us/en/pressrelease/46839.wss. Layers of 2D graphene and boron nitride allow controlled propagation of confined light pulses (within the layered sheets) when a voltage is applied to the graphene http://newsoffice.mit.edu/2015/tuning-light-waves-with-2-d-materials-0520

4. Continuous Roll Production of Graphene
A new continuous roll-to-roll production method for manufacturing large sheets of graphene and possibly other 2D materials https://newsoffice.mit.edu/2015/manufacture-continuous-rolls-graphene-0521. At a rate of 2.5cm per minute the sheets are uniform and high-quality single-layer graphene; faster rates, up to 20x, still produce coated sheets but these are lower-quality with defects. While the process doesn’t yet produce sheets equal to the best batch-processing methods, different applications will have different quality requirements. Further improvements should result in improved quality and production speed. In related news a new 60% - 70% graphene ink formulation allows 3D printing of robust structures that retain many of graphene’s useful properties and used these as custom tissue scaffolds seeded with stem cells http://www.mccormick.northwestern.edu/news/articles/2015/05/printing-3D-graphene-structures-for-tissue-engineering.html

5. Towards a Periodic Table of Cells
New microfluidics technology can efficiently isolate single cells from a sample for analysis and when combined with new technology for single cell genomic analysis via cataloguing the mRNA expression profile of single cells is leading to an explosion in data and new knowledeg about different cell types in different tissues http://www.technologyreview.com/news/537416/single-cells-analyzed-at-unprecedented-scale/. This has resulted in identifying cells never seen before and recent studies such as a survey of 466 individual brain cells as a step towards a full cellular brain atlas, and mapping thousands of cells from a mouse brain to identify 47 different types. This is inching towards a periodic table of cells and a complete cellular map for the human body and their functions. In related news microfluidic techniques can now squeeze (immune) cells and force the introduction of desired antigens into them in order to create better and more effective vaccines out of the patient’s own cells http://newsoffice.mit.edu/2015/cell-squeezing-device-vaccines-0522

6. Better Implants that Evade the Immune System
New studies indicate that the geometry of implanted devices significantly affects how the body and immune system will tolerate their presence http://newsoffice.mit.edu/2015/designing-better-medical-implants-0518. While the material is important their results suggest that larger, spherical devices are better able to maintain their function and avoid the buildup of scar tissue. 0.5mm spheres loaded with pancreatic islet cells to treat diabetic mice failed within a month, whereas 1.5mm spheres continued to function past six months. Similar performance improvement were observed in many materials and also in primates. This is a very interesting platform for introducing novel living biosensors and living drug factories into people. 

7. Wearable Muscle Sensors with MyoWare
A new muscle sensor designed to be temporarily stuck on to your skin above the muscle group that you want to use can be used to trigger commands in various electronic devices and is currently available via kickstarter http://www.coolwearable.com/myoware-muscle/. This is related to the Myo gesture control armband that I’ve been keen to try out and I’d be tempted to back the kickstarter myself if the device came with bluetooth and could interface with my phone. I’m looking forward to further miniaturisation that allows these sensors and their wireless transmitters to be implanted and to take higher resolution readings. 

8. Designing a New Molecular Pump
The first entirely artificial molecular pump has been designed in which molecules pump other molecules http://www.northwestern.edu/newscenter/stories/2015/05/nature-inspires-first-artificial-molecular-pump-.html. The pump works via simple chemical reactions, driving molecules step by step up higher energy states and away from a natural equilibrium. The basic architecture involves a ring-shaped molecule that moves along a molecular thread or chain, storing energy as it does so by moving multiple rings towards one end. An interesting research novelty for now the ultimate goal is to have these little molecular machines power nanoscale devices, muscles, and perhaps perform computational operations. 

9. Learning Robots & Machines with Complex Goals
New deep learning algorithms enable some robots to learn new tasks via trial and error without pre-programmed details about the environment http://newscenter.berkeley.edu/2015/05/21/deep-learning-robot-masters-skills-via-trial-and-error/. A variety of tasks were successfully tested including putting a hanger on a rack, assembling a toy, screwing a cap on a bottle, and others, with learning times averaging 10 minutes to 3 hours depending on the level of complexity. In related news a reinforcement learning approach has demonstrated game-playing software that is capable of creating a hierarchy of goals while working towards a delayed reward http://nextbigfuture.com/2015/05/keen-software-house-makes-ai-that-can.html

10. Non-Mechanical Laser Scanner
DARPA has demonstrated its SWEEPER technology for enabling drastically improved LIDAR applications http://www.darpa.mil/NewsEvents/Releases/2015/05/21.aspx. Unlike conventional LIDAR devices SWEEPER does not require mechanical components and instead exploits silicon-based on-chip optical phased array technology that can sweep a laser beam back and forth 100,000 times per second. This is expected to enable LIDAR systems that are drastically miniaturised and extremely low-cost. Given LIDAR systems in autonomous vehicles are one of the most expensive components in an autonomous vehicle the benefits for a diverse array of applications are immense. A future version of Project Tango could even have one of these devices. 

Archive: http://www.scitechdigest.net/2015/05/yeast-opiate-production-crispr-gmo.html 
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Cheap drugs... Pahhhahahaha that'll be the day. 👍😉
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Roderick Omari

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Confirmed

At the federal level only, largely due to increased oil and gas, production, fossil fuel production and exploration subsidies have grown in value by 45 percent since President Obama took office in 2009 from $12.7 billion to a current total of $18.5 billion. 

Repeated attempts by the Administration to reduce subsidies have failed at least in part because of the cozy relationship between Congress and the fossil fuel industry. In 2011-12, oil, gas, and coal companies spent $329 million in campaign finance contributions and lobbying expenditures and received $33 billion in federal subsidies over the same two years – a more than 10,000 percent return on investment. 😦

Full report  
http://priceofoil.org/content/uploads/2014/07/OCI_US_FF_Subsidies_Final_Screen.pdf
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Yup. If the government only spent that much money on researching and promoting the development and use of clean, renewable energy, we'd all be in a better place.
Of course, politicians don't really care about improving the conditions of this world... It's all about the money.
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Roderick Omari

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WANT

The world’s first unrestricted, high resolution, write-virtually-anywhere mobile input device.

Phree™ will easily connect to all your devices: phone, tablet, laptop, TV…anything with a Bluetooth connection. And Phree is compatible with software and apps like Office, OneNote, EverNote, Acrobat, Google Handwriting Keyboard, Viber and more.

even functions as a headset and has an integrated screen for brief texts. When you get one, just write back and send.



https://www.kickstarter.com/projects/1958554063/phree-make-the-world-your-paper
OTM Technologies Ltd. is raising funds for Phree - Make the world your paper on Kickstarter! The world’s first unrestricted, high resolution, write-virtually-anywhere mobile input device.
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#GadgetQueen  needs to see this in person
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Roderick Omari

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Eli Fennell originally shared to Technology:
 
Apple Watch Shipment Predictions Cut in Half

Based on demand for Apple Watch's Taptic Engine, KGI research has revised their initial estimates of 20-30 million Apple Watches shipped in 2015 to under 15mn, and notes that demand for the product appears to be slowing, with the larger screen version easily outperforming the smaller version.

This would still be an impressive number for the category, but might suggest limited demand outside of Apple 'Super Fans'. It may even be a sign that wearables have yet to find their 'Killer Use' for consumers, who are holding back on these expensive smartphone accessories as a result.

A slow start won't necessarily doom the smartwatch, but may suggest the need for a broader wearables category. Perhaps watches alone won't be the new smartphones.

#AppleWatch #Wearables
A new KGI research note predicts that production of the Apple Watch's Taptic Engine component will begin to improve later this month, but slow demand has led to a downward revision of estimated shi...
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+LadyDi M Cool. Looking forward to it 👍
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I know every day is full of regret. 
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One of the best features on Android that not many of us use. 
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IFTTT gives you creative control over the products and apps you love.

I don't know if anyone I follow actually actually uses IFTTT (If This Then That). I watched a thorough tutorial this morning, by +David A. Cox

Link to David's video
https://www.youtube.com/watch?v=CEAVFU3ELcI&feature=share

If This Then That (also know as IFTTT) is a way to easily automate tasks in your life. It can be automatically saving photos that you're tagged in on Facebook to Dropbox, a security alert if your family members calls for emergency services, or even if you want your coffee pot to automatically turn on when you wake up in the morning. IFTT's customizations are practically endless. In this class which was recorded with a live audience will show you how to create automated tasks, offer advice on what gadgets you might want to think about purchasing in order to make that happen, and of course we'll share with you our favorite IFTT recipes.
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My number one reason I started using it is the ability for me to have my phone put on silent mode or taken off silent mode based off location or WiFi network I connect to.

It has a ton of uses though. 
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I've never been afraid of big moments. I get butterflies. I get nervous and anxious, but I think those are all good signs that I'm ready for the moment. -Stephen Curry #MVP  
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Dude is killing the Rockets lol
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Next time I'm out that way, you better believe I'm going to try these fine establishments. Just look at the food 😍

h/t to +Gus Alexandropoulos 
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thats soul food-  we eat that 4-5 times a week
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+Earl Matthews is on point 😂😂😂
 
How is it so easy for other countries to say. "Ok, chaps. Lets be adults and vote with clear heads about this." and when the United States tries its "Jesus, Cowboys, Rapture, Jesus, Morality, Terrorism"
Living in the United States is like being tied to a crazy person that is constantly cursing and shitting himself.
We're the same country that though that our own military was invading Texas. Which makes about as much sense as my car invading my garage.  
Votes are being counted Saturday in Ireland's historic referendum on same-sex marriage, with early indications suggesting the "yes" vote will win.
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+Jeremy Collins It sure is, man. We can do so much better as a country. 
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Shane Menshik originally shared to Android:
 
For those wondering how to setup nicknames for your contacts when using voice actions in google now.

https://support.google.com/websearch/answer/4584610?p=contact_relationships&rd=1

Example:

OK Google... Phyllis is my mom
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Roderick's Collections
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Map of the places this user has livedMap of the places this user has livedMap of the places this user has lived
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San Antonio - Sacramento - Seattle - NYC - San Juan PR - San Antonio
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I have lived a lot of places and visited even more. I've truly been inspired by the people I have befriended and the things that I see people of the world share in common. The best part is I'm just getting started...
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OmariWorld
Their Pho hits the spot when I'm in need. Every once and a while I have a serious craving for Pho and this is usually where I decide to spend my money.
Public - 2 months ago
reviewed 2 months ago
Just terrible. The service was good but the food was insulting...
Public - 3 months ago
reviewed 3 months ago
This place is really convenient. They have a drive through and there's always enough staff to meet the demand. Oh, and the donuts are pretty good.
Public - 3 months ago
reviewed 3 months ago
Friendly staff, nice cafe, and super fast WiFi. I don't know why they don't advertise that.
Public - 3 months ago
reviewed 3 months ago
10 reviews
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Long lines, empty shelves, most of the cashiers are decent but they have a couple that don't even greet you, and it's a small store with a very limited selection. There really isn't much that can be done, other than closing it down. I'd recommend shopping at another safeway. This is the worst one I've ever seen.
Public - 3 months ago
reviewed 3 months ago
Cold fries... If you complain about getting cold fries the manager will give you a bad time. Also, they won't give you a refund if they give you cold food. They need a change in management.
Public - 3 months ago
reviewed 3 months ago
This is my favorite Costco! I can't believe we have a Costco in the city. It just sounds like it would be a total nightmare but it works. 3 level parking FOR FREE! It's even easier to get in and out of than the one in South San Francisco and it's close to the freeway.
Public - a year ago
reviewed a year ago