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Oskar Haeger
Lives in Borås
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Oskar Haeger

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Some more #airporn for you. Swedish fighter Viggen in a practice flight for a show.
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Jan Persson's profile photo
 
F***ing music! :-(
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Oskar Haeger

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Almost ran over a badger on my way to work. Fearless little f*cker just took a stroll right out in front of my car.
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I'm glad no badgers nor humans got hurt. 
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But pretty soon....
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High fat diets as a risk factor for cancer? But #lchf and #lchfdiet ?
Fat is bad again then. Good to know.
 
The Hallmarks of Cancer: 8 - Tumor-Promoting Inflammation

After a too-long hiatus, here is my eighth article in this series :) The Hallmarks of Cancer are ten anti-cancer defense mechanisms that are hardwired into our cells, that must be breached by a cell on the path towards cancer. The Eighth Hallmark of Cancer is defined as "Tumor-Promoting Inflammation". All seven previous Hallmark articles can be found here: http://goo.gl/IDGfLp

As always, because this is such a complex topic, I don't want to skip details at the cost of avoiding TL;DR. So I've written a far more detailed explanation (complete with my own diagrams!) that is easier to follow on +Scientific American, and I highly recommend you check it out here: http://goo.gl/ThMpl9. In this article, I explain the complex relationship between inflammation and cancer, and how our own immune system can 'turn traitor' and promote cancer development.

✤ Within the last few years, we have obtained clear evidence that inflammation plays a critical role in cancer development, and we are just beginning to understand the molecular mechanisms of how this happens. Chronic infections, obesity, smoking, alcohol consumption, environmental pollutants and high fat diets are now recognized as major risk factors for most common types of cancer; and, importantly, all these risk factors are linked to cancer through inflammation. 

✤ Inflammation is how tissues and cells respond to injury. If the inflammation causing agent persists for a prolonged period of time, the body’s response to it becomes a chronic inflammation. Chronic inflammation increases cancer risk. 

✤ An extremely graphic yet apt way of describing a tumor is as “a wound that doesn’t heal”. Indeed, there are many similarities between a cancerous tumor and the process of wound healing. Both involve the growth, survival, and migration of cells; both require the growth of new blood vessels; importantly, all these processes are controlled by growth factors and signalling molecules. Just as the immune cells gather near a site of injury to secrete growth factors to begin tissue repair, tumors can also surround themselves with immune cells that secrete these same growth factors to promote their uncontrolled cell growth. 

✤ Tumor Associated Macrophages (TAMs), a 'corrupted' type of immune cell support tumors in four different ways; by providing growth factors, helping to develop a blood supply to the tumor, promoting metastasis and suppressing the tumor-killing abilities of the immune system. Essentially, TAMs help the tumor overcome the barriers represented by the anti-cancer defence mechanisms that consist the Hallmarks. 

✤ The existence of both tumor-promoting and tumor-killing immune cells at first seems counter-intuitive. The immune cells specializing in wound cleaning and clearing up dead cells are recruited and subverted by tumor cells to support tumor growth and progression. Shifting the balance from tumor-promoting to tumor-killing immune involvement therefore represents an attractive and powerful possibility for future therapy. 

#ScienceSunday   #ScienceEveryday   #HallmarksOfCancer  
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Oskar Haeger

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Yeah, got reminded of this game too. I've spent far too much money on this one too. I think it was on laserdisc game in arcade near where I lived. Unlike Dragons Lair I actually finished this one.
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Stuck in traffic!
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ew
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In his circles
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Dear +Google+ gods, may we please have a function to expand all comments in a thread? It's quite tedious to click "read more" on each and every one of them. Sometimes comments are just that darn interesting.
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Morning run during easter. Very nice.
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It starts small....
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Blir lite förvirrad här i bildsekvensen. Oskar religiös...? Liten kyrka av trä?? Trävägg med eld??? och resterna av en brasa. Tuttade du fyr på kapellet? :-D 
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Our tiny chapel in easter.
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I am a secular humanist, or atheist if you will, that tries to have a science based approach to life. I enjoy having my beliefs challenged. Provide facts and research and let's learn together.That also means that I will challenge your beliefs. This can be uncomfortable. Don't be offended, reply in kind. Just be respectful, and so will I. I circle engagers, so if you interact with me I'll most likely will circle you.
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Borås
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Trevligt snabbt och bra bemötande.
Public - 4 months ago
reviewed 4 months ago
Kanonbra, både för barn och leksugna vuxna. Fast dyrt är det ju såklart. Minst 1200:- för två vuxna och två barn.
Appeal: ExcellentFacilities: ExcellentService: Excellent
Public - 7 months ago
reviewed 7 months ago
God glass. Skarvglass kan köpas billigt.
Public - 8 months ago
reviewed 8 months ago
Appeal: Very goodFacilities: GoodService: Excellent
Public - 10 months ago
reviewed 10 months ago
8 reviews
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Trevligt litet fik precis vid busstorget. Bra mackor och sallader, hyfsat kaffe.
Food: Very goodDecor: GoodService: Very good
Public - 7 months ago
reviewed 7 months ago
God glass, mysig uteservering, trevlig personal och trevlig omgivning. Toalett är en bajamaja och inte så fräsch. Lite trångt att handla. De bygger en inneservering som nog löser en del av det negativa.
Public - 8 months ago
reviewed 8 months ago
Vansinnigt god vegetarisk lasagne. Bra mat över lag.
Public - 10 months ago
reviewed 10 months ago