Profile cover photo
Profile photo
PhalanxBio, Inc.
10 followers
10 followers
About
Posts

Post has attachment
This month’s Research Highlight focuses on triple negative breast cancer (TNBC) and how mesenchymal stem cells in the tumor microenvironment can influence therapeutic responses. Read more: https://goo.gl/xWRfhZ #research #TNBC #stemcells
Add a comment...

Post has attachment
This month we’re excited to feature an article from the lab of Hafiz Ahmed and others at the University of Maryland, School of Medicine. The article was published 15 July 2017 in the journal Oncotarget and includes gene expression data generated by the Phalanx Biotech service lab using our Human Whole Genome OneArray Microarray platform.
This study focuses on treatment of PC-3 prostate cancer cells with tunicamycin, a natural antibiotic known to induce ER stress. ER stress occurs when there is an imbalance between the demand for protein synthesis and the ability of the ER to carry out proper protein maturation and transport. The unfolded protein response is the cell’s natural response to alleviating ER stress. ER stress is also linked to cell death, as it can initiate both autophagy and apoptosis. This study ultimately reveals a signaling mechanism by which tunicamycin causes ER stress and reactive oxygen species (ROS)-induced apoptosis. Read more:https://goo.gl/CiP9p6 #microarray #onearray #Phalanxbio
Add a comment...

Post has attachment
This month's Research Highlight features an article from the lab of Ku-Chung Chen and others at Taipei Medical University in Taiwan. The article was published 7 April 2017 in the journal Scientific Reports and includes miRNA expression data generated by the Phalanx Biotech service lab using our Human miRNA OneArray Microarray platform. https://goo.gl/2jYEe1
Add a comment...

Post has attachment
This blog article explores the rising popularity of Whole Exome Sequencing. We also share aspects that make Whole Exome Sequencing advantageous over Whole Genome Sequencing.
https://goo.gl/bhzBTg

#lifescience #news
Add a comment...

Post has attachment
Read our blog about, "Do I Need to Validate My RNA-Seq Results With qPCR?" Here we give some guidance on when is it appropriate to validate RNA-Seq results with qPCR, and when is it may be unnecessary. Read more: https://goo.gl/TdX3YB #research #biology #qPCR
Add a comment...

Post has attachment
MicroRNA Dysregulation in EGFR Exon 19 Deletion Lung Cancer
This month’s study focuses on microRNA dysregulation in EGFR Exon 19 Deletion, and its role in lung cancer, using the Human OneArray® MicroRNA, conducted at the Phalanx Biotech Lab. We feature an article from Lixia Ju and others of Tongji University Medical School Cancer Institute in Shanghai, China. The article was published 11 May 2017 in the Journal of Cancer and includes miRNA expression data generated by Phalanx Biotech’s service lab on our own Human miRNA OneArray® Microarray platform.
In the era of precision medicine, patient survival can increase by designing therapies specific to cancer subtypes. Lung cancer is a great example, as different somatic mutations in the EGFR gene are connected to differential sensitivity to the leading class of drugs. The authors seek to understand how the deletion of EGFR exon 19 affects the expression of miRNAs.
Read more at https://goo.gl/xQPCyd #lifescience #genomics #onearray
Add a comment...

Post has attachment
Add a comment...

Post has attachment
Add a comment...

Post has attachment
Read our new research highlight, a "Study of Gene Expression Changes in Astrocytes Using Agilent Gene Expression Microarray at the Phalanx Biotech Service Lab."

This paper takes a systems biology approach to understanding how astrocytes respond to amphetamines. This study, from the lab of Maria Cecilia Marcondes of the San Diego Biomedical Research Institute in San Diego, CA, includes Agilent gene expression microarray data generated by Phalanx Biotech. The article was published 9 Mar 2017 in the Journal of Neuroinflammation.

The authors focused on astrocytes because studies of the brains of meth users found that astrogliosis was a hallmark of meth exposure. Considering the neurological conditions accompanied by meth abuse, the authors sought to identify the molecular and cellular pathways occurring within astrocytes that may contribute to the neuropathology of meth abuse. Read more: https://goo.gl/3PeogM

#genomics #lifescience #microarray #genes

Add a comment...

Post has attachment
It's really about #bioinformatics! Our #bigdata team is helping make breakthrough discoveries in #drugdevelopment. https://goo.gl/wnUWLD
Add a comment...
Wait while more posts are being loaded