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Ralf Haring
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"The social wasp Polybia paulista protects itself against predators by producing venom known to contain a powerful cancer-fighting ingredient. A Biophysical Journal study published September 1 reveals exactly how the venom's toxin—called MP1 (Polybia-MP1)—selectively kills cancer cells without harming normal cells. MP1 interacts with lipids that are abnormally distributed on the surface of cancer cells, creating gaping holes that allow molecules crucial for cell function to leak out."
 
The social wasp Polybia paulista protects itself against predators by producing venom known to contain a powerful cancer-fighting ingredient. A Biophysical Journal study published September 1 reveals exactly how the venom's toxin—called MP1 (Polybia-MP1)—selectively kills cancer cells without harming normal cells. MP1 interacts with lipids that are abnormally distributed on the surface of cancer cells, creating gaping holes that allow molecules c...
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iirc my copy of CIV came with the full game and steam installer, the default install process still downloaded+installed the whole game via steam.
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"If you believe the data, then one question remains. Why have the more pessimistic predictions not come to pass? One incontrovertible reason is that — contrary to the justifiable fears of a decade ago — people will still pay for creative works. The Napsterization of culture turned out to be less of a threat to prices than it initially appeared. Consumers spend less for recorded music, but more for live. Most American households pay for television content, a revenue stream that for all practical purposes didn’t exist 40 years ago. Average movie-­ticket prices continue to rise. For interesting reasons, book piracy hasn’t taken off the way it did with music. And a whole new creative industry — video games — has arisen to become as lucrative as Hollywood. American households in 2013 spent 4.9 percent of their income on entertainment, the exact same percentage they spent in 2000."

"At the same time, there are now more ways to buy creative work, thanks to the proliferation of content-­delivery platforms. Practically every device consumers own is tempting them at all hours with new films or songs or shows to purchase. Virtually no one bought anything on their computer just 20 years ago; the idea of using a phone to buy and read a 700-page book about a blind girl in occupied France would have sounded like a joke even 10 years ago. But today, our phones sell us every form of media imaginable; our TVs charge us for video-­on-­demand products; our car stereos urge us to sign up for SiriusXM."

"And just as there are more avenues for consumers to pay for creative work, there are more ways to be compensated for making that work. Think of that signature flourish of 2000s-­era television artistry: the exquisitely curated (and usually obscure) song that signals the transition from final shot to the rolling credits. Having a track featured during the credits of ‘‘Girls’’ or ‘‘Breaking Bad’’ or ‘‘True Blood’’ can be worth hundreds of thousands of dollars to a songwriter. (Before that point, the idea of licensing a popular song for the credits of a television series was almost unheard-­of.) Video-­game budgets pay for actors, composers, writers and song licenses. There are YouTube videos generating ad revenue and Amazon Kindle Singles earning royalties, not to mention those emerging studios (like Netflix and Yahoo) that are spending significant dollars on high-­quality video. Filmmakers alone have raised more than $290 million on Kickstarter for their creations. Musicians are supplementing their income with instrument lessons on YouTube. All of these outlets are potential sources of revenue for the creative class, and all of them are creatures of the post-­Napster era. The Future of Music Coalition recently published a list of all the revenue streams available to musicians today, everything from sheet-­music sales at concerts to vinyl-­album sales. They came up with 46 distinct sources, 13 of which — including YouTube partner revenue and ringtone royalties — were nonexistent 15 years ago, and six of which, including film and television licensing, have greatly expanded in the digital age."
In the digital economy, it was supposed to be impossible to make money by making art. Instead, creative careers are thriving — but in complicated and unexpected ways.
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True... they're just able to avoid personal contact when they do it now.  :-/
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Among legendary Irishmen stands tall Michael Malloy who refused to die by drinking himself to death even though his friends, who stood to profit handsomely from his death, gave him all sorts of nasty stuff to drink.  Finally, said friends gave up and decided to kill him through inhalation of nasty stuff instead.
This is the story of Michael Malloy, a Prohibition-era drunkard best known for his unpaid bar tabs and being (almost) impossible to kill. Here, Elemental's Deborah Blum recounts how Malloy (who would come to be known as "Mike the Durable," and "Iron Mike") survived multiple attempts on his life — and some of the science behind the murderous method that finally did him in. This post by originally appeared on Wired Science Blogs' . Blum is a Pulitz...
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I always have time for any of Scott's movies and enjoyed the hot mess that was the first one to an unreasonable degree (because of just how much of a mess it was). There's really no way a sequel could live up to my expectations, though. It was like capturing lighting in a bottle, except it was super crappy lightning in amazing Murano glass.
While talking to Empire about his new film, The Martian, director Ridley Scott mentioned after shooting was complete, he was on a time-crunch because “I was starting to was starting to look for locations for my next movie, which is Prometheus 2.” That sure looks like confirmation that he’s actually making the sequel to his... Read more »
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"Self-interested business owners successfully petitioned the Columbia, Missouri, city council to create a local Community Improvement District, which would have the authority to impose a half-cent sales tax increase with voter approval. However, the district lines were drawn in a manner that attempted to avoid containing any eligible voters, meaning that property-owners themselves would get to decide on the sales tax increase as a way to avoid further property taxes to pay for improvements. Unfortunately for them, things didn't exactly go according to plan. It soon became known that a single voter, University of Missouri student Jen Henderson, was registered to vote in the new CID. That means that she alone will get to decide whether or not to approve the sales tax increase."
 
Map of the new Community Improvement District in Columbia, Missouri Normally gerrymandering in a medium-sized town that ...
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iPad only ... sigh
It has been talked about for so long. And now it is here. Electricomics, the real life emergence of a new kind of digital comic book storytelling experience, ripped from the fiction of Alan Moore and Mitch Jenkins‘ The Show film projects. And with an all-star cast of comic book creators to boot. You can... Read more »
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The iron curtain persists.
Two islands in the Bering Straits are barely two miles apart but divided by the US-Russian border. Humphrey Hawksley visited one and looked across.
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As someone on Twitter said: it would be cheaper to just build a wall around Scott Walker.
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"I recently read one of those funny-and-horrifying articles where a woman on Tinder set a rule that any man contacting her had to name five books by female authors he’d read, and details the inevitable massive fail that ensued.  And you probably know how the knee-jerk reaction to such an article goes.  Educated male smugness followed by, wait, can I definitely do that?"
I recently read one of those funny-and-horrifying articles where a woman on Tinder set a rule that any man contacting her had to name five books by female authors he'd read, and details the inevita...
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Ooh what a neat idea..

"The Handmaid's Tale" by Margaret Atwood

"A Wrinkle in Time" by Madeline L'engle

"When She Woke" by Hillary Jordan

"We Have Always Lived in the Castle" by Shirley Jackson

"We Need to Talk About Kevin" by Lionel Shriver

So many more!
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"In the data dump of Ashley Madison’s internal emails, I found ample evidence that the company was actively paying people to create fake profiles. Sometimes they outsourced to companies who build fake profiles, like the ones Caitlin Dewey wrote about this week in the Washington Post. But many appear to have been generated by people working for Ashley Madison. The company even had a shorthand for these fake profiles—“angels.”"
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"These emails make clear that the company engaged in a deliberate, elaborate, multi-year campaign to create fake profiles for audiences all over the world. And it was something that many senior employees know about. Indeed, earlier this week, the Daily Dot’s Dell Cameron reported that former Ashley Madison spokesperson Louise Van der Velde threatened to expose the “false data” on the site, writing in an email to the company’s general counsel that there are “really no women.” In a possibly deliberate irony, Ashley Madison’s logo is nearly identical to the poster for the remake of The Stepford Wives, a movie about a gated community where all the men replace their wives with beautiful, cheerful robots."
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"Instead of looking at Ashley Madison as a dating site, I think it’s more accurate to call it an anti-community—a hugely popular social site where it’s impossible to be social, because the men can’t talk to each other, most of the women are fake, and the only interaction available is with credit card payments. It is one of the purest representations of dystopia I’ve ever seen."
 
Yes, this is a sad thing. BUT what's interesting is not all the men on the site were after women. There were men seeking men too right? 
Now we know that almost none of the woman in the Ashley Madison database ever used the site. The question is, was this a deliberate fraud? Or was it just a dating site gone wrong?
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That site is not only one , there is a few that is under the guard of Facebook since the board members are sitting in the board of ' DAITING & Gentleman club sites ', they cashing in huge amounts of money with fake scam accounts. There is no one controlling , fully legal to scam people out of money.
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"And so HBO went to the company that set new records for online streaming during the 2014 World Cup, a strange tech startup hidden inside of a sports league, Major League Baseball Advanced Media, or BAM for short. BAM began as the in-house IT department for the league’s 30 teams, a small handful of employees originally tasked with building websites for teams and clubs. But over the last 15 years, BAM has emerged as the most talented and reliable name in streaming video, a skill set suddenly in very high demand."
 
It was the first week of April, 2015, and New York’s Chelsea Market, typically packed with hordes of noisy tourists, was quiet. It was close to midnight, but five stories above, things were tense....
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Clean Up Google Music [De-Instant Mix/Radio]
chrome.google.com

Google Music includes auto-generated Instant Mix/Radio Station playlists that cannot be removed.

De-Radio Station Google Music
chrome.google.com

Google Music includes auto-generated Radio Station playlists that cannot be removed.

G+ Hide Posts
chrome.google.com

Allows hiding posts on Google+ without permanently muting them and removing them from all future search results.

G+ Show All Pages
chrome.google.com

The G+ tab strip contains a Pages button. Only three of a user's pages are accessible when you hover over this button.

De-Instant Mix Google Music
chrome.google.com

Google Music includes auto-generated Instant Mix playlists that cannot be removed.

G+ Show Saved Searches
chrome.google.com

The G+ main page would be slightly more useful if the saved searches were available right above the trending topics.

G+ Lightbox - Hide Maximize Icon
chrome.google.com

The G+ lightbox contains a maximize icon that obscures the image and never completely fades out.